International Journal of Nanomedicine,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 11463 - 11477
Published: Nov. 1, 2024
Deep,
second-
and
third-degree
burn
injuries
may
lead
to
irreversible
damage
the
traumatized
tissue
coagulation
or
thrombosis
of
microvessels,
further
compromising
wound
healing.
Engineered,
morphologically
gradient
drug-eluting
nanofiber
dressings
promote
healing
by
mimicking
structure
providing
sustained
drug
delivery,
which
is
particularly
beneficial
for
management.
Nano Biomedicine and Engineering,
Journal Year:
2024,
Volume and Issue:
16(2), P. 248 - 257
Published: Jan. 24, 2024
In
this
study,
we
harnessed
the
properties
of
desert
plants
to
synthesize
silver
nanoparticles
explore
potential
antimicrobial
solutions.
Chrozophora
plicata
and
Heliotropium
curassavicum
extracts
were
used
as
green
reducing
agents
transform
ions
into
nanoparticles.
Our
findings
revealed
novel
C.
plicata,
which
have
not
been
reported
before.
Surface
plasmon
resonance
peak
at
453.6
431
nm
for
H.
curassavicum,
respectively,
via
ultraviolet
(UV)
spectral
analysis
evidenced
successful
fabrication
with
particle
sizes
ranging
from
4.3–8
3.1–6.97
was
validated
by
field
emission
scanning
electron
microscopy
(FE-SEM).
X-ray
diffraction
that
crystal
structure
these
had
a
face-centered
cubic
geometry.
Fourier
infrared
spectrometry
plant
extract
showed
strong
signals
corresponding
carbohydrates,
proteins,
phenolics.
Antibacterial
assays
displayed
zones
inhibition
5
4
mm
against
Staphylococcus
aureusEscherichia
coli,
respectively.
Meanwhile,
exhibited
both
pathogens
10
7
mm,
The
test
samples
substantial
inhibitors
S.
E.
coli
biofilm
formation
since
IC50
values
in
range
8.88–10.57
mg/mL,
is
potent
reference
ciprofloxacin.
Consequently,
derived
can
be
drug
candidates
treating
respiratory
digestive
tract
infections
alone
or
combination
existing
antibiotics.
Coatings,
Journal Year:
2024,
Volume and Issue:
14(6), P. 666 - 666
Published: May 24, 2024
This
article
presents
the
biochemical
properties
of
poly(lactide)-zinc
(PLA-Zn)
composites
obtained
by
DC
magnetron
sputtering
zinc
onto
melt-blown
nonwoven
fabrics.
The
were
determined
evaluation
activated
partial
thromboplastin
time
(aPTT)
and
prothrombin
(PT).
antimicrobial
activity
PLA-Zn
samples
was
additionally
tested
against
representative
Gram-positive
Gram-negative
bacteria
strains.
A
structural
study
has
been
carried
out
using
specific
surface
area
total
pore
volume
(BET)
analysis,
as
well
atomic
absorption
spectrometry
with
flame
excitation
(FAAS).
exhibited
an
antibacterial
effect
analyzed
strains
produced
inhibition
zones
E.
coli
S.
aureus.
Biochemical
investigations
revealed
that
untreated
PLA
fibers
caused
acceleration
clotting
human
blood
plasma
in
intrinsic
pathway.
However,
demonstrated
significantly
different
this
regard,
aPTT
prolonged
while
PT
not
altered.
International Journal of Nanomedicine,
Journal Year:
2024,
Volume and Issue:
Volume 19, P. 11463 - 11477
Published: Nov. 1, 2024
Deep,
second-
and
third-degree
burn
injuries
may
lead
to
irreversible
damage
the
traumatized
tissue
coagulation
or
thrombosis
of
microvessels,
further
compromising
wound
healing.
Engineered,
morphologically
gradient
drug-eluting
nanofiber
dressings
promote
healing
by
mimicking
structure
providing
sustained
drug
delivery,
which
is
particularly
beneficial
for
management.
