Building HPV vaccine confidence through codesigned interventions with and for healthcare workers in Nigeria: protocol for a pilot cluster randomised controlled trial
BMJ Open,
Journal Year:
2025,
Volume and Issue:
15(4), P. e098308 - e098308
Published: April 1, 2025
Introduction
The
human
papillomavirus
(HPV)
vaccine
can
effectively
prevent
cervical
cancer,
yet
HPV
uptake
is
particularly
low
in
some
low-income
settings,
due
to
supply
and
confidence
barriers.
has
also
been
found
be
lacking
among
healthcare
workers
countries,
including
Nigeria.
Nigeria
a
long
history
of
parts
the
country.
rumours
concerns
have
observed
throughout
country,
workers.
Interventions
that
specifically
address
workers’
are
limited,
since
often
assumed
this
group.
aim
our
pilot
cluster
randomised
control
trial
(cRCT)
evaluate
feasibility
conducting
evaluates
codesigned
interventions
improve
acceptability
delivering
intervention.
Methods
analysis
This
3-arm
cRCT,
using
mixed-methods
approach
assess
design,
alongside
intervention
delivery
two
states
(Jigawa
Oyo).
We
will
implement
interventions:
one
with
focus
on
digital
delivery,
an
champion
present
at
health
facility.
Both
compared
arm,
providing
standard
information
only.
Overall,
12
clusters
(six
Jigawa
six
Oyo),
defined
as
government
primary
facilities,
1:1:1
ratio,
stratified
by
state.
All
within
these
facilities
eligible
take
part
evaluation.
outcome
interest
uptake,
measure
subsequent
given
around
contamination
clusters.
assessed
through
endline
worker
survey.
Intervention
quantitative
monitoring
qualitative
interviews
Ethics
dissemination
received
approval
from
State
Committee
(ref:
JGHREC/2023/151),
Ministry
Health
MOH/PH/PHRAT/MN/23/003),
Oyo
Research
Review
AD/13/479/362A),
University
Ibandan
College
Hospital
(UI/UCH
Committee)
UI/EC/23/308)
Swedish
National
Board
(2023-04772-01-471058).
Data
presented
manuscript
form
submitted
relevant
conferences
for
dissemination.
Registration
details
registered
ISRCTN—the
UK’s
Clinical
Study
Registry,
registration
number
ISRCTN37847119
.
Language: Английский
Serosusceptibility and hesitancy for booster HBV vaccination among health care workers in Italy: A cross-sectional study
Alessandro Godono,
No information about this author
Marco Clari,
No information about this author
Riccardo Corgiat Loia
No information about this author
et al.
Journal of Infection and Public Health,
Journal Year:
2024,
Volume and Issue:
17(6), P. 1095 - 1099
Published: April 17, 2024
Health
care
workers
(HCWs)
are
at
increased
risk
of
exposure
to
hepatitis
B
virus
(HBV).
The
most
effective
prevention
measure
is
vaccination,
with
a
serum
surface
antibody
(HBsAb)
titre
>10
mIU/ml
considered
protective.
To
date,
the
sociodemographic
and
occupational
characteristics
related
HBV
serosusceptibility
factors
associated
booster
hesitancy
remain
unclear.
Therefore,
this
study
aimed
identify
maintaining
protective
HBsAb
in
large
sample
HCWs
evaluate
potentially
towards
vaccine
boosters.
A
cross-sectional
was
conducted
among
who
underwent
health
surveillance
visit
between
2017
2022.
If
<10
MIU/ml,
dose
offered.
Based
on
their
willingness
be
vaccinated,
employees
were
classified
into
three
groups:
acceptance,
hesitation,
refusal.
Uni-
multivariable
analyses
performed
assess
association
demographic
attitudes
vaccination.
total
1,632
(27%)
shown
nonimmune.
lower
median
age
being
physician
significantly
titre.
706
nonimmune
(43.3%)
accepted
865
(53%)
hesitated,
61
(3.7%)
refused.
those
refused
vaccination
higher
than
that
hesitated
vaccinated.
Acceptance
nurses,
while
nurse
aides
more;
nonmedical
graduate
staff
both
hesitation
refusal
expected.
In
analysis,
age,
female
sex,
employment
as
an
allied
professional
hesitation/refusal,
born
abroad
turned
out
Our
showed
approximately
quarter
not
immune
infection,
these,
more
half
hesitant
or
dose.
hesitation/refusal
women
staff.
these
findings,
further
studies
needed
prospectively
seroprevalence,
adherence,
hesitancy,
effectiveness
strategies
high-risk
population
susceptible
infection.
Language: Английский
Influenza Vaccination of Romanian Medical Students during COVID-19 Times: From Knowledge to Behavior
Bianca Georgiana Enciu,
No information about this author
Andreea Marilena Păuna,
No information about this author
Carmen Daniela Chivu
No information about this author
et al.
Vaccines,
Journal Year:
2024,
Volume and Issue:
12(6), P. 594 - 594
Published: May 30, 2024
In
Romania,
influenza
vaccination
uptake
among
healthcare
workers
decreased
over
time
despite
access
to
the
vaccine
being
constantly
improved.
The
aim
of
this
paper
is
provide
a
comparative
analysis
knowledge
and
attitudes
Dental
Medicine
students
towards
recommended
vaccinations
for
workers,
focusing
on
vaccination.
A
cross-sectional
study
was
conducted
during
entire
2021–2022
academic
year.
Data
were
collected
using
2
electronic
questionnaires
which
applied
from
Faculty
(n
=
883)
and,
respectively,
Carol
Davila
University
Pharmacy,
Bucharest,
Romania.
offered
1187
completed
by
911
(response
rate
77%).
Out
these,
85%
778)
identified
as
recommended;
35%
321)
reported
getting
an
annual
vaccination;
37%
(333)
in
previous
season.
Overall,
45%
222)
respondents
who
October
2021
February
2022
that
they
intend
get
vaccinated
against
season
approximately
8%
39)
had
already
been
vaccinated.
multivariable
showed
habit
annually
well
all
associated
with
higher
probability
intending
current
emphasizes
need
raise
awareness
medical
regarding
involve
education
institutions,
public
health
authorities,
facilities
promoting
since
included
suboptimal.
Language: Английский
Active offer of Tdap vaccination in a cohort of healthcare workers of Maternal and Neonatal Department: Data from a large hospital in Southern Italy
Antonio Di Lorenzo,
No information about this author
Luca Capodiferro,
No information about this author
Michele Illuzzi
No information about this author
et al.
Vaccine X,
Journal Year:
2024,
Volume and Issue:
19, P. 100530 - 100530
Published: July 18, 2024
Pertussis
is
a
vaccine-preventable
respiratory
disease.
vaccination
currently
mandatory
for
all
children
in
Italy,
and
administered
three
doses
at
the
beginning
of
third,
fifth,
twelfth
month
life,
respectively.
Booster
are
also
recommended
five-six
years,
eleven-twelve
then
once
every
ten
years.
Healthcare
workers
(HCWs)
high-risk
population
pertussis.
Strategies
to
increase
HCWs'
compliance
this
have
not
been
investigated
depth.
Our
study
investigates
determinants
acceptance
"soft
nudge"
campaign
large
hospital
Apulia
(Southern
Italy).
HCWs
from
Gynaecology
Neonatology
Units
Bari's
Policlinico
General
Hospital
were
screened
June
2023
pertussis
vaccination.
Non-vaccinated
subjects
offered
appointment.
Vaccination
studied,
logistic
regression
model
was
built
identify
that
significantly
influence
acceptance.
At
time
screening,
only
31.34%
target
(68/217)
had
already
vaccinated.
After
active
call
intervention,
vaccine
coverage
rose
70.00%
(152/217).
Significantly
higher
found
Unit
(30/43,
69.77%)
than
unit
(54/106,
50.94%)
(Chi2:
4.41;
p-value:
0.036).
A
confirmed
staffed
2.08;
95%CI:
1.04
-
4.73;
0.038).
intervention
increased
cohort.
The
solicitation
effective,
as
communication
with
trained
specialist
might
improved
subjects'
perception
individual
risk
contagion
transmission
others.
synergistic
approach,
mixing
mandate,
greater
effectiveness.
Language: Английский