Replication Restriction of Influenza A(H5N1) Clade 2.3.4.4b Viruses by Human Immune Factor, 2023–2024 DOI Creative Commons
Jakob Ankerhold, Susanne Kessler, Martin Beer

et al.

Emerging infectious diseases, Journal Year: 2024, Volume and Issue: 31(1)

Published: Dec. 11, 2024

We show that human myxovirus resistance protein 1 (MxA) suppresses replication of highly pathogenic avian influenza A(H5N1) viruses isolated from mammals in vitro and MxA-transgenic mice. However, H5N1 can evade MxA restriction through replacement individual viral polymerase complex components a human-adapted MxA-resistant strain vitro.

Language: Английский

Endangered Galápagos sea lions and fur seals under the siege of lethal avian flu: a cautionary note on emerging infectious viruses in endemic pinnipeds of the Galápagos Islands DOI Creative Commons
Juan José Alava, Ana Tirapé, Judith Denkinger

et al.

Frontiers in Veterinary Science, Journal Year: 2024, Volume and Issue: 11

Published: Sept. 20, 2024

Language: Английский

Citations

0
Genetic evolution, phylodynamic and phylogeographic of H5Ny AIVs in mammals DOI Creative Commons
Hailiang Sun,

Zifeng Pang,

Cuishan Mai

et al.

Animals and zoonoses., Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Language: Английский

Citations

0
Replication Restriction of Influenza A(H5N1) Clade 2.3.4.4b Viruses by Human Immune Factor, 2023–2024 DOI Creative Commons
Jakob Ankerhold, Susanne Kessler, Martin Beer

et al.

Emerging infectious diseases, Journal Year: 2024, Volume and Issue: 31(1)

Published: Dec. 11, 2024

We show that human myxovirus resistance protein 1 (MxA) suppresses replication of highly pathogenic avian influenza A(H5N1) viruses isolated from mammals in vitro and MxA-transgenic mice. However, H5N1 can evade MxA restriction through replacement individual viral polymerase complex components a human-adapted MxA-resistant strain vitro.

Language: Английский

Citations

0