Nouvelles sources protéiques et nouveaux allergènes : sensibilisation de novo et réactivité croisée

Revue française d'allergologie, Journal Year: 2025, Volume and Issue: 65(3), P. 104203 - 104203

Published: Feb. 15, 2025

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Allergenicity in cultured meat: assessment and strategic management

Critical Reviews in Food Science and Nutrition, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 13

Published: April 29, 2025

As global population and demand for meat products rise, traditional livestock production faces major challenges in economic efficiency environmental sustainability. Cultured meat, produced through vitro cultivation of animal cells, has emerged as a promising alternative, offering notable public health benefits. However, safety concerns persist owing to differences technology materials compared with conventional food production. Additionally, comprehensive evaluation newly expressed proteins allergenic potential is essential. This review examines cultured processes explores allergenicity assessment methods used genetically modified organisms, aiming propose an approach tailored meat. Prioritizing crucial ensuring genomic proteomic equivalence conventionally foods. It also necessary assess the presence novel sensitization integrated analysis. The framework proposed this study will support development regulatory systems preventing consumer incidents associated these products.

Language: Английский

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Analysis of trends and allergenicity risk assessments in novel food approvals within the European Union between 2018 and 2023

Food and Chemical Toxicology, Journal Year: 2025, Volume and Issue: unknown, P. 115249 - 115249

Published: Jan. 1, 2025

Novel food (NF) approvals in the European Union between 2018 and 2023 (n = 117) were retrieved analysed. They consist of new NF (52.1%), modification (38.5%), traditional (9.4%). The average time taken for applications to be approved was 38 months 2023, with clock-stops occurring all since 2020. For NFs, only 21.3% 9.8% performed tests by bioinformatics homology immunological analyses respectively, suggesting that allergenicity assessments remain a challenge. Allergenicity risks regarded as possible 47.5% approvals, while 52.5% expected low, very or unlikely. However, it not always clear what decision based on. While protein intake levels rarely mentioned conclusions NFs typically had exceeding 1 mg/day. Establishing dose represents Threshold Allergological Concern below which is unlikely cause sensitisation consumers, could make de novo assessment more feasible. This approach might exempt certain proteins from testing, instead focusing on allergenic relevance.

Language: Английский

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Chemical and Microbiological Characterization of Freeze-Dried Superworm (Zophobas morio F.) Larvae Pretreated by Blanching and Ultrasound Treatment

Molecules, Journal Year: 2024, Volume and Issue: 29(22), P. 5447 - 5447

Published: Nov. 19, 2024

Edible insects may solve the current problem of greater demand for food world's growing human population. This work aimed to examine impact blanching (BL) and ultrasound (US) at 20 50 °C as a pretreatment method on chemical composition, mineral FTIR spectra, presence allergens microorganisms, properties isolated oil freeze-dried superworm larvae. The US treatment resulted in significantly lower protein content (31.65-33.34 g/100 g d.m.) compared untreated (36.38 BL (37.72 samples. study demonstrated that US-treated exhibited crustacean mollusk than insects, lowest tested was found US_50°C Furthermore, from SFA highest PUFA best prospective nutritional expressed through theoretical health indices. Enterobacteriaceae anaerobic spore-forming bacteria not detected proving suitable microbiological quality. It appears using is promising alternative traditional before drying.

Language: Английский

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New dietary trends and alternative proteins: the emergence of novel food allergens

Current Opinion in Clinical Nutrition & Metabolic Care, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 17, 2024

Purpose of the review New dietary trends driven by environmental and health considerations will undoubtedly lead to emergence novel food allergens. Assessment allergenic risk new or modified protein-containing sources ingredients, as well surveillance emerging allergies, is then required. Recent findings Developments in silico vitro models apprehending protein capacity cross-react with other homologous proteins induce a de novo allergic sensitization are ongoing better integrate multiple parameters such 3D structural information major histocompatibility complex class II (MHC-II) presentation propensity. However, effects matrices processing still need be addressed these models. Consequently, clinical postmarket remain critical importance alert on emergent which modulated regional practices. Summary Monitoring allergens requires close collaborations between allergologists, consumers, patient associations safety authorities. We also get consensus an acceptable level that offers possibility develop market innovative sustainable products.

Language: Английский

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A review on the characterization of edible scaffolds for cultured meat: Physical, chemical, biocompatibility, and food safety evaluation methods

Food Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 142493 - 142493

Published: Dec. 1, 2024

Language: Английский

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