Natural Product Research, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 9
Published: Dec. 13, 2024
Cannabis oil, derived from
Language: Английский
International Journal of Science and Research Archive, Journal Year: 2024, Volume and Issue: 11(1), P. 2502 - 2539
Published: Feb. 28, 2024
This review paper has highlighted a list of plants containing active phytochemicals with anticancer potential, as well data supporting their use in cancer therapy, animal models, and pharmacological properties. Cancer is among the leading causes morbidity mortality worldwide. disease characterized by abnormal cell division proliferation that result from disruption molecular signals control these processes. abnormal, uncontrolled cells body. The when malignant, invade various parts body through bloodstream. spread its or tissue origin to another healthy part tissues organs called metastasis. Some regular characteristics cancers are apoptosis, angiogenesis, multiple replication, growth signal production, insensitivity anti-growth These features make have continuous growth, long time survival potential normal cells. Moreover, if activities not blocked, will continue increase, overwhelm finally kill patient cancer. Oncology study An oncologist doctor who treats provides medical care for person diagnosed may also be specialist. Today, despite considerable efforts, still remains an aggressive killer success rate therapies diminished toxicities, drug resistance, recurrence treatment failure. A significant challenge associated much art it science. Therefore, there constant demand develop new, effective, affordable drugs. Several factors, such environmental habitual activities, genetic etc., responsible Many patients seek alternative and/or complementary treatments because high death linked adverse side effects chemotherapy, radiation immunotherapy, surgery, stem therapy. Medicinal could possess effective compounds used adjuvants existing chemotherapy improve efficacy reduce drug-induced toxicity; chemotherapy-induced nausea vomiting patients’ quality life. Cell caused whole plant extracts via apoptosis. However, majority been researched prevention rather than treatment, resulting low uptake practice. Prevention certainly attractive management strategy. Thus might possible process carcinogenesis along lifestyle.
Language: Английский
Citations
8
World Journal of Biology Pharmacy and Health Sciences, Journal Year: 2024, Volume and Issue: 17(2), P. 253 - 296
Published: Feb. 20, 2024
This litrature review paper highlights the role of phytocannabinoids in controlling cervical cancer. Cervical cancer is one leading causes death among females worldwide. (CC) a malignant form tumor which originates cervix. cancer, develops woman’s cervix, second-most common women India The causative agent persistent infection with high-risk subtypes Human Papillomavirus (HPV) and E5, E6 E7 viral onco-proteins cooperate host factors to induce maintain phenotype. papillomavirus responsible for subclinical/clinical lesions HPV types 16 18 are most identified invasive Currently, recommended therapeutic regimens include chemotherapy, radiation therapy either alone or combination surgical interventions. However, they present several limitations including side effects ineffectiveness. Medicinal plants Cannabis sativa have been used decades health benefits treat different diseases has thousands years recreational, medicinal, religious purposes. Phytocannabinoids cannabinoids that occur naturally cannabis plant. two well known their properties are, Δ9-tetrahydrocannabinol (THC) Cannabidiol (CBD). hold big promise therapy. there need understand more about Endocannabinoid system (ECS) normal human physiology transformations. Molecular mechanisms regulation anticancer also be clarified. treatment durations existing trials concern. Future epidemiological clinical studies required further assess herbal medicines prevention In addition, preclinical trial evaluations not specifically conducted, so investigations related this warranted. Therefore, immunization programme best ideal solution eradication
Language: Английский
Citations
4
Cuadernos de Educación y Desarrollo, Journal Year: 2025, Volume and Issue: 17(2), P. e7635 - e7635
Published: Feb. 25, 2025
A cicatrização de feridas e o manejo da dor pós-cirúrgica são desafios significativos na prática clínica. O canabidiol (CBD), um fitocanabinoide não psicoativo planta Cannabis sativa, tem emergido como uma opção terapêutica promissora devido às suas propriedades anti-inflamatórias, analgésicas regenerativas. Este artigo revisa as evidências científicas sobre uso do CBD nas diferentes fases feridas—incluindo inflamação, proliferação remodelação—e seu potencial para aliviar a pós-cirúrgica. atua principalmente por meio modulação sistema endocanabinoide (ECS), regulando inflamação promovendo regeneração tecidual. Sua aplicação tópica demonstrado reduzir formação cicatrizes acelerar cicatrização, além possuir antimicrobianas que ajudam prevenir infecções. No dor, pode necessidade opioides, minimizando os riscos dependência outros efeitos colaterais. Apesar terapêutico, transição clínica exige ensaios clínicos rigorosos confirmar eficácia segurança CBD, padronização das formulações vias administração. Conclui-se grande revolucionar tratamentos melhorando resultados qualidade vida dos pacientes.
Citations
0
Published: Jan. 1, 2025
Language: Английский
Citations
0
Advances in computational intelligence and robotics book series, Journal Year: 2025, Volume and Issue: unknown, P. 143 - 172
Published: April 11, 2025
As AI becomes more integrated into marketing practices, understanding the balance between leveraging for personalized and protecting consumer privacy is crucial sustainable business practices. The chapter will explore intersection of in with ethical challenges concerns. It provide a comprehensive analysis how technologies are reshaping strategies, dilemmas that arise, importance safeguarding privacy.
Language: Английский
Citations
0
Open Access Research Journal of Biology and Pharmacy, Journal Year: 2024, Volume and Issue: 10(2), P. 028 - 071
Published: March 23, 2024
This review paper highlights and updates the role of plant based inhibitors in controlling triple-negative breast cancer (TNBC) via blocking TNBC signalling pathways. Breast is most common women. There are several identified types, among which fatal for patients. Conventionally, defined by lack estrogen receptor (ER), progesterone (PR), human epidermal 2 (HER2) cells. It well-known its metastatic, aggressive characteristics poor outcome clinic. Till today, treatment patients still a challenging task due to absence appropriate targets drugs. Despite successes emerging targeted therapies, relapse, recurrence, therapy failure rates significantly outpace other subtypes cancer. Mounting evidence suggests an accumulation resistant, Cancer Stem Cell (CSC) populations within TNBCs contributes clinical outcomes. These Cells enriched compared non-TNBC cancers. Approximately 60% drugs currently used have been isolated from natural products. Natural products treasure house development novel anticancer Many plant-derived compounds anti-cancer properties, including berberine quercetin, formononetin, calycosin, polyphenols, bioflavonoids, carotene, vitamins, andminerals. compounds, vinka alkaloids, vinblastine vincristine, luteolin, α-mangostin, piperine, silibinin, apigenin, fisetin, resveratrol, genistein, 10-gingerol, chalcones, curcumin, epigallocatechin gallate, cyanidin-3-O-glucoside, glycyrrhizin, shown especially TNBCs. Therefore, more trial data warranted further evaluation extracts
Language: Английский
Citations
3
World Journal of Biology Pharmacy and Health Sciences, Journal Year: 2024, Volume and Issue: 17(3), P. 140 - 179
Published: March 16, 2024
This review paper highlights the role of phytocannabinoids in controlling triple-negative breast cancer (TNBC). Triple-negative (TNBC) is a specific subtype that does not express estrogen receptor (ER), progesterone (PR), or human epidermal growth factor 2 (HER-2), which has clinical features include high invasiveness, metastatic potential, proneness to relapse, and poor prognosis. TNBC one most aggressive subtypes often associated with patient outcomes because development metastases secondary organisms like brain, bone, lungs. kind have any receptors are commonly found cancer. The highest number cases been recorded India. Currently, highly prevalent among Indian women develops approximately 20% 43% all patients an malignancy requires effective targeted drug therapy. Patients develop metastasis recurrence over time reduced survival compared other Pre-clinical studies demonstrated exert important antitumor properties main subtypes, particularly TNBC, where different synthetic cannabinoids shown interesting therapeutic actions. Neither CBD nor THC universally efficacious reducing cell viability. Focusing on vitro studies, effect viability ranges from no effect, modest reduction, significant cytotoxicity depending concentrations, lines, conditions, performed assays, exposure. However, it should also be noted research into efficacy, dosage safety tumor therapy still long way go, especially regard trials conducted, through alone benefits advantages for but possible risks can defined.
Language: Английский
Citations
1
World Journal of Advanced Research and Reviews, Journal Year: 2024, Volume and Issue: 23(2), P. 2634 - 2686
Published: Aug. 30, 2024
This review paper of literature highlights the importance greenhouse urban farming technology, hydroponics, aeroponics, aquaponics, vertical and applications Internet Things (IOT) technologies. The is a well known modern agriculture technology for optimal plant growth. Hydroponics, soilless cultivation technique using nutrient solutions under controlled conditions, used growing vegetables, high-value crops, flowers. Vertical popular trend in hydroponics that involves stacking multiple layers plants arrangement. method saves space, reduces water usage, increases yields per square foot area. In comparison to conventional cultivation, requires less fertilizer, pesticides, due precise control over their distribution. term “Internet (IOT)” system interconnected computing devices, sensors, objects, microcontrollers, cloud servers can transmit data across network other devices remotely without human intervention. A better management solution hydroponic systems optimum pH, electrical conductivity (EC), or ions concentration. three main gases (GHGs) emissions hi-tech are nitrous oxide, methane carbon dioxide (CO2). To measure levels CO2 more intermediate advanced grower use monitoring controllers system. Hydroponic infancy India. Although units production crops like strawberry, lettuce leafy foliage flowers functioning major metros However, organized farms food not available Therefore, only few successful have been built India mainly initial high price tag on construction cost maintaining them afterwards. Another disadvantage footprint very high, discourages its applications.
Language: Английский
Citations
1
Recent Advances in Drug Delivery and Formulation, Journal Year: 2024, Volume and Issue: 18(4), P. 247 - 261
Published: July 23, 2024
: Medical cannabis has potential therapeutic benefits in managing pain, anxiety, depression, and neurological movement disorders. Phytocannabinoids derived from the plant are responsible for their pharmacological properties. However, complexity of components, especially cannabinoids, poses a challenge to effective medicinal administration. Even with increasing acceptance cannabis-based medicines, achieving consistent bioavailability targeted distribution remains difficult. Conventional administration methods plagued by solubility absorption problems requiring innovative solutions. After conducting thorough review research papers patents, it become evident that nanotechnology holds great promise as solution. The comprehensive 36 yielded valuable insights, 7 reporting enhanced bioavailability, while others have focused on improvements release, solubility, stability. Additionally, 19 patents been analyzed, which specifically claim remaining describe various formulation methods. These outline techniques encapsulating using nanocarriers, effectively addressing controlled release. Studies delivery nanocarriers focus improving prolonging targeting specific areas. This synthesis highlights enhance therapies pave way interventions precision medicine.
Language: Английский
Citations
0
Psychology Crime and Law, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 9
Published: Aug. 1, 2024
Many studies have compared individuals who use cannabis for recreational versus medical purposes, but little is known about the moral norms and risk perceptions toward while driving. This study aims to examine young Israeli adults' behaviors, perceived norms, regarding driving under influence of cannabis. Methods: The was conducted using quantitative questionnaires. Participants were 504 adults, aged 18–30 (M = 25.26; SD 5.40), whom 314 (62.3%) women. Results: Driving as more less risky than Significant positive correlations observed between both types negative found frequency associated with Conclusion: Policymakers should promote prevention, harm reduction, enforcement interventions address issue
Language: Английский
Citations
0