Public Health Threats Posed by Biofilms and Innovative Strategies for their Control DOI Open Access

Syed Hamza Abbas,

Shahzar Khan,

M.J. Shah

et al.

Discoveries, Journal Year: 2024, Volume and Issue: 12(4), P. e197 - e197

Published: Dec. 31, 2024

Biofilms are communities of microorganisms that adhere to surfaces within a self-produced protective matrix. The structural complexity biofilms and their inherent resistance conventional antimicrobial treatments make them significant public health challenge. These microbial communities, embedded extracellular matrix, associated with numerous persistent infections, especially those occurring in healthcare settings where they colonize medical devices chronic wounds. effects go beyond environments persist water treatment facilities, food processing plants, nature, which aid pollution transmission disease. This review article discusses multifaceted complications related the search for existing control strategies, process biofilm formation, mechanisms persistence, limitations traditional approaches. Additionally, this explores new innovative solutions, such as bacteriophage therapy, matrix-degrading enzymes, quorum sensing inhibitors. potential combination agents biofilm-disrupting compounds improvement efficacy is also paid special attention. seeks contribute these ongoing efforts by presenting an overview biology assessing variety possible strategies. Subsequently, insights derived from study may be used inform future research directions development more effective interventions biofilm-associated infections contamination various settings.

Language: Английский

Optical sensor system for analysis of planktonic and biofilm bacteria DOI
А. В. Шелудько, Stella S. Yevstigneyeva, Е. М. Телешева

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113157 - 113157

Published: Feb. 1, 2025

Language: Английский

Citations

0
Isolation of Pseudonocardia strains associated with the shallow water hydrothermal vent crab Xenograpsus testudinatus from a metal-rich environment: biochemical characterization and enzymatic characterization, molecular identification, antibacterial, antibiofilm and antioxidant activity DOI
Johnthini Munir Ahamed, Hans‐Uwe Dahms, Nikolaos V. Schizas

et al.

Microbial Pathogenesis, Journal Year: 2025, Volume and Issue: unknown, P. 107457 - 107457

Published: March 1, 2025

Language: Английский

Citations

0
Bacterial Biofilms—A Threat to Biliary Stents, Understanding Their Formation, Clinical Consequences and Management DOI Creative Commons
Jolanta Gruszecka, Rafał Filip

Medicina, Journal Year: 2025, Volume and Issue: 61(3), P. 512 - 512

Published: March 16, 2025

A biofilm is a community of microbial cells which are enclosed in an external matrix and separated by network water channels attached to natural or artificial surfaces. Biofilms formed inside biliary stents consist mixed spectrum bacterial communities, most usually originate from the intestines. The patency important problem. Stent occlusion can threaten health even life patients. main cause this phenomenon bile sludge, excellent environment for multiplication existence microorganisms. Due great clinical importance maintaining stents, several methods have been developed prevent accumulation sludge subsequent formation biofilm; these include, among others, use anti-adhesive materials, coating inner surface with metal cations (silver, copper) other antimicrobial substances, implementation biodegradable drug-eluting development new stent design anti-reflux effect. This article presents latest information on biofilms as well historical future prevention.

Language: Английский

Citations

0
Public Health Threats Posed by Biofilms and Innovative Strategies for their Control DOI Open Access

Syed Hamza Abbas,

Shahzar Khan,

M.J. Shah

et al.

Discoveries, Journal Year: 2024, Volume and Issue: 12(4), P. e197 - e197

Published: Dec. 31, 2024

Biofilms are communities of microorganisms that adhere to surfaces within a self-produced protective matrix. The structural complexity biofilms and their inherent resistance conventional antimicrobial treatments make them significant public health challenge. These microbial communities, embedded extracellular matrix, associated with numerous persistent infections, especially those occurring in healthcare settings where they colonize medical devices chronic wounds. effects go beyond environments persist water treatment facilities, food processing plants, nature, which aid pollution transmission disease. This review article discusses multifaceted complications related the search for existing control strategies, process biofilm formation, mechanisms persistence, limitations traditional approaches. Additionally, this explores new innovative solutions, such as bacteriophage therapy, matrix-degrading enzymes, quorum sensing inhibitors. potential combination agents biofilm-disrupting compounds improvement efficacy is also paid special attention. seeks contribute these ongoing efforts by presenting an overview biology assessing variety possible strategies. Subsequently, insights derived from study may be used inform future research directions development more effective interventions biofilm-associated infections contamination various settings.

Language: Английский

Citations

0