Manas Journal of Agriculture Veterinary and Life Sciences,
Journal Year:
2024,
Volume and Issue:
unknown, P. 201 - 209
Published: Oct. 22, 2024
Hepatocellular
carcinoma
(HCC)
is
defined
as
the
sixth
most
common
cancer
type
and
third
in
terms
of
cancer-related
deaths.
Tarantula
cubensis
alcohol
extract
(TCAE,
Theranekron)
a
homeopathic
medicine
frequently
used
veterinary
treatment
papilloma,
mammary
adenocarcinoma
necrotic
disorders.
The
present
study
aimed
to
reveal
effectiveness
TCAE
Sorafenib
(S)
HCC
induced
by
Diethylnitrosamine
(DEN)
N-nitrosomorpholine
(NMOR)-induced
rats.
Rats
were
randomly
divided
into
7
groups:
Control
(C),
+
(CT),
S
(CS),
Cancer
(CC),
CC+TCAE
(CCT),
CC+S
(CCS),
CC+TCAE+S
(CCTS).
In
CC
group,
values
for
glucose,
triglyceride
(TG)
total
antioxidant
capacity
(TAC)
found
be
significantly
higher
than
all
other
groups
(p<0.001),
while
p21
levels
lower
(p<0.05).
It
determined
an
increase
serum
(p<0.05)
significant
decrease
glucose
TG
(p<0.001)
CCT,
CCS
CCTS
compared
group.
Histopathological
examination
revealed
that
group
showed
morphology,
caused
tumor
incidence
size.
As
result,
it
can
said
alone
and/or
combined
with
chemotherapy
drugs
antiproliferative
effects
on
cells
HCC.
combination
therapy
may
potentially
synergize
improve
magnitude
durability
antitumor
responses
patients
Expert Review of Molecular Diagnostics,
Journal Year:
2024,
Volume and Issue:
24(9), P. 803 - 827
Published: Aug. 28, 2024
Primary
liver
cancer
is
a
major
health
problem
being
the
sixth
most
frequent
in
world
and
third
cause
of
cancer-related
death
world.
The
common
histological
type
hepatocellular
carcinoma
(HCC,
75-80%).
Pharmaceutics,
Journal Year:
2024,
Volume and Issue:
16(11), P. 1432 - 1432
Published: Nov. 10, 2024
Itraconazole
(ITZ)
is
an
antiangiogenic
agent
recognized
as
a
potent
suppressor
of
endothelial
cell
growth
that
suppresses
angiogenesis.
Nevertheless,
its
exploitation
significantly
restricted
by
low
bioavailability
and
systematic
side
effects.
The
objective
this
study
was
to
utilize
glycerosomes
(GLY),
glycerol-developed
vesicles,
innovative
nanovesicles
for
successful
ITZ
pulmonary
drug
delivery.
Manas Journal of Agriculture Veterinary and Life Sciences,
Journal Year:
2024,
Volume and Issue:
unknown, P. 201 - 209
Published: Oct. 22, 2024
Hepatocellular
carcinoma
(HCC)
is
defined
as
the
sixth
most
common
cancer
type
and
third
in
terms
of
cancer-related
deaths.
Tarantula
cubensis
alcohol
extract
(TCAE,
Theranekron)
a
homeopathic
medicine
frequently
used
veterinary
treatment
papilloma,
mammary
adenocarcinoma
necrotic
disorders.
The
present
study
aimed
to
reveal
effectiveness
TCAE
Sorafenib
(S)
HCC
induced
by
Diethylnitrosamine
(DEN)
N-nitrosomorpholine
(NMOR)-induced
rats.
Rats
were
randomly
divided
into
7
groups:
Control
(C),
+
(CT),
S
(CS),
Cancer
(CC),
CC+TCAE
(CCT),
CC+S
(CCS),
CC+TCAE+S
(CCTS).
In
CC
group,
values
for
glucose,
triglyceride
(TG)
total
antioxidant
capacity
(TAC)
found
be
significantly
higher
than
all
other
groups
(p<0.001),
while
p21
levels
lower
(p<0.05).
It
determined
an
increase
serum
(p<0.05)
significant
decrease
glucose
TG
(p<0.001)
CCT,
CCS
CCTS
compared
group.
Histopathological
examination
revealed
that
group
showed
morphology,
caused
tumor
incidence
size.
As
result,
it
can
said
alone
and/or
combined
with
chemotherapy
drugs
antiproliferative
effects
on
cells
HCC.
combination
therapy
may
potentially
synergize
improve
magnitude
durability
antitumor
responses
patients
