The role of self-reported and physiological stress in nocebo hyperalgesia. DOI Creative Commons
Aleksandrina Skvortsova, Stefanie H. Meeuwis, Suzanne M.J.C. Derksen

et al.

Biological Psychology, Journal Year: 2024, Volume and Issue: 190, P. 108818 - 108818

Published: May 17, 2024

Negative expectations can increase pain sensitivity, leading to nocebo hyperalgesia. However, the physiological and psychological factors that predispose individuals this phenomenon are still not well understood. The present study examined whether stress induced by a social stressor affects hyperalgesia, effect is mediated self-reported responses. We recruited 52 healthy participants (15 men) who were randomly assigned either Trier Social Stress Test (TSST) or control condition (a friendly version of TSST). Nocebo hyperalgesia was using negative suggestions combined with validated conditioning paradigm. assessed (anxiety stress) (cortisol, alpha-amylase, heart rate, skin conductance) responses stress. Both groups exhibited significant group showed higher levels anxiety, stress, cortisol compared while no differences found in other markers. did differ magnitude but anxiety partially effects test on Our findings suggest an external does directly affect increased due enhances its magnitude. Thus, it may be worthwhile investigate reducing stress-related clinical settings would help alleviate effects.

Language: Английский

The role of self-reported and physiological stress in nocebo hyperalgesia. DOI Creative Commons
Aleksandrina Skvortsova, Stefanie H. Meeuwis, Suzanne M.J.C. Derksen

et al.

Biological Psychology, Journal Year: 2024, Volume and Issue: 190, P. 108818 - 108818

Published: May 17, 2024

Negative expectations can increase pain sensitivity, leading to nocebo hyperalgesia. However, the physiological and psychological factors that predispose individuals this phenomenon are still not well understood. The present study examined whether stress induced by a social stressor affects hyperalgesia, effect is mediated self-reported responses. We recruited 52 healthy participants (15 men) who were randomly assigned either Trier Social Stress Test (TSST) or control condition (a friendly version of TSST). Nocebo hyperalgesia was using negative suggestions combined with validated conditioning paradigm. assessed (anxiety stress) (cortisol, alpha-amylase, heart rate, skin conductance) responses stress. Both groups exhibited significant group showed higher levels anxiety, stress, cortisol compared while no differences found in other markers. did differ magnitude but anxiety partially effects test on Our findings suggest an external does directly affect increased due enhances its magnitude. Thus, it may be worthwhile investigate reducing stress-related clinical settings would help alleviate effects.

Language: Английский

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