Sedative effects of roasted green tea aroma on autonomic nervous activity, central nervous activity, and subjective mood state in healthy adults
Akio SUGIMOTO,
No information about this author
Y. Tatsumi,
No information about this author
Masaki Ichitani
No information about this author
et al.
Functional Foods in Health and Disease,
Journal Year:
2025,
Volume and Issue:
15(1), P. 68 - 87
Published: Jan. 15, 2025
Introduction:
To
clarify
the
physiological
and
psychological
effects
of
roasted
green
tea
aroma,
this
study
examined
extract
its
major
aromatic
components
on
autonomic
nervous
activity,
central
subjective
mood
state.
Methods:
Twenty
healthy
adults
who
were
not
averse
to
aroma
tea,
did
smoke,
display
any
flu
symptoms,
receiving
drug
treatment
participated
in
study.
The
samples
comprised
a
from
Shizuoka
first-growth
(Test
I)
three
pyrazines,
which
are
main
III).
pupil
miosis
rate,
peripheral
skin
temperature,
cerebral
blood
flow
measured
after
2
min
inhalation
as
evaluations.
Subjective
state
was
investigated
using
questionnaire
for
evaluation.
Results:
results
showed
that
significantly
increased
pupillary
rate
similar
observed
with
hot
water.
Furthermore,
reduced
amount
oxygenated
hemoglobin
prefrontal
cortex,
suggesting
it
also
has
sedative
effect
system.
In
evaluation
Visual
Analog
Scale,
scores
“tension”,
“anxiety”
while
increasing
those
“mood”
“comfort”
relative
addition,
specifically
different
demonstrated
even
at
room
temperature
when
tested
concentrations
derived
analysis.
Conclusion:
both
differ
water
suggest
these
pyrazines
play
role
producing
effects,
2,3,5-trimethylpyrazine
being
most
important
component.
findings
exerts
system
by
suppressing
sympathetic
nerve
activity
parasympathetic
activity.
Language: Английский
The benefits of terpenoids as functional foods for the managementof type 2 diabetes mellitus
Danik Martirosyan,
No information about this author
S. Christopher
No information about this author
Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426,
Journal Year:
2024,
Volume and Issue:
7(7), P. 345 - 347
Published: Aug. 1, 2024
Millions
of
people
worldwide
are
living
with
type
2
diabetes,
and
the
numbers
rising
at
an
unsustainable
rate.
Furthermore,
many
those
diabetes
suffer
from
micro
macrovascular
complications
that
limit
their
quality
life
longevity
as
well
impose
a
significant
financial
burden
on
individuals
health
systems
worldwide.
Many
reliant
oral
medications
or
combination
injectable
insulin
treatment
for
multiorgan
unregulated
prolonged
states
high
blood
sugar
levels.
these
obstacle
to
adherence
due
side
effects,
which
include
but
not
limited
gastrointestinal
discomfort,
headaches,
urinary
tract
infections,
hypoglycemia.
For
uninsured
underinsured
in
United
States
developing
countries,
cost
is
additional
determines
leads
undesirable
complications.
These
drawbacks
current
pharmacological
treatments
have
led
interest
research
into
various
bioactive
compounds
phytochemicals
such
alkaloids,
polyphenols,
flavonoids,
terpenoids
use
functional
foods
mitigate
advance
diabetes.
This
editorial
focuses
aims
review
certain
within
subclasses
being
researched
effectiveness
treating
and,
thereby,
potential
food
product.
Language: Английский
Effects and medical application of plant-origin polyphenols: A narrative review
G Janigashvili,
No information about this author
I Chkhikvishvili,
No information about this author
L Ratiani
No information about this author
et al.
Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426,
Journal Year:
2024,
Volume and Issue:
7(8), P. 375 - 385
Published: Aug. 31, 2024
The
impact
of
oxidative
stress
in
the
pathogenesis
various
diseases
is
well
known.
Oxidative
occurs
when
there
an
imbalance
between
production
reactive
oxygen
species
(ROS)
and
ability
a
biological
system
to
detoxify
these
intermediates
or
repair
resulting
damage.
Polyphenols,
diverse
group
compounds
with
antioxidant
properties,
help
reduce
damage
by
ROS.
They
are
abundant
fruits,
vegetables,
tea,
coffee,
wine,
other
plant-based
foods.
mechanisms
their
activity
related
regulate
cellular
signaling
pathways,
metal
chelation,
mitochondrial
protection,
while
modulating
enzyme
exhibiting
anti-inflammatory
effects.
Polyphenols
can
also
through
ROS
scavenging,
direct
neutralization,
enhancing
defenses
within
cells.
It
has
been
established
that
polyphenols
derived
from
plant
do
not
harm
metabolism
normal
cells,
but
involved
metabolic
pathways
diseased
which
high
redox
sensitivity.
Incorporating
polyphenol-rich
foods
into
diet
beneficial
for
maintaining
overall
health
reducing
risk
stress-related
diseases.
Researchers
exploring
therapeutic
potential
as
dietary
supplements
functional
medical
applications.
This
review
discusses
origin,
structure,
benefits,
application
medicine
food
industry.
Keywords:
biologically
active
compounds,
polyphenols,
stress,
activity,
food.
Language: Английский
Comparing the FDA's process for health claim submission and the FFC's guidelines for regulating functional foods
Sarah Stratton,
No information about this author
Danik Martirosyan
No information about this author
Functional Foods in Health and Disease,
Journal Year:
2023,
Volume and Issue:
13(9)
Published: Sept. 11, 2023
Health
claims
are
essential
for
providing
accurate
information
about
the
relationship
between
nutrients
and
health
outcomes
to
consumers.
They
facilitate
informed
decision-making
support
individuals
in
making
healthy
dietary
choices.
The
U.S.
Food
Drug
Administration
(FDA)
regulates
guide
consumers
maintaining
practices.
on
food
labels
help
understand
potential
benefits
associated
with
specific
products
make
choices
aligned
their
goals.
These
also
promote
transparency
trust
industry
by
evidence-based
information.
process
of
submitting
a
claim
FDA
involves
complying
regulatory
requirements
robust
scientific
evidence.
Scientific
evidence
plays
crucial
role
substantiating
should
be
based
well-designed
clinical
trials,
epidemiological
studies,
mechanistic
research.
Adhering
labeling
ensures
informative
presentation
labels.
Functional
Center
(FFC)
is
working
theoretical
aspects
creating
ideal
functional
(FF)
as
well
how
these
identified
special
FF
While
focuses
evaluating
claims,
FFC
emphasizes
safe
effective
use
foods.
Understanding
FDA's
evaluation
FFC's
guidelines
researchers,
manufacturers,
policymakers
navigate
landscape
consumer
Compliance
guidelines,
adherence
standards,
clear
communication
contribute
more
health-conscious
society.Keywords:
outcomes,
requirements,
foods,
Language: Английский
Bioactive Protein and Peptides; A Potential Pharma Ingredient for 21st Century Functional Foods
Nursing & Healthcare International Journal,
Journal Year:
2023,
Volume and Issue:
7(4)
Published: Jan. 1, 2023
Bioactive
peptides
have
upsurge
advancement
in
food
and
health
domains
recent
years.
This
was
driven
by
the
understanding
of
amino
acid
structure
functions
plant
animal
as
bioactive
peptide
sources.
The
functionality
bioactivities
are
their
function
-structure
relationships.
interplay
between
function-structure
protein
polypeptides
from
native
state
to
denature
has
opened
new
research
waveband
much
needed
innovative
ingredient
or
recipes
formulate
functional
foods
on
our
shelves,
however,
this
is
far
more
important
than
pharmaceutical
drugs
but
now
décor
pharma
foods.
Application
for
making
so
develop,
utilize,
manage
population,
family
individual
chronic
disease
conditions
were
emphasized.
Aligning
ingestion
peptides,
enveloped
with
circadian
rhythm
metabolic
curves
within
appropriate
time
scale
enhanced
nutrition
could
maximize
absorption,
utilization,
responses.
Hence,
use
potential
societal
interventions
overall
up.
Language: Английский
Addressing vitamin D deficiency through nutritional strategies
Tori Trachtenberg,
No information about this author
Danik Martirosyan
No information about this author
Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426,
Journal Year:
2024,
Volume and Issue:
7(6), P. 289 - 301
Published: June 21, 2024
This
review
explores
the
multifaceted
impacts
of
vitamin
D
deficiency
on
overall
health
and
investigates
diverse
strategies
for
addressing
this
issue.
Vitamin
presents
a
global
issue
with
notable
implications
cardiovascular,
immune,
brain
health.
Strategies
to
address
encompass
dietary
modifications,
food
fortification,
supplementation.
Serum
25(OH)D
concentration
serves
as
crucial
biomarker,
levels
below
20
ng/mL
being
indicative
deficiency.
Tailored
supplementation
regimens,
often
favoring
D3
its
enhanced
bioavailability,
necessitate
careful
consideration
avoid
toxicity
risks.
The
incorporation
D-fortified
foods
into
patterns
promising
systematic
approach
mitigating
promoting
Functional
Food
Center's
regulatory
process
offers
structured
framework
creating
products
fortified
D,
emphasizing
importance
compliance
clinical
validation.
While
existing
evidence
underscores
efficacy
products,
ongoing
epidemiological
post-market
research
is
imperative
fully
establish
their
status
functional
foods.
Keywords:
deficiency,
intake,
supplementation,
bioactive
compounds,
Language: Английский
Red Panax ginseng root promotes neuronal plasticity in vitro and improves cognitive function in aged animals
Camille Lelong,
No information about this author
Antoine Mandoux,
No information about this author
Nicolas Houyoux
No information about this author
et al.
Functional Foods in Health and Disease,
Journal Year:
2024,
Volume and Issue:
14(8), P. 574 - 588
Published: Aug. 8, 2024
Background:
Cognitive
function
declines
with
aging,
primarily
due
to
reduced
neuronal
plasticity,
decreased
release
of
trophic
factors,
and
stress.
Genetic
environmental
factors
have
been
shown
impact
cognitive
function.
Diets
enriched
neuroactive
ingredients
proposed
support
functions
in
humans.
Several
compounds,
including
ginsenosides,
identified
Panax
ginseng.
Many
studies
show
that
the
roots
this
plant
promote
neuroprotection
neuroplasticity.
Objective:
The
aim
study
was
examine
red
ginseng
cultivated
an
innovative
vertical
farming
technology.
effects
were
investigated
determine
whether
they
could
(1)
plasticity
survival
during
stress
vitro
(2)
improve
(short-term
memory)
vivo.
Methods:
An
extract
Botalys
root
powder
tested
on
primary
hippocampal
cortical
neurons,
injured
or
not,
glutamate.
Its
neuritogenesis
synaptogenesis
as
well
its
neuroprotective
efficacy.
Moreover,
effect
vivo
aged
animals.
Results:
results
demonstrated
prolonged
treatment
neurons
significantly
prompts
synapse
formation
neurite
elongation
cultures
neurons.
In
addition,
protected
from
glutamate-induced
excitotoxicity
a
culture
aging
mice,
oral
administration
for
7
days
improved
short-term
memory
deficit
associated
aging.
Conclusion:
Altogether,
these
indicate
promotes
models
improves
deficits
Keywords:
ginseng,
functions,
vitro,
Language: Английский
Study of anthocyanins in several genetic resources from the national eggplant collection of Armenia
Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426,
Journal Year:
2024,
Volume and Issue:
7(12), P. 636 - 648
Published: Dec. 14, 2024
Background:
The
main
components
of
eggplant
skin
extract
are
anthocyanins,
which
play
a
vital
role
in
determining
the
skin's
color.
Cultivated
eggplants
can
potentially
increase
their
anthocyanin
content
by
crossing
with
various
forms
that
synthesize
different
types
anthocyanins.
This
strategy
could
lead
to
even
higher
antioxidant
properties.
Consuming
products
rich
anthocyanins
is
beneficial
for
preventing
development
serious
diseases.
Therefore,
special
attention
should
be
paid
selection
due
high
these
biologically
active
substances.
Objective:
study
focuses
on
effectiveness
genetic
resources
conserved
at
National
Eggplant
Collection
Armenia,
specifically
examining
fruits.
Methods:
Experiments
were
conducted
experimental
station
Scientific
Centre
Vegetable
and
Industrial
Crops
Darakert,
Ararat
Marz
Armenia
during
2022-2023.
For
experiments,
several
from
Armenian
collection
utilized,
including
brinjal
(Solanum
melongena
L.)
varieties
Mini
Miss
Tavush,
wild
relatives
eggplant,
introduced
Taiwan
species
World
Center
(AVRDC),
namely
Solanum
macrocarpon
incanum.
quantitative
determination
total
was
carried
out
using
pH
differential
spectrophotometry.
data
subjected
two
statistical
processing
methods.
Analysis
Variance
(ANOVA)
Hierarchial
Cluster
Analysis.
Results:
fruits
0,34-6,19(mass%),
standard
deviation
±0.06
±0.42
respectively.
moisture
89,35-92,3
(mass%),
±0,96
±1,7.
They
have
promising
anthocyanin-rich
such
as
L.
(Mini
Tavush),
deceased
Tawan
incanum,
Conclusion:
Several
national
collection,
well
exhibited
content.
These
valuable
crucial
breeding
new
hybrids,
creating
innovative
functional
food.
Keywords:
Language: Английский
Long-term safety study of the highly absorbable curcumin formulation TS-P1 in healthy Japanese adults: a randomized, placebo-controlled, double-blind, parallel-group comparative study
Hyunjin Lee,
No information about this author
Yoshitaka Kuwabara,
No information about this author
Akiko Hirose
No information about this author
et al.
Functional Foods in Health and Disease,
Journal Year:
2024,
Volume and Issue:
14(7), P. 546 - 563
Published: July 26, 2024
Background:
Curcumin,
a
yellow-colored
molecule
derived
from
the
rhizome
of
Curcuma
longa,
has
been
identified
as
bioactive
compound
responsible
for
numerous
pharmacological
activities
turmeric.
However,
its
bioavailability
is
very
low,
limiting
potential.
We
have
developed
novel
curcumin
formulation,
TS-P1,
which
exhibits
an
85.2-fold
higher
than
raw
curcumin.
Objective:
The
aim
this
study
was
to
evaluate
safety
long-term
intake
highly
bioavailable
curcumin,
in
healthy
Japanese
adults.
Methods:
conducted
randomized,
placebo-controlled,
double-blind,
parallel-group
comparison
study.
Ninety
adults
were
assigned
either
placebo
or
TS-P1
group
and
took
150
mg
daily
12
weeks.
Physical
examinations,
blood
analysis,
urinalysis,
medical
examinations
performed
every
4
Results:
There
no
adverse
events
attributed
test
foods
during
period.
mean
change
body
weight
mass
index
(BMI)
at
week
baseline
showed
significantly
greater
reduction
group.
As
there
food
calorie
between
groups
period,
observed
appeared
be
due
effect
through
improved
bioavailability.
Conclusions:
These
results
suggest
that
containing
150mg
safe.
Keyword:
Highly
curcumin;
TS-P1:
Theracurmin
Super;
Body
(BMI);
(UMIN
ID:
UMIN000050377)
Language: Английский