Sedative effects of roasted green tea aroma on autonomic nervous activity, central nervous activity, and subjective mood state in healthy adults

Functional Foods in Health and Disease, Journal Year: 2025, Volume and Issue: 15(1), P. 68 - 87

Published: Jan. 15, 2025

Introduction: To clarify the physiological and psychological effects of roasted green tea aroma, this study examined extract its major aromatic components on autonomic nervous activity, central subjective mood state. Methods: Twenty healthy adults who were not averse to aroma tea, did smoke, display any flu symptoms, receiving drug treatment participated in study. The samples comprised a from Shizuoka first-growth (Test I) three pyrazines, which are main III). pupil miosis rate, peripheral skin temperature, cerebral blood flow measured after 2 min inhalation as evaluations. Subjective state was investigated using questionnaire for evaluation. Results: results showed that significantly increased pupillary rate similar observed with hot water. Furthermore, reduced amount oxygenated hemoglobin prefrontal cortex, suggesting it also has sedative effect system. In evaluation Visual Analog Scale, scores “tension”, “anxiety” while increasing those “mood” “comfort” relative addition, specifically different demonstrated even at room temperature when tested concentrations derived analysis. Conclusion: both differ water suggest these pyrazines play role producing effects, 2,3,5-trimethylpyrazine being most important component. findings exerts system by suppressing sympathetic nerve activity parasympathetic activity.

Language: Английский

---

The benefits of terpenoids as functional foods for the managementof type 2 diabetes mellitus

Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426, Journal Year: 2024, Volume and Issue: 7(7), P. 345 - 347

Published: Aug. 1, 2024

Millions of people worldwide are living with type 2 diabetes, and the numbers rising at an unsustainable rate. Furthermore, many those diabetes suffer from micro macrovascular complications that limit their quality life longevity as well impose a significant financial burden on individuals health systems worldwide. Many reliant oral medications or combination injectable insulin treatment for multiorgan unregulated prolonged states high blood sugar levels. these obstacle to adherence due side effects, which include but not limited gastrointestinal discomfort, headaches, urinary tract infections, hypoglycemia. For uninsured underinsured in United States developing countries, cost is additional determines leads undesirable complications. These drawbacks current pharmacological treatments have led interest research into various bioactive compounds phytochemicals such alkaloids, polyphenols, flavonoids, terpenoids use functional foods mitigate advance diabetes. This editorial focuses aims review certain within subclasses being researched effectiveness treating and, thereby, potential food product.

Language: Английский

---

Effects and medical application of plant-origin polyphenols: A narrative review

Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426, Journal Year: 2024, Volume and Issue: 7(8), P. 375 - 385

Published: Aug. 31, 2024

The impact of oxidative stress in the pathogenesis various diseases is well known. Oxidative occurs when there an imbalance between production reactive oxygen species (ROS) and ability a biological system to detoxify these intermediates or repair resulting damage. Polyphenols, diverse group compounds with antioxidant properties, help reduce damage by ROS. They are abundant fruits, vegetables, tea, coffee, wine, other plant-based foods. mechanisms their activity related regulate cellular signaling pathways, metal chelation, mitochondrial protection, while modulating enzyme exhibiting anti-inflammatory effects. Polyphenols can also through ROS scavenging, direct neutralization, enhancing defenses within cells. It has been established that polyphenols derived from plant do not harm metabolism normal cells, but involved metabolic pathways diseased which high redox sensitivity. Incorporating polyphenol-rich foods into diet beneficial for maintaining overall health reducing risk stress-related diseases. Researchers exploring therapeutic potential as dietary supplements functional medical applications. This review discusses origin, structure, benefits, application medicine food industry. Keywords: biologically active compounds, polyphenols, stress, activity, food.

Language: Английский

---

Comparing the FDA's process for health claim submission and the FFC's guidelines for regulating functional foods

Functional Foods in Health and Disease, Journal Year: 2023, Volume and Issue: 13(9)

Published: Sept. 11, 2023

Health claims are essential for providing accurate information about the relationship between nutrients and health outcomes to consumers. They facilitate informed decision-making support individuals in making healthy dietary choices. The U.S. Food Drug Administration (FDA) regulates guide consumers maintaining practices. on food labels help understand potential benefits associated with specific products make choices aligned their goals. These also promote transparency trust industry by evidence-based information. process of submitting a claim FDA involves complying regulatory requirements robust scientific evidence. Scientific evidence plays crucial role substantiating should be based well-designed clinical trials, epidemiological studies, mechanistic research. Adhering labeling ensures informative presentation labels. Functional Center (FFC) is working theoretical aspects creating ideal functional (FF) as well how these identified special FF While focuses evaluating claims, FFC emphasizes safe effective use foods. Understanding FDA's evaluation FFC's guidelines researchers, manufacturers, policymakers navigate landscape consumer Compliance guidelines, adherence standards, clear communication contribute more health-conscious society.Keywords: outcomes, requirements, foods,

Language: Английский

---

Bioactive Protein and Peptides; A Potential Pharma Ingredient for 21st Century Functional Foods

Nursing & Healthcare International Journal, Journal Year: 2023, Volume and Issue: 7(4)

Published: Jan. 1, 2023

Bioactive peptides have upsurge advancement in food and health domains recent years. This was driven by the understanding of amino acid structure functions plant animal as bioactive peptide sources. The functionality bioactivities are their function -structure relationships. interplay between function-structure protein polypeptides from native state to denature has opened new research waveband much needed innovative ingredient or recipes formulate functional foods on our shelves, however, this is far more important than pharmaceutical drugs but now décor pharma foods. Application for making so develop, utilize, manage population, family individual chronic disease conditions were emphasized. Aligning ingestion peptides, enveloped with circadian rhythm metabolic curves within appropriate time scale enhanced nutrition could maximize absorption, utilization, responses. Hence, use potential societal interventions overall up.

Language: Английский

---

Addressing vitamin D deficiency through nutritional strategies

Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426, Journal Year: 2024, Volume and Issue: 7(6), P. 289 - 301

Published: June 21, 2024

This review explores the multifaceted impacts of vitamin D deficiency on overall health and investigates diverse strategies for addressing this issue. Vitamin presents a global issue with notable implications cardiovascular, immune, brain health. Strategies to address encompass dietary modifications, food fortification, supplementation. Serum 25(OH)D concentration serves as crucial biomarker, levels below 20 ng/mL being indicative deficiency. Tailored supplementation regimens, often favoring D3 its enhanced bioavailability, necessitate careful consideration avoid toxicity risks. The incorporation D-fortified foods into patterns promising systematic approach mitigating promoting Functional Food Center's regulatory process offers structured framework creating products fortified D, emphasizing importance compliance clinical validation. While existing evidence underscores efficacy products, ongoing epidemiological post-market research is imperative fully establish their status functional foods. Keywords: deficiency, intake, supplementation, bioactive compounds,

Language: Английский

---

Red Panax ginseng root promotes neuronal plasticity in vitro and improves cognitive function in aged animals

Functional Foods in Health and Disease, Journal Year: 2024, Volume and Issue: 14(8), P. 574 - 588

Published: Aug. 8, 2024

Background: Cognitive function declines with aging, primarily due to reduced neuronal plasticity, decreased release of trophic factors, and stress. Genetic environmental factors have been shown impact cognitive function. Diets enriched neuroactive ingredients proposed support functions in humans. Several compounds, including ginsenosides, identified Panax ginseng. Many studies show that the roots this plant promote neuroprotection neuroplasticity. Objective: The aim study was examine red ginseng cultivated an innovative vertical farming technology. effects were investigated determine whether they could (1) plasticity survival during stress vitro (2) improve (short-term memory) vivo. Methods: An extract Botalys root powder tested on primary hippocampal cortical neurons, injured or not, glutamate. Its neuritogenesis synaptogenesis as well its neuroprotective efficacy. Moreover, effect vivo aged animals. Results: results demonstrated prolonged treatment neurons significantly prompts synapse formation neurite elongation cultures neurons. In addition, protected from glutamate-induced excitotoxicity a culture aging mice, oral administration for 7 days improved short-term memory deficit associated aging. Conclusion: Altogether, these indicate promotes models improves deficits Keywords: ginseng, functions, vitro,

Language: Английский

---

Study of anthocyanins in several genetic resources from the national eggplant collection of Armenia

Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426, Journal Year: 2024, Volume and Issue: 7(12), P. 636 - 648

Published: Dec. 14, 2024

Background: The main components of eggplant skin extract are anthocyanins, which play a vital role in determining the skin's color. Cultivated eggplants can potentially increase their anthocyanin content by crossing with various forms that synthesize different types anthocyanins. This strategy could lead to even higher antioxidant properties. Consuming products rich anthocyanins is beneficial for preventing development serious diseases. Therefore, special attention should be paid selection due high these biologically active substances. Objective: study focuses on effectiveness genetic resources conserved at National Eggplant Collection Armenia, specifically examining fruits. Methods: Experiments were conducted experimental station Scientific Centre Vegetable and Industrial Crops Darakert, Ararat Marz Armenia during 2022-2023. For experiments, several from Armenian collection utilized, including brinjal (Solanum melongena L.) varieties Mini Miss Tavush, wild relatives eggplant, introduced Taiwan species World Center (AVRDC), namely Solanum macrocarpon incanum. quantitative determination total was carried out using pH differential spectrophotometry. data subjected two statistical processing methods. Analysis Variance (ANOVA) Hierarchial Cluster Analysis. Results: fruits 0,34-6,19(mass%), standard deviation ±0.06 ±0.42 respectively. moisture 89,35-92,3 (mass%), ±0,96 ±1,7. They have promising anthocyanin-rich such as L. (Mini Tavush), deceased Tawan incanum, Conclusion: Several national collection, well exhibited content. These valuable crucial breeding new hybrids, creating innovative functional food. Keywords:

Language: Английский

---

Long-term safety study of the highly absorbable curcumin formulation TS-P1 in healthy Japanese adults: a randomized, placebo-controlled, double-blind, parallel-group comparative study

Functional Foods in Health and Disease, Journal Year: 2024, Volume and Issue: 14(7), P. 546 - 563

Published: July 26, 2024

Background: Curcumin, a yellow-colored molecule derived from the rhizome of Curcuma longa, has been identified as bioactive compound responsible for numerous pharmacological activities turmeric. However, its bioavailability is very low, limiting potential. We have developed novel curcumin formulation, TS-P1, which exhibits an 85.2-fold higher than raw curcumin. Objective: The aim this study was to evaluate safety long-term intake highly bioavailable curcumin, in healthy Japanese adults. Methods: conducted randomized, placebo-controlled, double-blind, parallel-group comparison study. Ninety adults were assigned either placebo or TS-P1 group and took 150 mg daily 12 weeks. Physical examinations, blood analysis, urinalysis, medical examinations performed every 4 Results: There no adverse events attributed test foods during period. mean change body weight mass index (BMI) at week baseline showed significantly greater reduction group. As there food calorie between groups period, observed appeared be due effect through improved bioavailability. Conclusions: These results suggest that containing 150mg safe. Keyword: Highly curcumin; TS-P1: Theracurmin Super; Body (BMI); (UMIN ID: UMIN000050377)

Language: Английский

---