Nationwide seroprevalence of SARS-CoV-2 Delta variant and five Omicron sublineages in companion cats and dogs in the USA: Insights into their role in COVID-19 epidemiology DOI Creative Commons
Subarna Barua, Nneka Vivian Iduu, Daniel Felipe Barrantes Murillo

et al.

Emerging Microbes & Infections, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 5, 2024

Understanding SARS-CoV-2 epidemiology in companion animals is critical for evaluating their role viral transmission and potential as sentinels human infections. This large-scale serosurvey analyzed serum samples from 706 cats 2,396 dogs collected across the USA 2023 using a surrogate virus neutralization test (sVNT) to detect antibodies. Overall, 5.7% of 4.7% tested positive antibodies, with younger (under 12 months) showing significantly lower seropositivity rates (p = 0.0048). Additionally, we 153 variant-specific antibody responses six sVNT kits targeting Delta variant five Omicron sublineages. Among cats, 67.5% showed antibodies Delta, positivity sublineages follows: BA.1 (62.5%), BA.2 (42.5%), BA.4/BA.5 (77.5%), XBB (52.5%), XBB.1.5 (45.0%). In dogs, 55.8% were sublineage (46.0%), (37.2%), (58.4%), (13.3%), (9.7%). Given close contact between humans, persistence against various variants sublineages, our findings suggest that seroprevalence may serve valuable tool tracking COVID-19 epidemiology.

Language: Английский

Assessment of the Risk Impact of SARS-CoV-2 Infection Prevalence between Cats and Dogs in America and Europe: A Systematic Review and Meta-Analysis DOI Creative Commons
Marcos Jessé Abrahão Silva, Davi Silva Santana,

Marceli Batista Martins Lima

et al.

Pathogens, Journal Year: 2024, Volume and Issue: 13(4), P. 314 - 314

Published: April 12, 2024

The COVID-19 pandemic represented a huge obstacle for public health and demonstrated weaknesses in surveillance promotion systems around the world. Its etiological agent, SARS-CoV-2, of zoonotic origin, has been target several studies related to control prevention outbreaks epidemics not only humans but also animals. Domestic animals, such as dogs cats, have extensive contact with can acquire infection both naturally directly from humans. objective this article was summarize seroprevalence findings SARS-CoV-2 cats correlate them strength risk between each them. This is systematic review meta-analysis following recommendations PRISMA 2020. search selection papers carried out using vivo experimental works animals descriptors (MeSH/DeCS) “Animal”, “Public Health”, “SARS-CoV-2” “Pandemic” (together AND) English, Portuguese or Spanish Science Direct, PUBMED, LILACS SciELO databases. ARRIVE checklist used methodological evaluation Comprehensive Meta-Analysis v2.2 software Difference Risk (RD) test evaluate statistical inferences (with subgroups by continent). Cats showed greater susceptibility compared joint analysis (RD = 0.017; 95% CI 0.008–0.025; p < 0.0001) American subgroup 0.053; 0.032–0.073; 0.0001), unlike lack significant difference on European continent 0.009; −0.001–0.018; 0.066). Therefore, it observed that interest due set biological ecological aspects these there are factors influence spread possible spillover events virus thanks anthropozoonotic context.

Language: Английский

Citations

2
A Comprehensive Study of Cellular and Humoral Immunity in Dogs Naturally Exposed to SARS-CoV-2 DOI Creative Commons
Beatriz Davinia Tomeo-Martín, Pablo Delgado-Bonet, Teresa Cejalvo

et al.

Transboundary and Emerging Diseases, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) was identified as the causal agent behind disease 2019 (COVID‐19), a declared pandemic in 2020. Because of zoonotic origin SARS‐CoV‐2 and close contact kept by domestic dogs with their owners, it became imperative to understand role epidemiology virus transmission. In present study, we determined presence described long‐term immune effects 24 exposed environment. Our findings highlight that only subset dogs, naturally SARS‐CoV‐2, exhibit humoral response new (close 17% had IgM antibodies 33% has IgG antibodies). We for first time SARS‐CoV‐2‐specific IFN‐ γ ‐secreting cells (approximately half our dogs). While 56% maintained 8 months, 22% cellular after 4 months. Although some alterations blood parameters proinflammatory cytokines were described, there no evidence indicating an exacerbated cytokine release process. Considering none animals enrolled this study showed viral shedding presented specific responses, is reasonable propose canine system certain companion effective at blocking negative replication, thereby suggesting would not be potential transmitters pathogen other or species could aid promoting collective immunity.

Language: Английский

Citations

1
Pets and SARS-CoV-2: Their role in disease epidemiology DOI
Sandra Barroso‐Arévalo, José Manuel Sánchez‐Vizcaíno

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 171 - 177

Published: Jan. 1, 2024

Language: Английский

Citations

0
SARS-CoV-2 exposure in hunting and stray dogs of southern Italy DOI Creative Commons
Gianmarco Ferrara, Ugo Pagnini, Serena Montagnaro

et al.

Veterinary Research Communications, Journal Year: 2024, Volume and Issue: 48(6), P. 4037 - 4042

Published: Aug. 21, 2024

Abstract Evidence of exposure to the pandemic SARS-CoV-2 has been described in numerous animal species, including pets, which are predisposed coming into contact with this virus due their close relationship owners. It accepted that dogs poorly susceptible and seroconversion, rather than shedding, occurs following infection, can occur directly through infected owners or indirectly environmental contamination. In study, seroprevalence was evaluated apparently health hunting stray Campania region, southern Italy (sampled September 2023). A total 5/112 (4.5%) animals tested seropositive using two different commercial ELISAs. Stray had greater dogs. The feces blood each were a real-time PCR targeting nucleocapsid ORF1ab coding sequences. No positive molecular investigations, indicating past without active infection at time sampling.

Language: Английский

Citations

0
SARS-CoV-2 Secondary Spillover: From Doubt to Evidence DOI Creative Commons
AbdulRahman A. Saied, Faten F. Mohammed, Asmaa A. Metwally

et al.

IntechOpen eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 19, 2024

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the culprit behind disease 2019 (COVID-19) and it believed that bats may have been source. SARS-CoV-2 can naturally infect humans various animal species, including pets, farm animals, zoo wild animals might serve as potential reservoirs for viral transmission to humans. Most infected with are associated exposure humans; therefore, characterized by zoonosis reverse zoonosis. It critical quickly detect classify variants of concern in both domestic animals. In addition, it’s possible novel emerging due mutation, making infection incidental hosts worrying. Here, we discuss most recent information on spreading among humans, importance genomic research, active surveillance these help us understand spread viruses emergence variants.

Language: Английский

Citations

0
Nationwide seroprevalence of SARS-CoV-2 Delta variant and five Omicron sublineages in companion cats and dogs in the USA: Insights into their role in COVID-19 epidemiology DOI Creative Commons
Subarna Barua, Nneka Vivian Iduu, Daniel Felipe Barrantes Murillo

et al.

Emerging Microbes & Infections, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 5, 2024

Understanding SARS-CoV-2 epidemiology in companion animals is critical for evaluating their role viral transmission and potential as sentinels human infections. This large-scale serosurvey analyzed serum samples from 706 cats 2,396 dogs collected across the USA 2023 using a surrogate virus neutralization test (sVNT) to detect antibodies. Overall, 5.7% of 4.7% tested positive antibodies, with younger (under 12 months) showing significantly lower seropositivity rates (p = 0.0048). Additionally, we 153 variant-specific antibody responses six sVNT kits targeting Delta variant five Omicron sublineages. Among cats, 67.5% showed antibodies Delta, positivity sublineages follows: BA.1 (62.5%), BA.2 (42.5%), BA.4/BA.5 (77.5%), XBB (52.5%), XBB.1.5 (45.0%). In dogs, 55.8% were sublineage (46.0%), (37.2%), (58.4%), (13.3%), (9.7%). Given close contact between humans, persistence against various variants sublineages, our findings suggest that seroprevalence may serve valuable tool tracking COVID-19 epidemiology.

Language: Английский

Citations

0