Green Synthesis and Assessment of Antibacterial and Antiobiofilm Activities of Silver Nanoparticles Using Carthumas tinctorius Extract
Research Square (Research Square),
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 9, 2025
Abstract
Silver
nanoparticles
(AgNPs)
synthesized
using
Carthamus
tinctorius
flower
extract
exhibit
significant
biomedical
potential,
particularly
for
their
antibacterial
and
antibiofilm
properties.
Various
characterization
techniques,
including
UV-visible
spectroscopy,
SEM,
TEM,
zeta
FTIR,
XRD,
confirmed
the
successful
biosynthesis
of
AgNPs
with
spherical
shapes,
sizes
ranging
from
20
to
60
nm.
The
spectrum
displayed
a
peak
at
approximately
417
nm,
indicating
AgNP
formation.Invitro
antimicrobial
activity
biosynthesized
was
demonstrated
against
Staphylococcus
haemolyticus,
Escherichia
coli,
Klebsiella
pneumoniae,
Acinetobacter
baumannii
across
different
concentrations
(100
6.25
µg/mL).
Results
showed
concentration-dependent
bacterial
inhibition,
highest
efficacy
observed
100
µg/mL,
especially
E.
coli
A.baumannii(inhibition
zones
16.66
mm
16.33
mm,
respectively).
study
highlights
potential
application
as
bioactive
agents
in
biotechnology
pharmacology.
Language: Английский
Antibacterial Activity of Ciprofloxacin-Based Carbon Dot@Silver Nanoparticle Composites
ACS Omega,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 14, 2025
The
combined
green
synthesis
of
carbon
dots
(CDs)
from
the
hydrothermal
conversion
ciprofloxacin
and
silver
nanoparticles
(AgNPs)
using
sodium
alginate
as
a
reducing
stabilizing
agent
results
in
arrangements
nanostructures
(CD@AgNP
composites)
with
positive
surface
charge
that
electrostatically
interact
Gram-positive
Gram-negative
bacteria
planktonic
form
also
biofilm
forms,
inhibiting
their
growth
adhesion
on
surfaces.
Outstanding
performance
for
CD-based
materials
5-log
reduction
colony-forming
units
(CFU/mL)
E.
coli
after
1
h
treatment
decrease
99.32%
consolidated
S.
aureus.
These
result
intrinsic
fluorescence
CDs
an
overall
eco-friendly
preparation
process
can
be
explored
disinfection
procedures
based
direct
administration
sanitizer
dispersed
aqueous
solution.
This
is
justified
by
adequate
antibiotics
positively
charged
composites
AgNPs,
resulting
nanocomposites
which
prevailing
cationic
effect
facilitates
incorporation
diffusion
into
bacterial
membrane
cells.
Language: Английский
In vivo assessment of topically applied silver nanoparticles on entire cornea: comprehensive FTIR study
Nanotoxicology,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 17
Published: Nov. 12, 2024
Silver
nanoparticles
(AgNPs)
have
gained
attention
in
medicine
for
their
potent
antibacterial,
antiviral,
and
anti-inflammatory
properties.
The
use
of
silver
ophthalmic
solutions
raises
concerns
regarding
potential
toxicity
to
ocular
tissues,
such
as
the
cornea,
conjunctiva,
retina,
which
necessitates
further
assessments
aiding
development
safer
solutions.
This
study
investigates
impact
AgNPs
on
corneal
tissue
using
investigations,
Fourier
transform
infrared
(FTIR)
spectroscopy,
chemometric
analyses.
Three
concentrations
(0.48
µg/mL,
7.2
15.5
µg/mL)
were
topically
applied
twice
daily
10
days,
synthesized
biologically
by
reducing
nitrate
with
almond
kernels
water
extract.
Corneas,
obtained
cutting
2-3
mm
below
ora
serrata,
analyzed
FTIR
spectroscopy
subjected
Results
reveal
AgNPs'
influence
constituents
OH
NH
groups,
affecting
lipids
lipid
saturation
index.
alter
both
bulk
interfacial
water,
leading
changes
hydration
thus
modifying
physico-chemical
extends
environment
around
proteins
lipids,
releasing
bound
from
phospholipids
disrupting
hydrogen
bonding
networks
proteins.
In
conclusion,
can
be
linked
dry
eye
onset.
Language: Английский
Silver Nanoparticle-Infused Bone Cement: Innovations in Orthopedic Biomaterials
International Journal of Scientific Research in Science and Technology,
Journal Year:
2024,
Volume and Issue:
11(6), P. 826 - 840
Published: Dec. 27, 2024
The
integration
of
silver
nanoparticles
(AgNPs)
into
bone
cement
has
emerged
as
a
cutting-edge
approach
to
enhance
the
functional
properties
orthopedic
biomaterials.
Silver
nanoparticles,
known
for
their
broad-spectrum
antimicrobial
properties,
provide
an
innovative
solution
combat
implant-associated
infections.
This
review
delves
synthesis
methods,
including
in
situ
formation
and
physical
blending,
examines
performance
AgNP-infused
terms
efficacy,
mechanical
strength,
biocompatibility.
By
addressing
challenges
such
cytotoxicity
regulatory
considerations,
this
analysis
highlights
its
transformative
potential
reducing
infection
rates,
enhancing
implant
longevity,
ultimately
improving
patient
outcomes
surgeries.
Language: Английский