Brazilian Journal of Pharmaceutical Sciences,
Journal Year:
2022,
Volume and Issue:
58
Published: Jan. 1, 2022
To
assess
the
therapy
relative
to
indication,
effectiveness,
safety
and
adherence
in
patients
with
Alzheimer’s
disease
(AD).
An
interventional,
prospective,
non-randomized
study
was
conducted
a
single
secondary
care
center
Brazil.
The
pharmacist-led
medication
management
(MTM)
detect
drug-related
problems
(DRPs)
at
baseline
after
six
months
of
intervention.
health
status
outcomes
(i.e.
cognitive
screening
tests;
levels
glucose;
total
cholesterol;
triglycerides;
thyroid
stimulating
hormone;
serum
free
thyroxine
blood
pressure)
were
measured.
66
AD
included,
whom
55
completed
follow-up
months.
36
(36/55)
non-adherent
drug
therapy.
Out
detected
166
DRPs,
116
solved.
Four
withdrawn
from
protocol
due
resolution
prodromal
symptoms.
On
conclusion
study,
MTM
improved
controlled
pressure,
glucose,
cholesterol,
triglycerides
(p<0.05).
effective
solving
69.8%
improving
controlling
clinical
parameters
evaluated.
Nursing Older People,
Journal Year:
2024,
Volume and Issue:
36(2), P. 28 - 33
Published: Jan. 24, 2024
Polypharmacy
and
inappropriate
prescribing
of
psychotropic
medicines
are
common
among
people
living
with
dementia
pose
considerable
health
risks.
One
way
addressing
these
issues
is
by
involving
the
person
their
carer
in
shared
decision-making.
This
article
discusses
some
related
to
polypharmacy
examines
concept
decision-making
this
context.
The
author
details
practical
aids
that
nurses
other
healthcare
professionals
can
use
engage
carers
about
use.
International Journal of Pharmacy Practice,
Journal Year:
2024,
Volume and Issue:
32(5), P. 377 - 383
Published: July 2, 2024
Abstract
Objectives
Previous
studies
have
examined
the
psychological
burden
of
caregivers
patients
with
dementia.
However,
although
many
struggle
to
assist
dementia
medication
management,
relationship
between
assisting
such
taking
their
medicines
and
caregiver
is
understudied.
Therefore,
this
study
identified
association
caregivers’
medication.
Methods
A
cross-sectional
survey
was
conducted
among
in
Japan.
The
questionnaire
included
questions
that
assessed
symptoms
dementia,
status
through
assistance
from
caregivers,
using
Kessler
Psychological
Distress
Scale
Japanese
version
Perceived
Stress
Scale.
Key
findings
total
57
participated
study.
Higher
scores
were
significantly
associated
unsuccessful
regular
(β
=
0.35,
95%
confidence
interval
[CI]:
2.23–12.0,
P
<
.05),
depressive
0.26,
CI:
0.10–8.53,
irritability
0.38,
2.71–11.5,
.05).
Likewise,
higher
on
0.37,
1.87–12.5,
.05)
Conclusion
suggest
for
Journal of patient-centered research and reviews,
Journal Year:
2024,
Volume and Issue:
11(2), P. 97 - 106
Published: July 16, 2024
Numerous
studies
have
demonstrated
that
dementia
is
associated
with
increased
utilization
of
health
care
services,
which
in
turn
results
costs
care.
Dementia
Lewy
bodies
(DLB)
greater
relative
to
other
forms
due
higher
rates
hospitalization
and
nursing
home
placement
directly
related
neuropsychiatric
symptoms,
parkinsonism,
susceptibility
delirium,
elevated
caregiver
burden.
There
a
critical
need
for
researchers
identify
potentially
modifiable
factors
contributing
poor
clinical
outcomes
patients
DLB,
may
include
comorbidities,
polypharmacy/contraindicated
medications,
access
specialty
Previous
research
has
utilized
Medicare
claims
data,
limiting
the
ability
study
early-onset
(ie,
prior
age
65)
DLB.
Integrated
systems
offer
combine
electronic
medical
record
data
Medicare,
Medicaid,
commercial
therefore
be
ideal
this
population.
The
goals
narrative
review
are
1)
synthesize
describe
current
literature
on
2)
highlight
gaps
literature,
3)
provide
recommendations
stakeholders,
including
researchers,
systems,
policymakers.
It
important
improve
understanding
among
DLB
inform
public
policies
decision-making,
as
will
ultimately
quality
patient
Journal of Alzheimer s Disease,
Journal Year:
2020,
Volume and Issue:
73(3), P. 1253 - 1264
Published: Jan. 2, 2020
Background:
The
global
prevalence
of
Alzheimer’s
disease
(AD)
and
its
treatment
costs
are
projected
to
increase
significantly,
placing
increasing
pressure
on
health
systems
create
new
models
care.
Community
pharmacists
well-positioned
provide
medication
management
for
people
with
AD.
In
Arabic-speaking
countries,
little
is
known
about
pharmacists’
knowledge
practices
in
caring
Objective:
To
evaluate
community
AD
management,
counseling
skills,
dispensing
patterns
when
their
caregivers
the
United
Arab
Emirates
(UAE).
Methods:
A
large-scale
cross-sectional
survey
was
conducted
three
cities
UAE
using
stratified
random
sampling.
questionnaire
comprised
validated
tools
measure
open-ended
questions.
logistic
regression
model
predict
comprehensiveness.
Results:
total
325
completed
questionnaire.
mean
scores
pharmacotherapy
were
57.0%
67.6%,
respectively.
Major
shortcomings
identified;
history-taking,
adherence
assessment,
provided
by
2.2%,
9.3%,
17.3%,
minority
comprehensive
counselling;
multivariate
analysis
yielded
insights
into
pharmacist
characteristics
associated
such
counseling.
Conclusion:
Pharmacists
did
not
structured
patient-centered
care
adequate
counseling,
assess
adherence-related
issues
appropriately,
had
deficient
knowledge.
develop
pharmacy-based
services
communities,
a
multifaceted
approach
required
that
goes
beyond
improving
pharmacy
workforce
communication
skills
address
broader
sociocultural,
legislative,
financial
factors.
BMC Geriatrics,
Journal Year:
2023,
Volume and Issue:
23(1)
Published: Oct. 20, 2023
Older
adults
living
with
dementia
may
express
challenging
responsive
behaviours.
One
management
strategy
is
pharmacologic
treatment
though
these
options
often
have
limited
benefit,
which
lead
to
multiple
treatments
being
prescribed.The
aim
of
the
present
study
was
describe
psychoactive
medication
polypharmacy
and
explore
factors
associated
in
a
cohort
older
Nova
Scotia,
Canada,
including
gender-stratified
analysis.
This
retrospective
those
aged
65
years
or
recorded
diagnosis
between
2005
2015.
Medication
dispensation
data
collected
from
April
1,
2010,
(cohort
entry)
either
death
March
31,
2015
exit).
Psychoactive
claims
were
captured.
defined
as
presence
three
more
prescription
medications
dispensed
one
subject
overlapping
for
than
30
days.
episodes
described
duration,
quantity,
implicated
medications.
Regression
analysis
examined
experience
frequency
polypharmacy.
All
stratified
by
gender.The
included
15,819
(mean
age
80.7
years;
70.0%
female),
99.4%
(n
=
15,728)
receiving
at
least
over
period
follow-up.
19.3%
cohort.
The
gender
specific
logistic
regressions
demonstrated
that
both
men
women
younger
an
increased
risk
(women:
OR
0.97,
95%CI[0.96,
0.98],
men:
0.96,
95%CI[0.95,
0.97]).
Men
less
likely
if
their
location
residence
urban
(OR
0.86,
95%CI[0.74,
0.99]).
There
no
significant
association
(urban
rural)
dementia.
Antidepressants
most
class,
while
quetiapine
medication.This
suggests
ages
rural
locations
benefit
access
non-pharmacological
management.
The Senior Care Pharmacist,
Journal Year:
2021,
Volume and Issue:
36(10), P. 508 - 522
Published: Oct. 1, 2021
Objective:
To
describe
two
pharmacist-led
initiatives
aimed
to
reduce
potentially
inappropriate
medication
(PIM)
use
in
community-dwelling
patients
with
dementia
or
cognitive
impairment.
Design:
Retrospective,
descriptive
analysis
of
clinical
initiatives.
Setting:
Academic
geriatric
primary
care
clinics.
Participants:
Patients
were
included
if
they
received
a
Memory
Clinic
pharmacist
review
May
1,
2017,
December
31,
2019,
Living
Dementia
(LWD)
program
November
15,
2018
2019
provider
follow-up
within
6
months.
Interventions:
Both
involved
by
identify
and
make
recommendations
regarding
medications
that
may
contribute
The
served
concerns
impairment;
whereas,
the
LWD
enrolled
an
established
diagnosis
dementia.
Main
Outcome
Measure:
Number
PIMs
could
negatively
impact
cognition
each
cohort.
Additionally,
6-month
implementation
rates
analyzed
for
actionable
recommendations.
RESULTS:
(n
=
110)
taking
average
2.4
PIMs;
40)
1.5
PIMs.
Six-month
all
61.0%
42.4%
program.
Specifically
evaluating
deprescribing
recommendations,
PIM
discontinuation
rate
was
63.6%
group
60.0%
group.
Conclusion:
Pharmacists
routinely
identified
during
reviews,
which
led
successful
recommendation
throughout
multiple
stages
decline.
programs
will
continue
be
adapted
ensure
maximal
impact.
Journal of Pharmacy Practice and Community Medicine,
Journal Year:
2020,
Volume and Issue:
6(1), P. 05 - 09
Published: April 30, 2020
Aim:
The
study
is
aimed
to
assess
public
perception,
awareness,
expectations
and
experiences
towards
the
role
of
community
pharmacists
(CPs)
in
Quetta
City,
Pakistan.
Methods:
This
was
a
questionnairebased,
cross-sectional
survey.
Keeping
aim
mind,
questionnaire
developed
by
research
team
through
mutual
consensus,
experience
sharing
extensive
literature
review.
By
using
an
online
calculator,
423
respondents
were
approached
conveniently
for
data
collection.
SPSS
v.20.0
used
coding
analysis.
Based
on
objectives
study,
descriptive
statistics
applied
Results:
mean
age
30.61±9.95
males
dominated
group
(318,
75.2%).
Eighty-one
percent
agreed
that
CPs
provide
consultation
how
medicine
works,
identify
prevent
errors
are
good
explaining
things
their
level
understanding.
Nearly
70%
expected
take
personal
responsibility
resolving
drug-related
problems,
educate
them
about
appropriate
use
medicines
monitor
response
drug
therapy.
All
positive
when
they
asked
from
CPs.
Respondents
reliable
source
information
important
healthcare
professionals
(80.4
77.3%
respectively).
Counseling
endorsed
60%
while
held
responsible
problems.
Conclusion:
Although
findings
revealed
certain
limitations,
had
attitudes,
constructive
also
indicated
consumer
preferences
evolution
pharmacist
professional
services
PLoS ONE,
Journal Year:
2024,
Volume and Issue:
19(7), P. e0305991 - e0305991
Published: July 22, 2024
Before
extending
the
range
of
services
provided,
maximizing
usefulness
current
procedures
within
community
pharmacy
settings
is
needed,
as
scope
evolving
in
different
dimensions.
The
present
study
aims
to
assess
degree
factors
affecting
satisfaction
traditional
using
population
data
collected
from
patients
attending
academic
and
public
healthcare
centers
Jordan.
A
validated,
pretested,
adapted
survey
instrument
has
been
utilized
contemporary
delivered
by
pharmacists
Linear
regression
analysis
evaluated
predictors
associated
with
higher
total
scores
services.
included
642
centers.
Different
dimension
scores,
such
explanation
consideration,
scored
similarly,
values
ranging
64.5%
-
69.7%
maximum
possible
score.
mean
scale
score
was
67.2%
scores.
Using
linear
analysis,
respondents
who
were
satisfied
their
treatment
plans
likely
have
increased
number
prescription
medications
age
lower
Results
indicated
that
policymakers
might
be
confident
setting;
however,
there
always
room
for
more
robust
quality
control
activities.