Journal of Biomolecular Structure and Dynamics, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 12
Published: Dec. 18, 2024
Plant-derived bioactive substances have demonstrated significant qualities that suggest they may be crucial in preventing various chronic diseases. Flavonoids, which include apigenin, are the biggest group of polyphenols. In our study, we aimed to obtain methanol-chloroform (1:1) extract from aerial parts
Language: Английский
Process Biochemistry, Journal Year: 2024, Volume and Issue: 143, P. 234 - 247
Published: May 6, 2024
Language: Английский
Citations
6
Turkish Journal of Biodiversity, Journal Year: 2024, Volume and Issue: 7(1), P. 20 - 31
Published: May 15, 2024
Secondary metabolites in plants, identifying, quantifying, and determining the biological activity of plants enables use different fields such as pharmacology, food, cosmetics. Different chromatographic methods GC-MS/MS (volatile compounds, fatty acid) LC-MS/MS (phenolic compounds) are used to identify quantify these secondary metabolites. Silybum marianum is a member Asteraceae family grows naturally. It known among public by names Thistle, Virgin Mary Thorn, Milky Kengel. In this study, S. hexane extract was analyzed GC-MS/MS, methanol-chloroform (1:1 v/v) LC-MS/MS. Palmitic acid methyl ester (17.96%), linoleic (14.20%), sesquicineole (10.22%) were determined GC-MS/MS. Moreover, analysis resulted quantification chlorogenic (250.171 µg/g extract), salicylic (234.95 isoquercitrin (210.65 rutin (102.05 extract). According results, palmitic detected main components phenolic compound respectively. Molecular docking applied determine their interaction with urease enzyme. calculated MolDock score -104.63, -113.21, binding energies -3.70, -6.50 kcal/mol may be enzyme inhibitor.
Language: Английский
Citations
5
International Journal of Secondary Metabolite, Journal Year: 2025, Volume and Issue: 12(1), P. 146 - 157
Published: Jan. 19, 2025
Essential oils are widely used in pharmacology, cosmetics, and food industries, they also have biological activities such as antioxidant, anti-inflammatory, anti-rheumatic, antimicrobial. Ocimum basilicum (basil) plant has a rich content of essential oils. Hence, the stem, leaf, flower parts O. were analyzed freshly on RSH/GC-MS device to determine oil content. As result analysis, α-elemene, linalool, eucalyptol detected main components. It was observed that highest linalool part at 47.85%, leaf 44.00%. Additionally, it determined α-elemene with 12.49%. According analysis results, high amounts eucalyptol, detected. The inhibitory properties these compounds against DNA gyrase enzyme investigated by molecular docking. MolDock score (-78.72, -47.50, -88.86) binding energy (2.9, 4.6, 4.0 kcal/mol) respectively. ADME/T molecules examined; did not show any toxic effects. result, compound may be an inhibitor enzyme. In addition, can contribute economy obtaining from non-consumable flowers stem basil increasing its usability industries cleaning, etc.
Language: Английский
Citations
0
Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, Journal Year: 2025, Volume and Issue: 28(3), P. 636 - 649
Published: May 1, 2025
In this study, the phytochemical and biological activities of Rosa canina (RC) R. pimpinellifolia (RP) fruit methanol extracts were investigated. HPLC analysis revealed that RP RC contained high amounts ascorbic acid gallic as major components. GC-MS/MS analysis, oleic acid, linoleic palmitic methyl ester most abundant compounds in both extracts. The total phenolic contents 17.28±0.10 5.19±0,22 mg GAE/g extract, respectively. DPPH˙ scavenging (13.45±0.21 µg/mL for 3.41±0.05 RP) observed to be higher than (42.15±1.35 µg/mL). reducing power capacities 55.57±3.23 87.24±2.44 µg/mL, According BSA denaturation assay, anti-inflammatory effect was found more effective at low doses with DFS similar doses. extract showed xanthine oxidase (XO) inhibition an IC50 value 2.28±0.25 µg/mL. binding affinities XO determined 6.20 6.60 kcal/mol, addition, molecular dynamics simulations complexes applied 100 ns stable. Binding energies by performing MM/PBSA, it recorded a level 21.50 kcal/mol. way, constituents two different rosehip species compared, ideas their use food, cosmetics, medicine presented.
Language: Английский
Citations
0
Genetic Resources and Crop Evolution, Journal Year: 2025, Volume and Issue: unknown
Published: May 9, 2025
Language: Английский
Citations
0
Journal of Scientific Reports-A, Journal Year: 2024, Volume and Issue: 057, P. 144 - 152
Published: May 21, 2024
In this study, content analyses of the products obtained by pyrolysis and extraction walnut shells were performed with some advanced analytical methods such as GS-MS, LC/MS-MS, FTIR. LC-MS/MS analyses. The presence phenolic compounds in liquid extract was determined using 41 standards. analysis results compared, it found that type amount extracted more than liquid. As a result standards investigations, total 10 liquids detected 2 these 8 compounds, catechin (770.75 µg/g extract), hydroxy benzaldehyde (140.78 vanillic acid (114.95 compounds) extract. existence supported FTIR two different processes. By GC-MS analysis, linoleic methyl ester (44.01%), stearic (14.93%), palmitic (24.67%), linolenic shell showed (18.97%), (18.10%), o-xylene (12.17%), o-ethyl toluene (8.14%) formed pyrolysis. findings revealed product contain very phenolic, acid, compounds. A concrete about use study areas.
Language: Английский
Citations
1
Current Perspectives on Medicinal and Aromatic Plants (CUPMAP), Journal Year: 2024, Volume and Issue: unknown
Published: May 10, 2024
Nanoparticles are structures that applicable to a wide range of fields. The most significant characteristic these is their structural and dimensional diversity, which varies the synthesis process based on area will be incorporated into several sections. Although there other synthetic techniques, green technique often used. By employing only natural processes instead chemicals, this method synthesizes products leaving no by-products. also highly preferred as it affordable. In respect, approach was utilized in study investigate characteristics, phytochemical content, evaluate antibacterial activity silver nanoparticles from black pepper (Lavandula stoechas), commonly used sweetener food beverages. Furthermore, theoretical investigation conducted glucosamine-6-phosphate synthase inhibitory characteristics resveratrol molecule, identified main constituent HPLC outcome. Characterization tools like FT-IR, UV-Vis, fluorescence spectroscopy were employed. content examined by HPLC.
Language: Английский
Citations
0
Bütünleyici ve Anadolu Tıbbı Dergisi, Journal Year: 2024, Volume and Issue: 5(2), P. 10 - 24
Published: Aug. 30, 2024
The genus Achillea L. belongs to Asteraceae, the largest family of vascular plants. species is a medicinal plant widely used in traditional medicine due bioactive compounds it contains that are distributed worldwide. In this study, we aimed examine biological activity potential plants by analyzing phytochemical content two growing on land Iğdır University campus. volatile and phenolic contents flower, stem-leaf parts A. biebersteinii millefolium harvested different periods were determined chromatographic methods (GC-MS/MS LC-MS/MS). As result GC-MS analysis, was observed presence high levels eucalyptol (43.22%) harvest time dramatically changed rates components LC-MS/MS analysis showed main constituent all materials chlorogenic acid. addition, component, acid interactions with xanthine oxidase enzyme silico molecular docking. Chlorogenic interaction calculated binding energies (-8.0 kcal/mol) MolDock score (-130.96).
Language: Английский
Citations
0
Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Journal Year: 2024, Volume and Issue: 14(4), P. 1636 - 1644
Published: Oct. 1, 2024
In this study, the contents of both extraction liquid and pyrolysis products chestnut shells were characterized using Gas Chromatography-Mass Spectrometry (GC-MS), Liquid (LC/MS-MS) Fourier Infrared Spectroscopy (FT-IR). LC-MS/MS analyses; sample samples obtained from different processes determined 41 phenolic standards. The results analysis showed that type amount compounds in extract significantly higher than those liquid. According to results, very valuable such as catechin (2526.96 µg/g extract), gallic acid (175.02 protocatechuic (76.47 extract) high amounts. FTIR by two was performed. GC-MS revealed stearic methyl ester (28.78%), palmitic (27.81%) o-xylene (9.29%) extract. However, amounts linoleic acid, (32.45%), (23.06%) linolenic oleic (11.32%) detected compared normal content. All these findings show processing method physicochemical conditions are important obtaining organic acids plant bark.
Language: Английский
Citations
0
Journal of Biomolecular Structure and Dynamics, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 12
Published: Dec. 18, 2024
Plant-derived bioactive substances have demonstrated significant qualities that suggest they may be crucial in preventing various chronic diseases. Flavonoids, which include apigenin, are the biggest group of polyphenols. In our study, we aimed to obtain methanol-chloroform (1:1) extract from aerial parts
Language: Английский
Citations
0