Annals of Medicine and Surgery,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 16, 2024
Introduction:
The
present
study
employs
bioinformatics
tools
to
identify
shared
upregulated
genes
between
chemical
burns
and
gastric
cancer.
Methods:
GEO
retrieved
gene
sets
for
this
investigation.
GSEs
with
P
-value
<0.05
LOG
fold
change
(FC)
>1
were
valid
upregulated.
Gastric
cancer
burn
common
elevated
found
using
Venn
diagram
online
tools.
In
the
second
stage,
“string”
visualized
network,
non-coding
RNAs
deleted,
“interaction”
was
examined
choose
important
nodes.
Next,
they
explored
String
gene-interaction
network
genes.
To
determine
most
interacting
genes,
Gephi
(V
0.9.7)
used
“betweenness
centrality”
>
“0”
evaluate
twenty-gene
network.
TISIDB
drug
banks
provide
gene-related
medications.
Results:
study,
two
including
ALOX5AP
SERPINB2,
obtained,
highest
centrality
among
Additionally,
current
presented
five
drugs,
Urokinase,
Tenecteplase,
DG031,
AM103,
Fiboflapon,
which
can
have
predicted
effects
on
following
burns.
Conclusion:
According
in-silicon
analyses,
SERPINB2
are
linked
genetic
keys
Considering
that
is
an
environmental
factor
leads
upregulation
of
thus,
be
related
incidence
International Wound Journal,
Journal Year:
2024,
Volume and Issue:
21(2)
Published: Feb. 1, 2024
Abstract
The
primary
objective
of
this
systematic
review
and
meta‐analysis
was
to
ascertain
the
prevalence
anxiety
identify
associated
risk
factors
among
individuals
who
have
suffered
burn
injuries.
We
conducted
a
thorough
search
across
various
international
electronic
databases,
including
Scopus,
PubMed
Web
Science,
as
well
Persian
databases
like
Iranmedex
scientific
information
database
(SID).
Our
encompassed
period
from
earliest
available
records
up
8
August
2023.
employed
keywords
derived
Medical
Subject
Headings
(MeSH)
such
“Prevalence”,
“Anxiety”
“Burns”.
In
total,
2586
patients
participated
in
13
cross‐sectional
studies.
mean
age
participants
32.88
(SD
=
2.51).
compilation
studies,
documented
overall
occurrence
rate
stood
at
16.1%
(95%
CI:
10.0%
24.7%;
I
2
93.138%;
p
<
0.001).
outcomes
meta‐regression
analysis,
which
examined
association
between
year
publication,
did
not
uncover
any
significant
correlation
(
0.442).
Furthermore,
there
notable
gender,
TBSA
affected,
educational
level
types
Therefore,
healthcare
providers
need
recognize
substantial
fundamental
consideration.
This
recognition
should
prompt
proactive
approach
toward
early
detection
timely
intervention.
Developing
personalized
intervention
strategies
tailored
each
patient's
unique
needs
is
paramount.
These
may
encompass
range
therapeutic
options
counselling,
psychotherapy
or
consultations
with
mental
health
specialists.
Journal of Nursing Reports in Clinical Practice,
Journal Year:
2024,
Volume and Issue:
0(0), P. 0 - 0
Published: April 15, 2024
Burn
injury
patients
often
experience
a
range
of
psychological
challenges,
such
as
pain,
anxiety,
and
depression.
In
this
context,
nurses
have
crucial
responsibility
in
caring
for
clients
with
mood
disorders.
the
current
study,
authors
aim
to
provide
comprehensive
perspective
on
nursing
role
during
post-burn
disorders
among
burn
by
reviewing
previous
evidence
literature.
A
literature
search
was
conducted
PubMed
Scopus
databases
using
following
key
terms
"burns",
"severe
burns",
"mood
disorders",
"nursing".
The
desire
focused
papers
related
burns,
disorders,
nursing.
20
studies
were
selected
review.
Nurses
play
managing
conditions
like
depression,
post-traumatic
stress
disorder
(PTSD),
anxiety.
Their
responsibilities
include
early
detection,
holistic
assessment,
intervention
addressing
patients'
emotional
well-being.
Educating
families,
providing
support,
creating
therapeutic
environment
are
critical
aspects
care.
work
demystify
conditions,
encourage
mental
health
engagement,
implement
personalized
care
plans.
By
reducing
stress,
promoting
well-being,
facilitating
access
services,
contribute
significantly
survivors'
recovery
quality
life.
Nursing’s
integral
PTSD,
anxiety
is
crucial.
compassionate,
that
meets
diverse
needs
survivors,
guiding
them
toward
recovery.
Research Square (Research Square),
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 27, 2025
Abstract
Background
Amputation
resulting
from
diabetes
remains
a
significant
public
health
challenge
in
Ghana,
often
leading
to
increased
morbidity
and
mortality.
Nurses
serve
as
frontline
healthcare
providers
managing
these
patients.
Aim
This
qualitative
study
explores
nurses'
experiences
challenges
diabetic
amputations
at
the
Sunyani
Teaching
Hospital
Ghana.
Methods
Using
phenomenological
approach,
semi-structured
interviews
were
conducted
with
13
nurses
working
surgical
units
of
(STH)
between
April
2024
July
2024.
Results
The
identified
three
key
themes
regarding
nurses’
amputations:
emotional
psychological
challenges,
physical
resource
constraints,
recommendations
for
improvement.
Findings
indicate
that
face
burdens,
limitations,
difficulties
patient–nurse
relationships,
developing
coping
mechanisms
while
caring
patients
diabetes-related
amputations.
Conclusion
findings
provide
valuable
insights
into
faced
by
suggest
strategies
improving
care
delivery
outcomes
individuals
Recommendation
To
enhance
patient
outcomes,
recommend
improved
training,
better
allocation,
interdisciplinary
collaboration.
Additionally,
there
is
need
structured
mental
support
programs
emotionally
taxing
situations.
Emphasis
also
placed
on
incorporating
specialized
wound
training
national
nursing
curriculum.
Pakistan Journal of Health Sciences,
Journal Year:
2025,
Volume and Issue:
unknown, P. 137 - 141
Published: March 31, 2025
Physiotherapy
prevents
contractures
and
aids
mobility
in
pediatric
burn
patients.
Objective:
To
evaluate
the
potential
benefits
of
implementing
early
orthotic
interventions
physiotherapy
programs
patients
with
injuries.
Methods:
This
quasi
experimental
study
was
conducted
on
27
children
at
Department
Physical
Medicine
Rehabilitation
(PM
R),
The
Children
Hospital
University
Child
Health
Sciences,
Lahore
between
August
2022
2023.
sample
size
included
Convenient
sampling
technique
used
to
collect
data.
under
age
16
years
were
study.
ROM
(measured
via
a
goniometer),
muscle
tone
(assessed
using
Ashworth
scale),
strength
(evaluated
Oxford
scale
MMT)
systematically
assessed.
Related
pre-treatment
questionnaire
filled
first,
they
undergoing
rehabilitation
protocol
(anti-contracture
positioning,
ROM,
casting,
splinting,
stretching)
followed
by
verbal
filling
after
3months.
Wilcoxon
Signed
Rank
Test
measure
difference
before
intervention.
Results:
Muscle
majority
tested
which
possible
against
gravity
now
some
resistance.
Result
suggest
that
activities
like
carrying
an
object
other
ADLs
severe
difficult
improved.
limited
intervention
partially
limited.
Conclusions:
In
conclusion,
amalgamation
orthosis
represented
pivotal
cornerstone
comprehensive
care
paradigm
for
patients,
yielding
myriad
positive
effects
significantly
enhance
their
journey.
Annals of Medicine and Surgery,
Journal Year:
2024,
Volume and Issue:
unknown
Published: April 16, 2024
Introduction:
Burn
injuries
lead
to
dysregulation
of
immune
molecules,
impacting
cellular
and
humoral
pathways.
This
study
aims
determine
the
prediction
molecules
activity
during
burn
wound
healing
among
elderly
patients.
Methods:
The
current
utilized
Gene
Expression
Omnibus
(GEO)
database
extract
proper
gene
set.
Also,
literature
review
was
conducted
in
present
find
signatures.
used
“enrich
r”
website
identify
biological
functions
extracted
genes.
critical
modules
related
mortality
were
identified
using
weighted
co-expression
network
analysis
(WGCNA)
R
package.
Results:
appreciated
GSE
extracted.
According
data,
most
upregulated
signatures
Natural
Killer
(NK)
Cells,
downregulated
associated
with
M1
macrophages.
results
WGCNA
have
shown
that
(
P
<107
score
0.17)
investigated,
100
first
genes
Additionally,
enrich
r
has
demonstrated
pathways,
including;
process,
including
regulation
histamine
secreted
from
mast
cell
<0.05),
T
helper
17
differentiation
autophagy
<0.05)
obtained.
Finally,
by
analysis,
“B3GNT5”
obtained
(degree>ten
“betweenness
centrality”>30
considered).
Conclusion:
significant
changes
macrophage
NK
expression
patterns
post-burn
injury,
linking
them
potential
improvements
clinical
outcomes
healing.
B3GNT5,
mortality,
highlighted
as
a
key
marker
for
prognostic
evaluation.
