Insect Science, Journal Year: 2024, Volume and Issue: unknown
Published: July 21, 2024
Language: Английский
Current Biology, Journal Year: 2024, Volume and Issue: 34(4), P. R158 - R173
Published: Feb. 1, 2024
Plants have been an essential source of human medicine for millennia. In this review, we argue that a holistic, interdisciplinary approach to the study medicinal plants combines methods and insights from three key disciplines - evolutionary ecology, molecular biology/biochemistry, ethnopharmacology is poised facilitate new breakthroughs in science, including pharmacological discoveries rapid advancements health well-being. Such research leverages data spanning space, time, species associated with plant evolution, genomics, metabolomic trait diversity, all which build heavily on traditional Indigenous knowledge. contrasts sharply most well-funded successful during last half-century, which, despite notable advancements, has greatly oversimplified dynamic relationships between humans, kept hidden larger narratives about these relationships, overlooked potentially important into life-saving medicines. We suggest people should be viewed as partners whose relationship involves complicated poorly explored set (socio-)ecological interactions not only domestication but also commensalisms mutualisms. short, are just chemical factories extraction exploitation. Rather, they may symbiotic shaped modern societies, improved health, extended lifespans.
Language: Английский
Citations
21
Published: April 9, 2024
The use of herbaria for science and conservation is revolutionizing the discovery, exploration, protection biodiversity at unprecedented scopes scales. Global Metaherbarium—a digitally interlinked, open-access resource—is stimulating these efforts helping to facilitate massive investigations that utilize aggregated digital derivatives physical herbarium specimens. Simultaneously, growing this virtual resource expanding collections by researchers from many scholarly domains who increasingly are sampling specimens multiomic (e.g., genomics, transcriptomics, metabolomics, proteomics, microbiomics). These leading new scientific insights supporting development actions, but they come with a substantial cost: (partial) destruction priceless often irreplaceable specimens, which constitute global heritage should be permanently safeguarded future reference. absence comprehensive set “best practices” destructively leads confusion uncertainty institutions alike risks over-exploitation precious when research executed. Here, we provide best practices aimed reducing uncertainties creating framework sustainably ethically Our recommendations intended two complementary overlapping audiences—users stewards—who together build, use, protect collections.
Language: Английский
Citations
3
Nature Ecology & Evolution, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 27, 2024
Language: Английский
Citations
2
Molecular Ecology Resources, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 28, 2024
ABSTRACT Low coverage ‘genome‐skims’ are often used to assemble organelle genomes and ribosomal gene sequences for cost‐effective phylogenetic barcoding studies. Natural history collections hold invaluable biological information, yet poor preservation resulting in degraded DNA hinders polymerase chain reaction‐based analyses. However, it is possible generate libraries sequence the short fragments typical of genome‐skims from museum collections. Here we introduce a snakemake toolkit comprised three pipelines skim2mito , skim2rrna gene2phylo designed unlock genomic potential historical specimens using genome skimming. Specifically, perform batch assembly, annotation analysis mitochondrial nuclear genes, respectively, low‐coverage skims. The third pipeline takes set alignments performs individual partitioned concatenated based on trees. We benchmark our with simulated data, followed by testing novel skimming dataset both recent solariellid gastropod samples. show that can recover genes poorly preserved family Solariellidae, consistent current understanding taxonomic relationships. generation bioinformatic facilitate processing large quantities data vast repository held natural will greatly aid species discovery exploration biodiversity over time, ultimately aiding conservation efforts face changing planet.
Language: Английский
Citations
1
bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown
Published: Aug. 14, 2023
Abstract Low coverage “genome-skims” are often used to assemble organelle genomes and ribosomal gene sequences for cost effective phylogenetic barcoding studies. Natural history collections hold invaluable biological information, yet poor preservation resulting in degraded DNA hinders PCR based analyses. However, with improvements molecular techniques sequencing technology, it is possible use methods developed working ancient generate libraries sequence the short fragments typical of genome skims from museum collections. Here we introduce a snakemake toolkit comprised three pipelines skim2mt , skim2rrna gene2phylo designed unlock genomic potential historical specimens using skimming. Specifically, perform batch assembly, annotation analysis mitochondrial nuclear genes, respectively, low-coverage skims. The third pipeline takes set alignments performs individual partitioned concatenated on trees. We benchmark our simulated data, followed by testing novel skimming dataset both recent solariellid gastropod samples. show that can recover genes poorly preserved family Solariellidae. In addition, multiple consistent current understanding taxonomic relationships. generation bioinformatic facilitate processing large quantities data vast repository held natural will greatly aid species discovery exploration biodiversity over time, ultimately aiding conservation efforts face changing planet.
Language: Английский
Citations
2
Insect Science, Journal Year: 2024, Volume and Issue: unknown
Published: July 21, 2024
Language: Английский
Citations
0