IntechOpen eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 5, 2024
Beta Thalassemia Major is a severe inherited blood disorder caused by mutations in the HBB gene, resulting reduced or absent production of beta-globin chains. This condition leads to chronic anemia, requiring regular transfusions and iron chelation therapy. The prevalent regions such as Mediterranean, Middle East, South Asia, Southeast Asia. Advances molecular diagnostics, including PCR non-invasive prenatal testing, have significantly improved early detection treatment outcomes. Screening prevention programs high-risk areas number affected births. use artificial intelligence specific diagnostic areas, particularly managing overload, also being explored enhance patient care. chapter covers genetic structure, clinical manifestations, methods, overload management Major.
Language: Английский