Recent Advances in Allergic Rhinitis: A Narrative Review

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 4, 2024

Allergic rhinitis (AR) is a prevalent chronic respiratory condition characterized by nasal inflammation, sneezing, congestion, and itching, significantly impacting quality of life. Over recent years, considerable advancements have been made in understanding the pathophysiology, diagnosis, management AR. This narrative review aims to synthesize these developments, providing comprehensive overview key areas. Emerging insights into AR pathophysiology elucidated complex interplay between genetic predisposition, environmental factors, immune system dysregulation. Notably, role epithelial barrier microbiome pathogenesis has garnered increasing attention, offering potential targets for novel therapies. Advances diagnostic technologies, such as component-resolved diagnostics molecular allergology, enhanced precision allergy identification, enabling more personalized treatment approaches. In terms management, significant progress pharmacological non-pharmacological treatments. Novel biologics targeting specific pathways involved AR, including monoclonal antibodies against immunoglobulin (Ig)E interleukin (IL)-4/13, shown promise reducing symptoms refractory cases. Additionally, there resurgence interest strategies, allergen avoidance, immunotherapy, complementary therapies, which offer holistic options patient care. The integration digital health tools mobile applications further empowered patients, allowing real-time symptom tracking adjustments. Recent guidelines emphasize multidisciplinary approach promoting integrated care models that involve collaboration allergists, primary providers, other specialists. These also highlight importance patient-centered care, advocating shared decision-making tailored plans based on individual profiles. conclusion, landscape allergic rapidly evolving, with ongoing research innovation paving way improved outcomes. underscores staying abreast advances optimize life individuals affected rhinitis.

Language: Английский

Comorbidities of allergic rhinitis in children

Clinical and Experimental Pediatrics, Journal Year: 2024, Volume and Issue: unknown

Published: July 31, 2024

Language: Английский