Eosinophils: old cells, new directions

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 11

Published: Jan. 16, 2025

Eosinophils are polymorphonuclear cells that have progressively gained attention due to their involvement in multiple diseases and, more recently, various homeostatic processes. Their well-known roles range from asthma and parasitic infections less prevalent such as eosinophilic granulomatosis with polyangiitis, esophagitis, hypereosinophilic syndrome. In recent years, biological therapies targeting these been developed, altering the course of pathologies. Recent research has demonstrated differences eosinophil subtypes functions. The presence distinct classes eosinophils led theory resident (rEos) inflammatory (iEos). Subtype determined by pattern protein expression on cell membrane localization eosinophils. Most this conducted murine models, but several studies confirm findings peripheral blood tissue. objective review is provide a comprehensive analysis eosinophils, divide line into two populations different functions purposes.

Language: Английский

The Potential Mechanisms of Extracellular Vesicles in Transfusion-Related Adverse Reactions: Recent Advances

Transfusion Clinique et Biologique, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Association between eosinophil number and overweight status: a nonlinear, bidirectional study

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: May 10, 2025

Language: Английский