Electrospun Nanofibers for the Delivery of Endolysin/Dendronized Ag-NPs Complex Against Pseudomonas aeruginosa DOI Creative Commons
Magdalena Lasak, Małgorzata Łysek-Gładysińska, Karolina Lach

et al.

Nanotechnology Science and Applications, Journal Year: 2025, Volume and Issue: Volume 18, P. 57 - 70

Published: Feb. 1, 2025

As bacterial resistance to antibiotics increases, there is an urgent need identify alternative antibacterial agents and improve materials. One the controlled transport of that prevents infection with drug-resistant bacteria, especially in treatment difficult-to-heal wounds. This work presents use electrospun PLCL/PVP (poly(L-lactide-co-ε-caprolactone/polyvinylpyrrolidone) nanofibers modified two properties but different mechanisms action, is, dendritic silver nanoparticles (Dend-AgNPs) endolysin. The nanomat prepared this manner showed significant activity against antibiotic-resistant Pseudomonas aeruginosa strains, inhibiting their growth production key pigments virulence factors. Moreover, as carriers selected factors significantly reduced cytotoxicity towards human fibroblasts. results confirmed possibility using presented product innovative dressing material, opening new perspectives for wounds combating infections bacteria.

Language: Английский

Surface modification of cellulose nanocrystals for biomedical and personal hygiene applications DOI
Bantamlak Birlie Kassie,

Muluken Jemberie Getahun,

Aklilu Azanaw

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 136949 - 136949

Published: Oct. 28, 2024

Language: Английский

Citations

5

Recent advances in innovative biomaterials for promoting bladder regeneration: processing and functionalization DOI Creative Commons
Yi Zhang, Fei Ding,

Junjie Han

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 12

Published: Jan. 6, 2025

The bladder is a dynamic organ located in the lower urinary tract, responsible for complex and important physiological activities human body, including collecting storing urine. Severe diseases or injuries often lead to tissue destruction loss of normal function, requiring surgical intervention reconstruction. rapid development innovative biomaterials has brought revolutionary opportunities modern urology overcome limitations transplantation. This article first summarized latest research progress processing approaches functionalization acellular matrix, hydrogels, nanomaterials, porous scaffolds repairing reconstructing structure function damaged bladder. Then, we discussed emerging strategies regeneration functional recovery, such as cell therapy, organoids, etc. Finally, outlined issues future prospects inspire directions. By reviewing these technologies, hope provide appropriate insights achieve ultimate goal designing manufacturing artificial substitutes with ideal performance all aspects.

Language: Английский

Citations

0

Influence of Graphene, Hydroxyapatite, and Hydroxyapatite‐Niobium Pentoxide Nanoparticles on Polycaprolactone Electrospun Fibers Mats Properties DOI Open Access
Elisângela Guzi de Moraes, Karina Luzia Andrade, Luiz Fernando Belchior Ribeiro

et al.

Journal of Applied Polymer Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 15, 2025

ABSTRACT Polycaprolactone (PCL) electrospun fiber mats containing varying concentrations of graphene flakes (GF), hydroxyapatite (HAp), and with niobium pentoxide (HAp5Nb) were successfully prepared by electrospinning. These composites exhibit great potential in biomedical applications, particularly as scaffolds for bone tissue engineering. The addition GF enhances the rheological properties PCL solution due to intrinsic resulting from their interactions. Additionally, incorporating HAp HAp5Nb nanoparticles increases viscosity PCL‐based solutions, leading formation thinner diameters. GF, HAp, characterized using transmission electron microscopy (TEM) x‐ray diffractometry (XRD), while degree disorder heterogeneity was assessed Raman spectroscopy. physical chemical also scanning (SEM), XRD, fourier‐transform infrared spectroscopy (FTIR), contact angle measurements. cytotoxicity evaluated mouse fibroblasts. Results showed that cell viability 100% extract higher than pure or Dulbecco's modified Eagle's medium DMEM control, indicating samples non‐toxic promoted growth. This highlights

Language: Английский

Citations

0

An Overview of Potential Applications of Environmentally Friendly Hybrid Polymeric Materials DOI Open Access
Raluca Nicoleta Darie-Niţă, Stanisław Frąckowiak

Polymers, Journal Year: 2025, Volume and Issue: 17(2), P. 252 - 252

Published: Jan. 20, 2025

The applications of polymeric materials are being constantly reviewed and improved. In the present world, word hybrid, general idea combining two or more inherently different approaches, designs, is gaining significant attention. area sustainable with a low environmental impact also rapidly evolving many new discoveries, including use natural origin countless combinations thereof. This review tries to summarize current state knowledge about hybrid their special attention that can be considered “environmentally friendly”. As application field quite broad, was limited following topics: packaging, medical applications, sensors, water purification, electromagnetic shielding. Furthermore, this points out prospects challenges for mentioned in terms creating novel solutions nano micro-materials mostly renewable origin.

Language: Английский

Citations

0

Electrospun Nanofibers for the Delivery of Endolysin/Dendronized Ag-NPs Complex Against Pseudomonas aeruginosa DOI Creative Commons
Magdalena Lasak, Małgorzata Łysek-Gładysińska, Karolina Lach

et al.

Nanotechnology Science and Applications, Journal Year: 2025, Volume and Issue: Volume 18, P. 57 - 70

Published: Feb. 1, 2025

As bacterial resistance to antibiotics increases, there is an urgent need identify alternative antibacterial agents and improve materials. One the controlled transport of that prevents infection with drug-resistant bacteria, especially in treatment difficult-to-heal wounds. This work presents use electrospun PLCL/PVP (poly(L-lactide-co-ε-caprolactone/polyvinylpyrrolidone) nanofibers modified two properties but different mechanisms action, is, dendritic silver nanoparticles (Dend-AgNPs) endolysin. The nanomat prepared this manner showed significant activity against antibiotic-resistant Pseudomonas aeruginosa strains, inhibiting their growth production key pigments virulence factors. Moreover, as carriers selected factors significantly reduced cytotoxicity towards human fibroblasts. results confirmed possibility using presented product innovative dressing material, opening new perspectives for wounds combating infections bacteria.

Language: Английский

Citations

0