Bioprinting of hepatic tissue using 3D technology: Transitioning beyond laboratory models to real-world applications in medical treatments

Applied Materials Today, Journal Year: 2024, Volume and Issue: 39, P. 102307 - 102307

Published: July 8, 2024

Language: Английский

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Impact of Heterogeneity in Liver Matrix and Intrahepatic Cells on the Progression of Hepatic Fibrosis

Tissue and Cell, Journal Year: 2024, Volume and Issue: 91, P. 102559 - 102559

Published: Sept. 14, 2024

Language: Английский

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Hydrogel-Based Strategies for Liver Tissue Engineering

Chem & Bio Engineering, Journal Year: 2024, Volume and Issue: 1(11), P. 887 - 915

Published: Sept. 24, 2024

The liver's role in metabolism, detoxification, and immune regulation underscores the urgency of addressing liver diseases, which claim millions lives annually. Due to donor shortages transplantation, tissue engineering (LTE) offers a promising alternative. Hydrogels, with their biocompatibility ability mimic extracellular matrix (ECM), support cell survival function LTE. This review analyzes recent advances hydrogel-based strategies for LTE, including decellularized hydrogels, natural polymer-based synthetic hydrogels. These materials are ideal vitro culture obtaining functional hepatocytes. Hydrogels' tunable properties facilitate creating artificial models, such as organoids, 3D bioprinting, liver-on-a-chip technologies. developments demonstrate hydrogels' versatility advancing LTE's applications, hepatotoxicity testing, regeneration, treating acute failure. highlights transformative potential hydrogels LTE implications future research clinical practice.

Language: Английский

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Biomimetic injectable hydrogels of gelatin and hyaluronic acid for hepatic cell culture

Published: July 26, 2024

Language: Английский

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