Effect of Ti6Al4V Alloy Surface and Porosity on Bone Osseointegration: In Vivo Pilot Study in Rabbits DOI Open Access
Amparo Vanaclocha, Vicente Vanaclocha, Carlos Atienza

et al.

Materials, Journal Year: 2025, Volume and Issue: 18(9), P. 2141 - 2141

Published: May 6, 2025

Unmodified Ti6Al4V can osseointegrate, but sometimes this capacity needs to be improved. This study aimed see how much porosity improves osseointegration in a implant. Three types of cylindrical-shaped implants (13.00 mm length × 5.00 diameter) were evaluated: solid sandblasted acid-etched, sintered, and porous 3D-printed (681.00 µm average pore size). Fifteen 20-week-old nullipara female parasite-free New Zealand California white rabbits used, employing the femoral condyle defect model undertaking µ-CT analysis pull-out testing eight weeks later. On densitometric analysis, rod showed highest new bone growth around Bone was higher inside for (54.00 ± mm3) than sintered (1.00 0.05 zero implants. In test, there no statistically significant differences ANOVA between (900.00 N 310.00 N) (700.00 220.00 Such did exist material (220.00 50.00 two other materials (sintered p 0.002, 0.034). The implant strength significantly better that Still, first two.

Language: Английский

Additively Manufactured Biomedical Ti-15Mo Alloy with Triply Periodical Minimal Surfaces and Functional Surface Modification DOI Creative Commons

Zerui Li,

Jingyuan Xu, Jincheng Tang

et al.

Metals, Journal Year: 2025, Volume and Issue: 15(4), P. 355 - 355

Published: March 24, 2025

Ti and alloys are being widely used as bone tissue repair materials. Progress on mechanical properties bio-functionality is required for their applications due to the large difference in elastic modulus between implants fact that materials themselves biologically inert. In this work, a low-modulus, β-phase Ti-15Mo alloy based triply periodical minimal surfaces (TPMS) structure was fabricated using Powder Bed Fusion-Laser Beam (PBF-LB) under optimized printing parameters into implant samples with controllable porous structures. The selection of TPMS, lattice unit cell size, relative density combination cytocompatibility. Surface modifications were further impart antibacterial, antioxidant, osteogenesis implants. Broad-spectrum antibacterial Ag, antioxidant tannic acid (TA), highly stable fluorinated hydroxyapatite ((F)HA) applied an advanced coating microporous TiO2 surface modification layer formed by micro-arc oxidation. Ultimately, biofunctional obtained Young’s 15–50 GPa, yield strength approximately 100 MPa, good cytocompatibility, hemocompatibility, bactericidal effects. This study provides systematic scheme preparation β subsequent studies.

Language: Английский

Citations

0
Effect of Ti6Al4V Alloy Surface and Porosity on Bone Osseointegration: In Vivo Pilot Study in Rabbits DOI Open Access
Amparo Vanaclocha, Vicente Vanaclocha, Carlos Atienza

et al.

Materials, Journal Year: 2025, Volume and Issue: 18(9), P. 2141 - 2141

Published: May 6, 2025

Unmodified Ti6Al4V can osseointegrate, but sometimes this capacity needs to be improved. This study aimed see how much porosity improves osseointegration in a implant. Three types of cylindrical-shaped implants (13.00 mm length × 5.00 diameter) were evaluated: solid sandblasted acid-etched, sintered, and porous 3D-printed (681.00 µm average pore size). Fifteen 20-week-old nullipara female parasite-free New Zealand California white rabbits used, employing the femoral condyle defect model undertaking µ-CT analysis pull-out testing eight weeks later. On densitometric analysis, rod showed highest new bone growth around Bone was higher inside for (54.00 ± mm3) than sintered (1.00 0.05 zero implants. In test, there no statistically significant differences ANOVA between (900.00 N 310.00 N) (700.00 220.00 Such did exist material (220.00 50.00 two other materials (sintered p 0.002, 0.034). The implant strength significantly better that Still, first two.

Language: Английский

Citations

0