The role of epigenetics in plant pathogens interactions under the changing environments; A systematic review

Plant Stress, Journal Year: 2025, Volume and Issue: unknown, P. 100753 - 100753

Published: Jan. 1, 2025

Language: Английский

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Unlocking Plant Resilience: Advanced Epigenetic Strategies Against Heavy Metal and Metalloid Stress

Plant Science, Journal Year: 2024, Volume and Issue: unknown, P. 112265 - 112265

Published: Sept. 1, 2024

Language: Английский

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Population-level annotation of lncRNAs in Arabidopsis reveals extensive expression variation associated with transposable element–like silencing

The Plant Cell, Journal Year: 2023, Volume and Issue: 36(1), P. 85 - 111

Published: Sept. 8, 2023

Abstract Long noncoding RNAs (lncRNAs) are understudied and underannotated in plants. In mammals, lncRNA loci nearly as ubiquitous protein-coding genes, their expression is highly variable between individuals of the same species. Using Arabidopsis thaliana a model, we aimed to elucidate true scope transcription across plants from different regions study its natural variation. We used transcriptome deep sequencing data sets spanning hundreds accessions several developmental stages create population-wide annotation lncRNAs, revealing thousands previously unannotated loci. While genome, most appear be actively silenced extremely accessions. This high variability largely caused by repressive chromatin levels at High was particularly common for intergenic lncRNAs (lincRNAs), where pieces transposable elements (TEs) present 50% these lincRNA associated with increased silencing variation, such tend targeted TE machinery. created improve our understanding plant genome biology, raising fundamental questions about what causes genome.

Language: Английский

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Testing the potential of zebularine to induce heritable changes in crop growth and development

Theoretical and Applied Genetics, Journal Year: 2025, Volume and Issue: 138(1)

Published: Jan. 1, 2025

Abstract Key message Zebularine-treated wheat uncovered a phenotype with characteristics of an epigenetically regulated trait, but major chromosomal aberrations, not DNA methylation changes, are the cause, making zebularine unsuitable for epigenetic breeding. Breeding to identify disease-resistant and climate-tolerant high-yielding wheats has led yield increases over many years, new hardy, higher yielding varieties still needed improve food security in face climate change. Traditional breeding develop cultivars is lengthy process taking more than seven years from initial cross cultivar release. The speed can be enhanced by using modern technologies including high-throughput phenomics, genomic selection, directed mutation via CRISPR. Here we test concept modifying gene regulation transiently disrupting methyltransferase inhibitor, (Zeb), as means uncover novel phenotypes elite facilitate controlled traits. development architecture inflorescence, spikelet density, important component yield, both grain size number have been extensively modified during domestication cultivars. We identified several Zeb-treated plants dominant that increased density compared untreated controls. Our analysis showed addition causing loss methylation, Zeb treatment resulted abnormalities, trisomy formation telocentric chromosome. provide evidence copy gene, Q , most likely cause two plants. Collateral damage chromosomes suggests this viable approach

Language: Английский

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Epigenetics in evolution and adaptation to environmental challenges: pathways for disease prevention and treatment

Epigenomics, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 17

Published: Feb. 13, 2025

Adaptation to challenging environmental conditions is crucial for the survival/fitness of all organisms. Alongside genetic mutations that provide adaptive potential during challenges, epigenetic modifications offer dynamic, reversible, and rapid mechanisms regulating gene expression in response changes both evolution daily life, without altering DNA sequences or relying on accidental favorable mutations. The widespread conservation diverse – like methylation, histone modifications, RNA interference across species, including plants underscores their significance evolutionary biology. Remarkably, environmentally induced alterations are passed daughter cells inherited transgenerationally through germline cells, shaping offspring phenotypes while preserving memory. Throughout anthropoid evolution, have played roles in: i) suppressing transposable elements viral genomes intruding into host genome; ii) inactivating one X chromosomes female balance dosage; iii) imprinting ensure from parental allele; iv) functional alleles compensate dysfunctional ones; v) modulating epigenome transcriptome influence gut microbiome among other functions. Understanding interplay between factors processes may valuable insights developmental plasticity, dynamics, disease susceptibility.

Language: Английский

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Genome-wide association study (GWAS) provides insights into the genomic basis of reproduction-related traits in Chouardia litardierei (Asparagaceae)

BMC Plant Biology, Journal Year: 2025, Volume and Issue: 25(1)

Published: May 2, 2025

Chouardia litardierei, commonly known as amethyst meadow squill, is a plant species characterized by profound ecological plasti vcity. As wild, non-model species, it represents suitable system for gaining insights into the genomic background of local adaptation process. By implementing genome-environment and genome-wide association studies, we sought to investigate regions related development several reproduction-related traits in C. litardierei: sexual reproduction, Average Height Inflorescences (AHI) Total Flower Count (TFC) per genotype, asexual Bulb (BC) genotype. A (GEA) study selected litardierei populations revealed precipitation coldest quarter bioclimatic variable with most substantial influence on detected variability, numerous candidate genes functionally characterized. To evaluate genetic basis combined phenotypic data 214 individuals raised part common garden experiment ddRADseq genotyping results. After various single- multi-locus GWAS models all traits, multiple loci affecting their were recognized. In addition, high, narrow-sense heritability estimates indicated that factors accounted over 55% variance each trait. Notably, highest estimate was observed (71.95%), suggesting its crucial role reproductive success. Functional annotation associated identified key protein families involved biological pathways, including nitrogen metabolism, phytohormone regulation, floral organs development. GEA GWAS, list significantly specific environmental variables morphological reproduction litardierei. These findings provide foundation deeper understanding molecular mechanisms driving processes occurring among from different habitat types. At same time, high further underscore significance

Language: Английский

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Environmental Adaptation of Genetically Uniform Organisms with the Help of Epigenetic Mechanisms—An Insightful Perspective on Ecoepigenetics

Epigenomes, Journal Year: 2022, Volume and Issue: 7(1), P. 1 - 1

Published: Dec. 26, 2022

Organisms adapt to different environments by selection of the most suitable phenotypes from standing genetic variation or phenotypic plasticity, ability single genotypes produce in environments. Because near identity, asexually reproducing populations are particularly for investigation potential and molecular underpinning latter alternative depth. Recent analyses on whole-genome scale differently adapted clonal animals plants demonstrated that epigenetic mechanisms such as DNA methylation, histone modifications non-coding RNAs among pathways supporting plasticity is used stably Case studies revealed habitat-specific fingerprints were maintained over subsequent years pointing at existence ecotypes. Environmentally induced epimutations corresponding gene expression changes provide an ideal means fast directional adaptation changing new conditions, because they can synchronously alter many population members. microorganisms inclusive human pathogens also exploit epigenetically mediated environmental adaptation, this phenomenon considered a universal biological principle. The production same sequence response cues provides mechanistic explanation “general-purpose genotype hypothesis” “genetic paradox invasions”.

Language: Английский

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Exploring the patterns of evolution: Core thoughts and focus on the saltational model

Biosystems, Journal Year: 2024, Volume and Issue: 238, P. 105181 - 105181

Published: March 11, 2024

Language: Английский

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Phenotypic lags influence rapid evolution throughout a drought cycle

Evolution, Journal Year: 2024, Volume and Issue: 78(6), P. 1067 - 1077

Published: March 15, 2024

Climate anomalies are increasing and posing strong selection, which can lead to rapid evolution. This is occurring on a backdrop of interannual variability that might weaken or even reverse selection. However, the effect climatic evolution rarely considered. We study differences contribute throughout 7-year period, encompassing severe drought across 12 populations Mimulus cardinalis (scarlet monkeyflower). Plants were grown in common greenhouse environment under wet dry treatments, where specific leaf area date flowering measured. examine association between trait values different climate metrics at time periods, including collection year, prior years, cumulative sequential years. Of variables we assessed, find mean annual precipitation best describe over our period. Past climates, 1-2 years prior, often related conflicting direction collection-year climate. Uncovering these complex impacts critical better predict interpret change.

Language: Английский

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Genomic and Epigenomic Influences on Resilience across Scales: Lessons from the Responses of Fish to Environmental Stressors

Integrative and Comparative Biology, Journal Year: 2024, Volume and Issue: 64(3), P. 853 - 866

Published: April 15, 2024

Understanding the factors that influence resilience of biological systems to environmental change is a pressing concern in face increasing human impacts on ecosystems and organisms inhabit them. However, most considerations have focused at community ecosystem levels, whereas here we discuss how including consideration processes occurring lower levels organization may provide insights into higher levels. Specifically, explore genomic epigenomic cascade up We ask concepts "resistance," or capacity system minimize response disturbance, "recovery," ability return its original state following disturbance avoid tipping points resulting regime shifts, map these organization. Overall, suggest substantial changes be required support using selected examples responses fish climate-change-related stressors such as high temperature hypoxia genome, epigenome, organism.

Language: Английский

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