Evidence that extracellular HSPB1 contributes to inflammation in alcohol-associated hepatitis DOI
Anne-Marie C. Overstreet,

McKenzie Burge,

Annette Bellar

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 6, 2024

Alcohol-associated hepatitis (AH) is the most life-threatening form of alcohol-associated liver disease (ALD). AH characterized by severe inflammation attributed to increased levels ethanol, microbes or microbial components, and damage-associated molecular pattern (DAMP) molecules in liver. HSPB1 (Heat Shock Protein Family B (Small) Member 1; also known as Hsp25/27) a DAMP that rapidly released from cells experiencing stress, including hepatocytes. The goal this study was define role pathophysiology.

Language: Английский

Evidence that extracellular HSPB1 contributes to inflammation in alcohol-associated hepatitis DOI
Anne-Marie C. Overstreet,

McKenzie Burge,

Annette Bellar

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 6, 2024

Alcohol-associated hepatitis (AH) is the most life-threatening form of alcohol-associated liver disease (ALD). AH characterized by severe inflammation attributed to increased levels ethanol, microbes or microbial components, and damage-associated molecular pattern (DAMP) molecules in liver. HSPB1 (Heat Shock Protein Family B (Small) Member 1; also known as Hsp25/27) a DAMP that rapidly released from cells experiencing stress, including hepatocytes. The goal this study was define role pathophysiology.

Language: Английский

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