Optical Materials, Journal Year: 2024, Volume and Issue: unknown, P. 116596 - 116596
Published: Dec. 1, 2024
Language: Английский
Optical Materials, Journal Year: 2024, Volume and Issue: unknown, P. 116596 - 116596
Published: Dec. 1, 2024
Language: Английский
Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 343, P. 122443 - 122443
Published: July 2, 2024
Language: Английский
Citations
4Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(8), P. 969 - 969
Published: July 23, 2024
Lung cancer is the leading cause of cancer-related mortality worldwide, largely due to limited efficacy anticancer drugs, which primarily attributed insufficient doses reaching lungs. Additionally, patients undergoing treatment experience severe systemic adverse effects distribution drugs non-targeted sites. In light these challenges, there has been a growing interest in pulmonary administration for lung cancer. This route allows be delivered directly lungs, resulting high local concentrations that can enhance antitumor while mitigating toxic effects. However, poses challenge overcoming mechanical, chemical, and immunological defenses respiratory tract prevent inhaled drug from properly penetrating To overcome drawbacks, use nanoparticles inhaler formulations may promising strategy. Nanoparticles assist minimizing clearance, increasing penetration into epithelium, enhancing cellular uptake. They also facilitate increased stability, promote controlled release, delivery target sites, such as tumor environment. Among them, chitosan-based demonstrate advantages over other polymeric nanocarriers their unique biological properties, including activity mucoadhesive capacity. These properties have potential when administered via route. view above, this paper provides an overview research conducted on drug-loaded incorporated devices Furthermore, article addresses emerging technologies, siRNA (small interfering RNA), context therapy. Particularly, recent studies employing are described.
Language: Английский
Citations
4Separation and Purification Technology, Journal Year: 2024, Volume and Issue: 354, P. 129320 - 129320
Published: Aug. 23, 2024
Language: Английский
Citations
4Food Hydrocolloids, Journal Year: 2024, Volume and Issue: 160, P. 110722 - 110722
Published: Oct. 11, 2024
Language: Английский
Citations
4Optical Materials, Journal Year: 2024, Volume and Issue: unknown, P. 116596 - 116596
Published: Dec. 1, 2024
Language: Английский
Citations
4