Hydrogel-based Soft Robotics for Surgical Machinery DOI
Tuğra Alp Terzi

Next generation., Journal Year: 2024, Volume and Issue: 8(1), P. 89 - 89

Published: Nov. 15, 2024

Hydrogel-based soft robotics represent a transformative approach in surgical machinery, offering unparalleled adaptability, biocompatibility, and precision for minimally invasive procedures. Hydrogels, with their high water content tunable mechanical properties, mimic biological tissues, making them ideal applications delicate environments. This research explores the integration of hydrogel materials into robotic systems, focusing on fabrication, actuation mechanisms, performance applications. Key advancements include development stimuli-responsive hydrogels that enable precise control movement force, enhancing capability to navigate complex anatomical structures. The study also examines computational models simulating behavior optimizing designs. While potential benefits hydrogel-based improving patient outcomes are significant, challenges remain ensuring durability, scalability, reliable systems. aims address these limitations by integrating advanced science engineering. By doing so, it contributes evolution technologies, paving way safer more effective

Language: Английский

New Perspectives of Hydrogels in Chronic Wound Management DOI Creative Commons

Adina Alberts,

Ana‐Maria Bratu, Adelina-Gabriela Niculescu

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(3), P. 686 - 686

Published: Feb. 4, 2025

Chronic wounds pose a substantial healthcare concern due to their prevalence and cost burden. This paper presents detailed overview of chronic emphasizes the critical need for novel therapeutic solutions. The pathophysiology wound healing is discussed, including stages factors contributing chronicity. focus on diverse types wounds, such as diabetic foot necrosis, pressure ulcers, venous leg highlighting etiology, consequences, issues they provide. Further, modern care solutions, particularly hydrogels, are highlighted tackling challenges management. Hydrogels characterized multipurpose materials that possess vital characteristics like capacity retain moisture, biocompatibility, incorporation active drugs. Hydrogels’ effectiveness in applications demonstrated by how support healing, preserving ideal moisture levels, promoting cellular migration, possessing antibacterial properties. Thus, this hydrogel technology’s latest developments, emphasizing drug-loaded stimuli-responsive underscoring these advanced formulations greatly improve therapy outcomes enabling dynamic focused reactions environment. Future directions research promote development customized treatments digital health tools treatment wounds.

Language: Английский

Citations

6
Microgel with a Core—Shell Particulate Structure Formed via Spinodal Decomposition of a Diblock Ionomer Containing a Doped Hydrophobic Moiety DOI Creative Commons
David Julius, Jim Yang Lee, Liang Hong

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(4), P. 231 - 231

Published: March 22, 2025

This study explored the formation of soft colloidal particles from a diblock ionomer (DI) with monomeric composition (acrylonitrile)x-co-(glycidyl methacrylate)y-b-(3-sulfopropyl methacrylate potassium)z—abbreviated as (AxGy)Sz, where x >> z > y. A dispersion was generated by introducing water into pre-prepared DMSO solutions DI, which led to micelle and subsequent coagulation. The assembly hydrophobic (AxGy) blocks influenced content chain conformational flexibility (the ability adopt various forms conformation). resulting microgel structure (in particle form) consists coagulated micelles characterized discrete internal gel domains continuous external hydrophilic layers. Characterization methods included light scattering, zeta potential analysis, size distribution measurements. In contrast, copolymer chains form random coil aggregates in DMSO–H2O mixtures, displaying packing state distinct aforementioned. Additionally, amphiphilic glycidyl (G) units within block were found modulate dimensions. Notably, nanoscale hydrogel corona exhibits high accessibility reactive species aqueous media. typical has spherical shape diameter ranging 50 120 nm. It −65 mV neutral medium; however, it may precipitate if metastable cannot be maintained. Its properties could tailored through adjusting conformation, highlighting its for diverse applications.

Language: Английский

Citations

0
Light‐Actuated, Tunable Micromachines from Photo‐Swellable Colloidal Ionogels DOI

Dezhou Cao,

Jingru Xu,

Dongqing He

et al.

Small, Journal Year: 2025, Volume and Issue: unknown

Published: May 29, 2025

Abstract Active colloids that release ions hold potential for building micromachines capable of dynamically responding to environmental stimuli. Harnessing light precisely regulate and fine‐tune their performance is essential unlocking versatility expanding range applications. To address this challenge, light‐actuated, tunable are developed based on photo‐swellable colloidal ionogels—an azobenzene‐modified co‐polymer microsphere infused with azobenzene‐based ionic liquids (Azo‐ILs)—that undergo reversible cis‐trans isomerization under UV/visible light. UV irradiation increases the ionogel's hydrophilicity causes it swell by H 2 O, releasing Azo‐ILs into aqueous environments a rapid photoresponse (milliseconds), while visible stops swelling. The dissociated lead diffusiophoresis diffusioosmosis, enabling two functionalities: isotropic ion from ionogel pumps water outward exclusion zones up 30 µm, anisotropic partially coated microspheres leads micromotors at speeds ≈3 µm s −1 lifetime ≈15 min. Importantly, magnitude these interactions modulated intensity azobenzene content in co‐polymers. Finite element Brownian dynamics simulations validate electrokinetic mechanisms underlying pump motor's operation. This work establishes platform designing potentially useful fluid manipulation, drug delivery, soft robotics.

Language: Английский

Citations

0
Imidazole-Stabilized Gold Nanoclusters as Photocatalytic Initiator and Crosslinker to Fabricate Functional Hydrogel DOI
Qianling Cui, Ning Yang, Fang Gong

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0
Imidazole-stabilized gold nanoclusters as photocatalytic initiator and crosslinker to fabricate functional hydrogel DOI
Ning Yang, Fang Gong, Hean Zhang

et al.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2024, Volume and Issue: unknown, P. 135408 - 135408

Published: Sept. 1, 2024

Language: Английский

Citations

0
Hydrogel-based Soft Robotics for Surgical Machinery DOI
Tuğra Alp Terzi

Next generation., Journal Year: 2024, Volume and Issue: 8(1), P. 89 - 89

Published: Nov. 15, 2024

Hydrogel-based soft robotics represent a transformative approach in surgical machinery, offering unparalleled adaptability, biocompatibility, and precision for minimally invasive procedures. Hydrogels, with their high water content tunable mechanical properties, mimic biological tissues, making them ideal applications delicate environments. This research explores the integration of hydrogel materials into robotic systems, focusing on fabrication, actuation mechanisms, performance applications. Key advancements include development stimuli-responsive hydrogels that enable precise control movement force, enhancing capability to navigate complex anatomical structures. The study also examines computational models simulating behavior optimizing designs. While potential benefits hydrogel-based improving patient outcomes are significant, challenges remain ensuring durability, scalability, reliable systems. aims address these limitations by integrating advanced science engineering. By doing so, it contributes evolution technologies, paving way safer more effective

Language: Английский

Citations

0