Exosome-Based Sensor: A Landmark of the Precision Cancer Diagnostic Era DOI
Swarup Sonar, Asmit Das,

Lee Yeong Zher

et al.

ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown

Published: May 14, 2025

Extracellular vesicles are nanoscale released by a diversity of cells that mediate intercellular communication transporting an array biomolecules. They gaining increasing attention in cancer research due to their ability carry specific biomarkers. This characteristic makes them potentially useful for highly sensitive, noninvasive diagnostic procedures and more precise prognostic assessments. Consequently, EVs emerging as transformative tool treatment, facilitating early detection personalized medicine. Despite significant progress, clinical implementation is hindered challenges EV isolation, purification, characterization. However, developing advanced biosensor technologies offers promising solutions these obstacles. review highlights recent progress biosensors analysis, focusing on various sensing modalities including optical, electrochemical, microfluidic, nanomechanical, biological sensors. We also explore techniques characterization, such electron microscopy, atomic force nanoparticle tracking single-particle analysis. Furthermore, the critically assesses associated with put forward future directions, aiming usher cutting-edge era precision medicine through advanced, sensor-based, diagnosis detecting EV-carried

Language: Английский

Exosome-Based Sensor: A Landmark of the Precision Cancer Diagnostic Era DOI
Swarup Sonar, Asmit Das,

Lee Yeong Zher

et al.

ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown

Published: May 14, 2025

Extracellular vesicles are nanoscale released by a diversity of cells that mediate intercellular communication transporting an array biomolecules. They gaining increasing attention in cancer research due to their ability carry specific biomarkers. This characteristic makes them potentially useful for highly sensitive, noninvasive diagnostic procedures and more precise prognostic assessments. Consequently, EVs emerging as transformative tool treatment, facilitating early detection personalized medicine. Despite significant progress, clinical implementation is hindered challenges EV isolation, purification, characterization. However, developing advanced biosensor technologies offers promising solutions these obstacles. review highlights recent progress biosensors analysis, focusing on various sensing modalities including optical, electrochemical, microfluidic, nanomechanical, biological sensors. We also explore techniques characterization, such electron microscopy, atomic force nanoparticle tracking single-particle analysis. Furthermore, the critically assesses associated with put forward future directions, aiming usher cutting-edge era precision medicine through advanced, sensor-based, diagnosis detecting EV-carried

Language: Английский

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