Acute kidney injury in patients with COVID-19 compared to those with influenza: a systematic review and meta-analysis DOI Creative Commons

Chiu-Ying Hsiao,

Heng‐Chih Pan, Vin‐Cent Wu

et al.

Frontiers in Medicine, Journal Year: 2023, Volume and Issue: 10

Published: Sept. 19, 2023

Background COVID-19 and influenza can both lead to acute kidney injury (AKI) as a common complication. However, no meta-analysis has been conducted directly compare the incidence of AKI between hospitalized patients with influenza. The objective our study aims investigate outcomes among these two groups. Materials methods A systematic search PubMed, Embase, Cochrane databases was from December 2019 August 2023 identify studies examining clinical primary outcome interest AKI, while secondary included in-hospital mortality, recovery hospital ICU stay duration. quality evidence evaluated using GRADE methods. Results Twelve retrospective cohort studies, involving 17,618 influenza, were analyzed. showed higher (29.37% vs. 20.98%, OR: 1.67, 95% CI 1.56–1.80, p < 0.01, I 2 = 92.42%), mortality (30.95% 5.51%, 8.16, 6.17–10.80, 84.92%) compared AKI. Recovery lower in (57.02% vs., 80.23%, 0.33, 0.27–0.40, 85.17%). also had longer (SMD: 0.69, 0.65–0.72, 98.94%) 0.61, 0.50–0.73, 94.80%) than patients. In study, high (NOS score 7–9), low certainty for moderate form by assessment. Conclusion risk developing experiencing enduring prolonged hospital/ICU stays comparison Additionally, likelihood

Language: Английский

COVID-19 Infection in Chronic Kidney Disease Patients in Bulgaria: Risk Factors for Death and Acute Kidney Injury DOI Open Access
Rumen Filev, Lionel Rostaing,

Mila Lyubomirova

et al.

Journal of Personalized Medicine, Journal Year: 2022, Volume and Issue: 12(10), P. 1676 - 1676

Published: Oct. 9, 2022

Regarding COVID-19 infection, Bulgaria has one of the lowest rates vaccination in Europe, and its COVID-19-related mortality rate been highest European Union. Chronic kidney disease (CKD)-COVID-19 patients are at higher risk developing acute injury (AKI) death after hospital admission. This single-center prospective cohort study from included 120 in-patient subjects whom 70 had CKD 50 normal renal function. Diabetes mellitus, hypertension, obesity, cardiovascular were statistically more prevalent group as compared to non-CKD group. At admission, D-dimer, creatinine, urea levels significantly group, whereas estimated glomerular-filtration was lower patients. During hospitalization, 23 (19.1%) died, which 19 (p-value = 0.0096); addition, 38 developed AKI (31.6%), 31 0.0006). Using binary logistic regression, being male, having experienced AKI, not treated with remdesivir independent factors for COVID-19-induced mortality. symptoms than 6 days before baseline, received therapy predictive

Language: Английский

Citations

6

Organoids to Remodel SARS-CoV-2 Research: Updates, Limitations and Perspectives DOI Creative Commons

Yucheng An,

Yanjie He, Nan Ge

et al.

Aging and Disease, Journal Year: 2023, Volume and Issue: 14(5), P. 1677 - 1677

Published: Jan. 1, 2023

The novel COVID-19 pneumonia caused by the SARS-CoV-2 virus poses a significant threat to human health. Scientists have made efforts control this virus, consequently leading development of research methods. Traditional animal and 2D cell line models might not be suitable for large-scale applications in owing their limitations. As an emerging modelling method, organoids been applied study various diseases. Their advantages include ability closely mirror physiology, ease cultivation, low cost, high reliability; thus, they are considered choice further on SARS-CoV-2. During course studies, was shown infect variety organoid models, exhibiting changes similar those observed humans. This review summarises used research, revealing molecular mechanisms viral infection exploring drug screening tests vaccine that relied hence illustrating role remodelling research.

Language: Английский

Citations

2

Lesão renal aguda e Covid 19: perfil clínico-epidemiológico de pacientes em UTI em um hospital público do Distrito Federal DOI Open Access

Andréia Morais Teixeira,

Ana Claudia Rodrigues Da Silva,

Cleuma Ferreira de Almeida

et al.

Brazilian Journal of Development, Journal Year: 2023, Volume and Issue: 9(05), P. 17154 - 17166

Published: May 19, 2023

A disseminação do vírus SARS-CoV-2 que atingiu proporções mundiais, afetando mais de 100 países forma devastadora. Lesão Renal Aguda (LRA) é comum em pacientes graves internados UTI, e a evolução para Terapia Substitutiva (TRS) considerada fator prognóstico negativo relação à sobrevida. O presente estudo tem como objetivo geral identificar o perfil clínico dos admitidos na UTI um Hospital Público Distrito Federal com diagnóstico COVID -19 evoluíram LRA necessidade TRS. Trata-se uma pesquisa descritiva, exploratória, retrospectiva, abordagem quantitativa. obtenção dados foi feita através da análise prontuários físicos digitais documentados formulário elaborado pelo pesquisador.

Citations

1

Urine Parameters in Patients with COVID-19 Infection DOI Creative Commons
Maria Morello,

Dominga Amoroso,

Felicia Losacco

et al.

Life, Journal Year: 2023, Volume and Issue: 13(8), P. 1640 - 1640

Published: July 28, 2023

A urine test permits the measure of several urinary markers. This is a non-invasive method for early monitoring potential kidney damage. In COVID-19 patients, alterations markers were observed. review aims to evaluate utility urinalysis in predicting severity COVID-19. total 68 articles obtained from PubMed studies reported that (i) disease was related haematuria and proteinuria (ii) typical sediment noticed COVID-19-associated AKI patients. emphasizes microscopic examination support clinicians diagnosing severity.

Language: Английский

Citations

1

Acute kidney injury in patients with COVID-19 compared to those with influenza: a systematic review and meta-analysis DOI Creative Commons

Chiu-Ying Hsiao,

Heng‐Chih Pan, Vin‐Cent Wu

et al.

Frontiers in Medicine, Journal Year: 2023, Volume and Issue: 10

Published: Sept. 19, 2023

Background COVID-19 and influenza can both lead to acute kidney injury (AKI) as a common complication. However, no meta-analysis has been conducted directly compare the incidence of AKI between hospitalized patients with influenza. The objective our study aims investigate outcomes among these two groups. Materials methods A systematic search PubMed, Embase, Cochrane databases was from December 2019 August 2023 identify studies examining clinical primary outcome interest AKI, while secondary included in-hospital mortality, recovery hospital ICU stay duration. quality evidence evaluated using GRADE methods. Results Twelve retrospective cohort studies, involving 17,618 influenza, were analyzed. showed higher (29.37% vs. 20.98%, OR: 1.67, 95% CI 1.56–1.80, p < 0.01, I 2 = 92.42%), mortality (30.95% 5.51%, 8.16, 6.17–10.80, 84.92%) compared AKI. Recovery lower in (57.02% vs., 80.23%, 0.33, 0.27–0.40, 85.17%). also had longer (SMD: 0.69, 0.65–0.72, 98.94%) 0.61, 0.50–0.73, 94.80%) than patients. In study, high (NOS score 7–9), low certainty for moderate form by assessment. Conclusion risk developing experiencing enduring prolonged hospital/ICU stays comparison Additionally, likelihood

Language: Английский

Citations

1