Physiological Correlates of Hypnotizability: Neural Mechanisms of Hypnosis and Prognostic Role in Medicine DOI Open Access
Eleonora Malloggi, Enrica L. Santarcangelo

Published: Oct. 20, 2023

Studies in the field of experimental hypnosis highlighted role hypnotizability physiological variability general population. It is associated, fact, with a few differences which are observable ordinary state consciousness and absence suggestions. The aim present scoping review summarizing them, indicate their relevance to neural mechanisms prognosis treatment medical conditions. Individuals high, medium low scores display different cerebral functional – i.e., equivalence between imagery perception/action, excitability motor cortex, interoceptive accuracy - possibly related brain structural characteristics -, control blood supply at peripheral level, likely due availability endothelial nitric oxide. These reviewed support idea participation hypnotic behaviour prognostic therapeutic usefulness

Language: Английский

Dysregulation of Porphyromonas gingivalis Agmatine Deiminase Expression in Alzheimer’s Disease DOI

Asma Hamdi,

Sana Baroudi,

Alya Gharbi

et al.

Current Alzheimer Research, Journal Year: 2024, Volume and Issue: 21(4), P. 232 - 241

Published: April 1, 2024

Background: Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder, with a significant burden on global health. AD characterized by progressive cognitive decline and memory loss. Emerging research suggests potential link between periodontitis, specifically presence of oral bacteria such as Porphyromonas gingivalis (P. gingivalis), progression. P. produces an enzyme, Agmatine deiminase (AgD), which converts agmatine to N-carbamoyl putrescine (NCP), serving precursor essential polyamines. Recent studies have confirmed correlation disruptions in polyamine metabolism impairment. Objective: This study aims investigate dysregulation (PgAgD) context AD. Methods: Saliva samples were collected from total 54 individuals, including 27 patients healthy controls. The expression PgAgD gene was analyzed using quantitative Real-- Time PCR. Results: results showed decrease saliva compared downregulation found advanced stages periodontitis. Additionally, observed 30-item Mini-Mental State Examination (MMSE) score. Conclusion: These findings suggest that measuring could be noninvasive tool for monitoring progression aid early diagnosis Further needed validate our explore underlying mechanisms linking expression, pathophysiology.

Language: Английский

Citations

0

Salivary Antimicrobial Peptide in Patients With Dementia Before and After Clinical Oral Rehabilitation Programme: A Randomised Controlled Trial DOI
Ming‐An Chen, Yuan‐Han Yang, Ching‐Kuan Liu

et al.

Journal of Oral Rehabilitation, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 6, 2024

ABSTRACT Background Emerging evidence suggests a link between salivary metabolite changes and neurodegenerative dementia, with antimicrobial peptides (AMPs) implicated in its pathogenesis. Objective We investigated the effects of clinical oral rehabilitation programme tailored for dementia patients on flow rate, AMP levels health‐related quality life (OHRQoL). Methods Eligible were randomly assigned to either experimental group (EG; n = 28) or control (CG; 27). Both groups received leaflet health. In addition, EG an care intervention that included individual lessons muscle exercises self‐care practices. Saliva samples OHRQoL data collected at baseline follow‐up visits. Generalised estimating equation models used analyse over time. Results At 3‐month follow‐up, showed significantly lower histatin 5 (HTN‐5) ( β −0.08; effect size [ES] 0.72) than CG. 6 months, exhibited improved rate 0.89; ES 0.89) 6.99; 1.31) compared Changes 4.03), HTN‐5 level −0.78) beta‐defensin 2 (BD‐2) −0.91) 3 months predicted (all p < 0.05). Conclusions Our reduced HTN‐5, increased enhanced patients. Furthermore, BD‐2 associated improvements patients' OHRQoL.

Language: Английский

Citations

0

Oral Biofilm and Its Connection to Alzheimer’s Disease DOI Open Access
Gregori M Kurtzman, Robert Horowitz, Richard J. Johnson

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Dementia and Alzheimer's disease are common occurrences in the population, affecting many patients. Recent research studies have found a link between oral biofilm initiation of these conditions or worsening their presentation. Periodontal associated with its bacteria often not considered by medical community when treating Coordination therapy dentist can improve patient's health. Decreasing allows physician to provide coordinated total healthcare. Emphasis education patient on importance maintaining good homecare routine dental recall prophylaxis appointments systemic health limit progression mental conditions. This article discusses connection health, specifically disease, how those through

Language: Английский

Citations

0

Physiological Correlates of Hypnotizability: Neural Mechanisms of Hypnosis and Prognostic Role in Medicine DOI Open Access
Eleonora Malloggi, Enrica L. Santarcangelo

Published: Sept. 28, 2023

Studies in the field of experimental hypnosis highlighted role hypnotizability physiological variability general population. It is associated, fact, with a few differences which are observable ordinary state consciousness and absence suggestions. The aim present scoping review summarizing them, indicate their relevance to neural mechanisms prognosis treatment medical conditions. Individuals high, medium low scores display different cerebral functional – i.e., equivalence between imagery perception/action , excitability motor cortex, interoceptive accuracy - possibly related brain structural characteristics control blood supply at peripheral level, likely due availability endothelial nitric oxide. These reviewed support idea participation hypnotic behaviour prognostic therapeutic usefulness

Language: Английский

Citations

1

Physiological Correlates of Hypnotizability: Neural Mechanisms of Hypnosis and Prognostic Role in Medicine DOI Open Access
Eleonora Malloggi, Enrica L. Santarcangelo

Published: Oct. 20, 2023

Studies in the field of experimental hypnosis highlighted role hypnotizability physiological variability general population. It is associated, fact, with a few differences which are observable ordinary state consciousness and absence suggestions. The aim present scoping review summarizing them, indicate their relevance to neural mechanisms prognosis treatment medical conditions. Individuals high, medium low scores display different cerebral functional – i.e., equivalence between imagery perception/action, excitability motor cortex, interoceptive accuracy - possibly related brain structural characteristics -, control blood supply at peripheral level, likely due availability endothelial nitric oxide. These reviewed support idea participation hypnotic behaviour prognostic therapeutic usefulness

Language: Английский

Citations

1