Commentary: Bibliometric and visualized analysis of 2011–2020 publications on physical activity therapy for diabetes DOI Creative Commons
Yutian Chen,

Baitian Fu,

Jianqiao Fang

et al.

Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11

Published: Dec. 24, 2024

section, overlaps with the results section. In discussion, what needs to be conveyed readers is that bibliometric studies are conducted examine number of publications on a research topic, analyze current state research, and identify future potential growth patterns (7). keywords citation burst,the "impaired glucose tolerance" had highest strength, author pointed out many have revealed lifestyle changes like physical activity or exercise efficacy can prevent development T2DM. Although impaired tolerance (IGT) primary preventive indicator for diabetes, relationship between therapy IGT has not been reported. Some indicated certain impact indicators(8,9),the suggested "Previous also higher intensities adequate may provide greater benefit diabetes", which lacked supporting references."The key issue came how much intensity duration was enough health? What were health response short-time high-intensity vs. long-time low-intensity? As high vigorous relatively risk cardiovascular events, balance overall ? " The lacks further explanation address these uncertainties, only elaborates American Diabetes Association ' s recommendations diabetes patients in following sections, insufficient fully all aspects question posed. For example , Bicong Gao et al. (10) raised issues discussion section their article "What we learn from inflammatory mechanism?" However, they addressed issues, supported answers relevant literature, linked them article's theme an in-depth study interaction mechanism periodontitis while others attempted investigate association other systemic diseases, such as disease obesity, through host mechanism. consensus statements (11,12) established participation regular PA improves blood control delay type 2 diabetes. A clinical (13) presented details therapies used long-term studies, describing parameters prescriptions applied practice. These described terms frequency, intensity, duration, mode, rate progression therapeutic prescriptions.In conclusion, should simply rely obtained software Citespace Vosviewer, make simple record without analyzing significance results. there some doubts regarding description co-occurrence maps this article, it undeniable objectively highlights latest frontiers More attention paid future, treatment solely dependent medication, but involve prevention exercise, alleviate range diabetic complications.

Language: Английский

The gut microbiota regulates diabetic retinopathy in adult rats DOI Creative Commons

Jueyu Hou,

Zhongping Lv,

Yujiao Wang

et al.

Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 16

Published: Jan. 29, 2025

Introduction Diabetic retinopathy (DR) is the most common complication of diabetes. Neuronal apoptosis, activated microglia, and microvascular changes are early features DR. The gut microbiota critical for maturation activation microglia in brain, DR patients exhibit dysbiosis. However, effect on retinal under normal or diabetic conditions still unclear. Methods Type 2 diabetes (T2D) was established male adult Brown Norway (BN) rats, they were treated with gavage broad-spectrum antibiotic (ABX) suspension. Retinal fundus fluorescein angiography performed to observe dynamic growth process leakage blood vessels. Retro-orbital injection FITC-Dextran blood-retinal barriers. After treatment ABX lasting more than 6 months, 16S RNA sequencing stool samples determine microbiome mass spectrometry used analyze metabolome changes. IBA1, IB4, Brn3 staining rats’ wholemount sections vessels number ganglion cells. Results Long-term (6 months) T2D caused dysbiosis increased average taxa numbers. We showed that antibiotics (ABXs) can reduce BN rats without T2D. Interestingly, months a loss cells (RGCs) significant vascular reduced alleviated RGC damage these rats. Conclusion Our data suggests gavage-induced alleviate long-term Targeting may be future therapeutic strategy management.

Language: Английский

Citations

0
HIV and the gut microbiome: future research hotspots and trends DOI Creative Commons
Zhen Wu, Zailai Xie, Xinxin Cui

et al.

Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 7, 2025

Background The use of highly active antiretroviral therapy has transformed AIDS into a chronic infectious disease, but issues inflammation and immune system activation persist. Modulating the gut microbiome patients may improve this situation, yet specific association mechanisms between HIV remain unclear. This study aims to explore research hotspots trends microbiome, providing direction for future research. Methods We conducted search Web Science Core Collection database up April 30, 2024 retrieve articles related relationship microbiome. scientific achievements frontiers in field were analyzed using CiteSpace, VOSviewer, Bibliometrix statistical software. Results As 2024, total 379 met inclusion criteria. number publications peaked 2023, published after 2020 declined. country with highest was United States (184 articles), institution most University Colorado (USA) (21 articles). author Routy Jean-Pierre (Canada) (14 High-frequency keywords, aside from key terms, included “HIV,” “inflammation,” “immune activation,” “gut microbiota,” “translocation.” Keyword burst results indicated that short-chain fatty acids, T cells obesity might become focus Conclusion should prioritize examining role primary metabolite, reducing inflammation. Another emerging area interest could be investigation annual increase rates within field. Furthermore, understanding metabolic acids is essential. Additionally, multi-omics analysis holds potential.

Language: Английский

Citations

0
Gut microbiota regulates optic nerve fiber myelination DOI Creative Commons
Giulia Ronchi, Daniela Pellegrino, Marwa El Soury

et al.

Frontiers in Cell and Developmental Biology, Journal Year: 2025, Volume and Issue: 13

Published: Feb. 20, 2025

Recent evidence supports the hypothesis of an association between gut microbiota and pathogenesis retinal eye diseases, suggesting existence a gut-eye axis. However, no data are available on possible effect optic nerve fiber maturation myelin development. We investigated impact nerves collected from neonatal young adult germ-free (GF), gnotobiotic (stably colonized with 12 bacteria strains, OMM12) control (colonized complex microbiota, CGM) mice, by performing stereological morphoquantitative analyses transmission electron microscopy gene expression analysis quantitative real-time PCR. Young GF OMM12 axons smaller hypermyelinated compared to CGM ones, while such differences were detected in nerves. The transcription factors Olig1, Olig2, Sox10 (oligodendrocyte myelination positive regulators) downregulated mice respective neonates. Such developmental downregulation was not observed nerves, that absence prolongs stimulation myelination, possibly through mechanisms yet be identified. Altogether, these underscore pivotal role driving contributing our knowledge about both axis gut-brain axis, opening new horizons for further investigations will explore also pathologies, injuries regeneration associated nerve.

Language: Английский

Citations

0
Scientometric dynamics of scientific publications on gut microbiota and gluten: Overview, visualization, and mapping DOI
Fran Espinoza‐Carhuancho,

Alexander Taquia-Faustino,

Julia Medina

et al.

International journal of Nutrition Pharmacology Neurological Diseases, Journal Year: 2025, Volume and Issue: 15(1), P. 75 - 81

Published: Jan. 1, 2025

Background: The aim of the study was to analyze scientific production gut microbiota and gluten by overview, visualization, mapping. Methods: A descriptive with a scientometric approach carried out. search Scopus database performed on June 13, 2024, using specific formula covering period from January 2019 July 2024. Manuscripts were selected based their relevance field under study, 233 manuscripts identified. extracted data analyzed SciVal Bibliometrix. Results: total relevant published between 2024 journal Nutrients particularly prominent, contributing 28 articles demonstrating high productivity. Alessio Fasano recognized as most influential author in this field. Most papers ranked Q1 quartile, indicating quality. principles Bradford’s Lotka’s laws confirmed, some sources authors responsible for papers. Italy found be leading terms international collaborations. These findings offer valuable insights into output field, highlighting key trends identifying contributors. Conclusion: Trends highlighted, including , productivity Fasano, collaboration led Italy. provided insight distribution output.

Language: Английский

Citations

0
Mapping the evolution of anti-diabetic polysaccharides research: Trends, collaborations, and emerging frontiers DOI

Shengqi He,

Taotao Xue,

Ruoyu Geng

et al.

European Journal of Pharmacology, Journal Year: 2025, Volume and Issue: 997, P. 177479 - 177479

Published: March 6, 2025

Language: Английский

Citations

0
Scientometric Analysis of Research on Oral and Gut Microbiota and Periodontitis: Collaborative Networks, Emerging Patterns, Thematic Evolution DOI Open Access

Frank Mayta-Tovalino,

Fran Espinoza-Carhuancho,

M. Cruz

et al.

The Journal of Contemporary Dental Practice, Journal Year: 2025, Volume and Issue: 26(1), P. 86 - 92

Published: March 28, 2025

To perform a scientometric analysis of scientific literature related to microbiota and periodontitis. A search strategy was applied on 21 July 2024, identifying 1,069 papers from 408 different sources. However, nine articles could not be exported SciVal due incomplete metadata. The documents, including 722 articles, 282 reviews, 44 book chapters, among others, showed an annual growth rate 7.53%. Bibliometrix were used for data extraction analysis. total sources, published between 2019 identified. most frequent terms in the research "periodontitis", "oral microbiome", "microbiome", "periodontal disease", "dysbiosis". According Lotka's Law, authors field contributed small number papers. cited journals this "Frontiers Cellular Infection Microbiology", "Journal Oral "Periodontology 2000". Analysis thematic evolution shows increasing intersection topics recent research, reflecting multifaceted nature periodontitis its interaction with variety other health factors. Research is multifaceted, interacts factors, growing research. This study presents detailed review gut periodontitis, notes current developments, gives hints regarding still emerging themes. Its findings may serve continue future guidelines or understand relationship How cite article: Mayta-Tovalino F, Espinoza-Carhuancho Huaman-De la Cruz M, et al. Scientometric Gut Microbiota Periodontitis: Collaborative Networks, Emerging Patterns, Thematic Evolution. J Contemp Dent Pract 2025;26(1):86-92.

Language: Английский

Citations

0
Multi-omics Mendelian Randomization Reveals Immunometabolic Signatures of the Gut Microbiota in Optic Neuritis and the Potential Therapeutic Role of Vitamin B6 DOI Creative Commons

Jingzhi Wang,

Xuehao Cui

Molecular Neurobiology, Journal Year: 2025, Volume and Issue: unknown

Published: April 11, 2025

Optic neuritis (ON) is an inflammatory condition often linked to autoimmune disorders like multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). Despite its low incidence, ON can lead severe, irreversible visual impairment. Emerging evidence suggests the gut microbiota (GM) may influence through complex immune metabolic pathways, yet mechanisms remain underexplored. This study employed a multi-omics Mendelian randomization (MR) approach assess causal relationships between GM taxa ON. We analyzed data from extensive genetic profiling, examining effect 473 taxa, 731 cells/traits, 1400 metabolites, vitamin B6, Our methodology involved two-sample MR analysis establish causality mediation explore potential therapeutic strategies. identified 27 with direct relationship risk. Further highlighted three particularly strong associations. Mediation revealed specific pathways which these exert their effects, including notable interactions B6 metabolism, appeared mediate some of relationships. found that could be method by acting on in advances our understanding etiology highlights as target for The significant role new avenues prevention treatment, emphasizing need further research into diet-based interventions.

Language: Английский

Citations

0
Recent applications and prospects of omega-3 fatty acids: a bibliometric study and visualization analysis in 2014-2023 DOI

Zhaoxiang Wang,

Yiqian Yang,

Fengyan Tang

et al.

Prostaglandins Leukotrienes and Essential Fatty Acids, Journal Year: 2024, Volume and Issue: 201, P. 102615 - 102615

Published: Feb. 1, 2024

Language: Английский

Citations

2
Endophthalmitis: a bibliometric study and visualization analysis from 1993 to 2023 DOI Creative Commons
Xiangyu Fu,

Wenyu Du,

Ling Huang

et al.

Frontiers in Cellular and Infection Microbiology, Journal Year: 2024, Volume and Issue: 14

Published: July 16, 2024

This study is designed to generalize and depict the research hotspots of endophthalmitis through bibliometric methods software analyze evolutive tendency work on this severe disease over past 30 years. employed a rigorous approach. We identified all endophthalmitis-related literature by conducting comprehensive search Science Citation Index Expanded database under Web Core Collection. The data was then analyzed visualized using CiteSpace VOSviewer, two widely recognized tools in field bibliometrics. used country distributions, dual map overlay journals, keyword bursts, co-cited references. VOSviewer describe authors authors, keywords co-occurrence network. robust methodology ensures reliability validity study's findings. A total 2960 publications, including 2695 articles 265 reviews, were included study. There has been no shortage publications since 1993, with an apparent upward trend during recent Possible correlations COVID-19 pandemic are also analyzed. These studies finished 11,048 from 75 countries worldwide, United States lead. In network, except for term, cataract surgery becomes highest frequency. Different categories endophthalmitis, postoperative, post-injection, post-traumatic, endogenous antibacterial anti-inflammatory therapies infectious discussed categories. From perspective timeline, postoperative post-injection dominant forms before after year 2000, respectively. Co-citation analyses reveal that Endophthalmitis Vitrectomy Study (EVS) conducted 1995 provides pivotal guidance later research. Diverse pathogenic bacteria (e.g., Coagulase-negative Staphylococci, Propionibacterium acnes, Viridians Streptococci, Bacillus cereus) or fungi Candida, Aspergillus, Fusarium) contribute varying treatment principles clinical prognosis, which should be taken seriously. addition, intravitreal intracameral antibiotics mainstay treating preventing Our analysis overview dynamic evolution structural relationships endophthalmitis. displayed developmental directions have reference values future investigation.

Language: Английский

Citations

2
Gut microbiota and eye diseases: A review DOI Creative Commons

Yue Zhao,

Peijin Qiu,

Ting Shen

et al.

Medicine, Journal Year: 2024, Volume and Issue: 103(39), P. e39866 - e39866

Published: Sept. 27, 2024

Recent studies reveal that alterations in gut microbiota play a significant role the progression of various diseases, including those affecting eyes. The association between and eye health is an emerging focus research. This review seeks to summarize connection microbiome specific conditions, such as ocular surface funduscopic disorders immune-mediated diseases. Gut may influence these conditions by regulating immune system or altering metabolites, thereby contributing disease development. Strategies like probiotics, antibiotics, dietary modifications, fecal transplants show promise addressing issues. examines how be linked pathogenesis providing fresh therapeutic perspectives for ophthalmology.

Language: Английский

Citations

2