Hebamme, Journal Year: 2025, Volume and Issue: 38(01), P. 25 - 33
Published: Feb. 1, 2025
Vestnik ohrany materinstva i mladenčestva., Journal Year: 2025, Volume and Issue: 1(3), P. 42 - 52
Published: Jan. 14, 2025
Background . Gestational Diabetes Mellitus (GDM) is a common disorder that getting special attention recently due to the unwanted outcomes it leaves on health of both women and their offspring. New approaches are being applied in order develop strategies prevent GDM its consequences metabolic physiological state. One factors have been thought be involved pathology behind this microbiome. Objective: determine current evidence regarding association maternal microbiota composition with gestational diabetes mellitus discuss possibility management using Material methods. An extensive literature review was conducted MEDLINE database (PubMed) keywords filter: randomized controlled trial, meta-analysis, systematic review. Research results. This summarizes main data influence diversity occurrence development GDM. Although there were some inconsistencies among results, pattern significant changes gut, oral, vaginal microbiome observed. It found gut significantly associated Specifically, abundance certain bacteria anincreased risk GDM, while other may beassociated improved insulin sensitivity. In addition, alterations gutmicrobiota affect blood glucose control through variety mechanisms, including production short-chain fatty acids, activation inflammatory pathways, metabolism B vitamin group. Conclusion. We concluded clear existing correlation between microbial communities, where specific patterns observed oral tracts pregnant women. These findings, although having limitations, promising encouraging target human novel therapeutic plans treat or next generation probiotics parabiotics. Future studies should assess efficacy such
Language: Английский
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Hebamme, Journal Year: 2025, Volume and Issue: 38(01), P. 25 - 33
Published: Feb. 1, 2025
Citations
0