Gut Microbiota Dysbiosis: Pathogenesis, Diseases, Prevention, and Therapy DOI Creative Commons
Vicky Yao,

Nairui Fan,

Shuxia Ma

et al.

MedComm, Journal Year: 2025, Volume and Issue: 6(5)

Published: April 18, 2025

ABSTRACT Dysbiosis refers to the disruption of gut microbiota balance and is pathological basis various diseases. The main pathogenic mechanisms include impaired intestinal mucosal barrier function, inflammation activation, immune dysregulation, metabolic abnormalities. These involve dysfunctions in gut–brain axis, gut–liver others cause broader effects. Although association between diseases caused by dysbiosis has been extensively studied, many questions remain regarding specific treatment strategies. This review begins examining causes summarizes potential representative imbalance. It integrates clinical evidence explore preventive therapeutic strategies targeting emphasizing importance understanding dysbiosis. Finally, we summarized development artificial intelligence (AI) research suggested that it will play a critical role future studies on combining multiomics technologies AI further uncover complex drive personalized

Language: Английский

Effects of the oral probiotic Familact on dyspnea management in COPD patients: A randomized controlled trial DOI

Mehdi Aghamohammadi,

Samad Ghodrati, Nooshin Jalili

et al.

Heart & Lung, Journal Year: 2025, Volume and Issue: 71, P. 63 - 68

Published: Feb. 27, 2025

Language: Английский

Citations

0
Gut Microbiota Dysbiosis: Pathogenesis, Diseases, Prevention, and Therapy DOI Creative Commons
Vicky Yao,

Nairui Fan,

Shuxia Ma

et al.

MedComm, Journal Year: 2025, Volume and Issue: 6(5)

Published: April 18, 2025

ABSTRACT Dysbiosis refers to the disruption of gut microbiota balance and is pathological basis various diseases. The main pathogenic mechanisms include impaired intestinal mucosal barrier function, inflammation activation, immune dysregulation, metabolic abnormalities. These involve dysfunctions in gut–brain axis, gut–liver others cause broader effects. Although association between diseases caused by dysbiosis has been extensively studied, many questions remain regarding specific treatment strategies. This review begins examining causes summarizes potential representative imbalance. It integrates clinical evidence explore preventive therapeutic strategies targeting emphasizing importance understanding dysbiosis. Finally, we summarized development artificial intelligence (AI) research suggested that it will play a critical role future studies on combining multiomics technologies AI further uncover complex drive personalized

Language: Английский

Citations

0