Increased bacterial load of Filifactor alocis in deep periodontal pockets discriminate between periodontitis stage 3 and 4 DOI Creative Commons

Reem H. Faisal,

Alaa Omran Ali

Frontiers in Oral Health, Journal Year: 2025, Volume and Issue: 6

Published: March 27, 2025

Introduction Increasing evidence supports the association of Filifactor alocis with periodontitis; therefore, this work was conducted to assess prevalence and proportion F. in subgingival biofilm samples from patients periodontitis stage 3 4, its potential differentiate between these stages. Methods This cross-sectional study included 50 whom were collected using paper points. followed by recording clinical periodontal parameters including plaque index, bleeding on probing, probing pocket depth (PPD), attachment loss (CAL). The total loads bacteria determined via quantitative PCR. Results All diagnosed 3/4 grade B/C, a 727 pockets, which pooled ( n = 114) for microbiological analysis. Qualitative analyses indicated that bacterial load highest 4 C cases, also increased increasing PPD severity CAL. An ROC analysis both concentration could significantly discriminate periodontitis. regression model suggested one-unit increase PPD, CAL explain 23.9% 14.9% concentration, respectively. Conclusion results demonstrate is severe mainly at sites deep pockets greater loss. Additionally, bacterium possesses diagnostic cases different severities.

Language: Английский

Increased bacterial load of Filifactor alocis in deep periodontal pockets discriminate between periodontitis stage 3 and 4 DOI Creative Commons

Reem H. Faisal,

Alaa Omran Ali

Frontiers in Oral Health, Journal Year: 2025, Volume and Issue: 6

Published: March 27, 2025

Introduction Increasing evidence supports the association of Filifactor alocis with periodontitis; therefore, this work was conducted to assess prevalence and proportion F. in subgingival biofilm samples from patients periodontitis stage 3 4, its potential differentiate between these stages. Methods This cross-sectional study included 50 whom were collected using paper points. followed by recording clinical periodontal parameters including plaque index, bleeding on probing, probing pocket depth (PPD), attachment loss (CAL). The total loads bacteria determined via quantitative PCR. Results All diagnosed 3/4 grade B/C, a 727 pockets, which pooled ( n = 114) for microbiological analysis. Qualitative analyses indicated that bacterial load highest 4 C cases, also increased increasing PPD severity CAL. An ROC analysis both concentration could significantly discriminate periodontitis. regression model suggested one-unit increase PPD, CAL explain 23.9% 14.9% concentration, respectively. Conclusion results demonstrate is severe mainly at sites deep pockets greater loss. Additionally, bacterium possesses diagnostic cases different severities.

Language: Английский

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