Impact of hypertensive heart disease, risk factors, and age-period-cohort models across 204 nations and regions from 1990 to 2019: a global perspective from the 2019 global burden of disease study

Frontiers in Cardiovascular Medicine, Journal Year: 2024, Volume and Issue: 11

Published: July 18, 2024

Background Hypertensive heart disease (HHD) is a major global public health issue resulting from hypertension-induced end-organ damage. The aim of this study was to examine the impact, risk factors, and age-period-cohort (APC) model HHD 1990 2019. Methods Data 2019 Global Burden Disease were used assess age-adjusted prevalence, disability-adjusted life years (DALYs), mortality rates, contributions factors with 95% uncertainty intervals (UIs). APC models analyze age, period, cohort trends for HHD. Results In 2019, 18.6 million prevalent cases led 1.16 fatalities 21.51 DALYs. Age-adjusted rates 233.8 (95%UI = 170.5–312.9) per 100,000 individuals 15.2 (11.2–16.7) mortality, 268.2 (204.6–298.1) Regionally, Cook Islands (703.1), Jordan (561.6), Kuwait (514.9) had highest age-standardized incidence in There significant increases prevalence Andean Latin America (16.7%), western sub-Saharan Africa (5.6%), eastern (4.6%). Mortality rate varied widely among countries. Risk like elevated systolic blood pressure high body mass index influenced DALY especially females. revealed an association between decreasing over time improved survival later birth cohort. Conclusions Despite reduction remains issue, particularly nations low sociodemographic indices. To alleviate impact HHD, prevention efforts should concentrate on management hypertension, weight loss, lifestyle improvement.

Language: Английский

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Plant Antioxidants: Therapeutic Potential in Cardiovascular Diseases

Compounds, Journal Year: 2024, Volume and Issue: 4(3), P. 479 - 502

Published: Aug. 12, 2024

Cardiovascular diseases (CVDs) are a global health problem. The mortality associated with them is one of the highest. Essentially, CVDs occur when heart or blood vessels damaged. Oxidative stress an imbalance between production reactive oxygen species (free radicals) and antioxidant defenses. Increased can cause cardiac vascular injuries, leading to CVDs. Antioxidant therapy has been shown have beneficial effects on Plants rich source bioactive antioxidants our planet. Several classes these compounds identified. Among them, carotenoids phenolic most potent antioxidants. This review summarizes role some (a/β-carotene, lycopene lutein), polyphenols such as acids (caffeic, p-coumaric, ferulic chlorogenic acids), flavonoids (quercetin, kaempferol epigallocatechin gallate), hydroxytyrosol in mitigating by studying their biological mechanisms. Through detailed analysis, we aim provide deeper understanding how natural be integrated into cardiovascular strategies help reduce overall burden CVD.

Language: Английский

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Lipoprotein(a) and heart failure: a systematic review

Heart Failure Reviews, Journal Year: 2023, Volume and Issue: 28(6), P. 1307 - 1314

Published: July 19, 2023

Language: Английский

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Towards Optimal Cardiovascular Health: A Comprehensive Review of Preventive Strategies

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: May 22, 2024

Heart disease remains a prominent global health concern, with cardiovascular (CVD) standing as leading cause of death worldwide. Preventing heart not only decreases the risk premature but also mitigates complications like attacks, strokes, and arrhythmias, thereby enhancing overall quality life. The economic burden treatment highlights importance implementing preventive measures, such lifestyle changes early interventions, which can alleviate healthcare costs. These strategies, targeting factors hypertension (HTN), diabetes mellitus (DM), dyslipidemia, obesity, prevent reduce other issues. Herein, this review covers various including dietary exercise, controlling HTN, DM, cholesterol, weight, smoking cessation, pharmacological interventions. By critically analyzing guidelines leveraging robust data alongside variations in recommendations, aims to elucidate effective primary prevention strategies for CVD.

Language: Английский

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Global prevalence and disability-adjusted life years of hypertensive heart disease: A trend analysis from the Global Burden of Disease Study 2019

Journal of Global Health, Journal Year: 2024, Volume and Issue: 14

Published: Aug. 30, 2024

As hypertensive heart disease (HHD) presents a significant public health challenge globally, we analysed its global, regional, and national burdens trends from 1990 to 2019.

Language: Английский

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