Importance of non‐cardiovascular comorbidities in atrial fibrillation and heart failure with preserved ejection fraction DOI Creative Commons
Yasuhiro Hamatani, Moritake Iguchi,

Takao Kato

et al.

ESC Heart Failure, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 21, 2024

Abstract Aims Atrial fibrillation (AF) and heart failure (HF) with preserved ejection fraction (HFpEF) are interlinked frequently coexisting conditions. To date, patients AF HFpEF have limited evidence guiding their management. This study aimed to investigate the predictors of adverse outcomes among HFpEF. Methods The Fushimi Registry is a community‐based prospective survey in Fushimi‐ku, Kyoto, Japan. From registry, we explored for composite cardiac death or HF hospitalization (defined as having prior New York Heart Association class ≥2 association disease left ventricular ≥50%). Besides, investigated whether scoring using identified by could stratify registered another independent Kyoto Congestive Failure Registry. Results Of 755 [mean age: 77.5 ± 9.9 years; female: 391 (52%); paroxysmal AF: 258 (34%); mean CHA 2 DS ‐VASc score: 4.5 1.5], occurred 246 (33%) during median follow‐up period 4.4 years Using multivariate Cox regression analysis, age ≥75 [hazard ratio (HR): 1.72, 95% confidence interval (CI): 1.26–2.36] non‐cardiovascular comorbidities such anaemia (HR: 1.83, CI: 1.37–2.46), chronic kidney 1.69, 1.27–2.26), diabetes mellitus 1.55, 1.15–2.09) obstructive pulmonary 1.87, 1.08–3.22) were outcomes. Meanwhile, cardiovascular including coronary artery disease, valvular cardiomyopathy not significantly associated These results also case when analysed who registry ( N = 878). score assigning 1 point each five (age, anaemia, disease; ranging 0–5 points) stratified incidence well those (both log‐rank; P < 0.001). Conclusions Non‐cardiovascular addition advanced Our suggests importance focusing on these individualized risk stratification optimal management

Language: Английский

The Left Atrium in Heart Failure with Preserved Ejection Fraction DOI Creative Commons

Romanos Haykal,

Ahmad Kassar, Nadia Chamoun

et al.

Heart Rhythm O2, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Importance of non‐cardiovascular comorbidities in atrial fibrillation and heart failure with preserved ejection fraction DOI Creative Commons
Yasuhiro Hamatani, Moritake Iguchi,

Takao Kato

et al.

ESC Heart Failure, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 21, 2024

Abstract Aims Atrial fibrillation (AF) and heart failure (HF) with preserved ejection fraction (HFpEF) are interlinked frequently coexisting conditions. To date, patients AF HFpEF have limited evidence guiding their management. This study aimed to investigate the predictors of adverse outcomes among HFpEF. Methods The Fushimi Registry is a community‐based prospective survey in Fushimi‐ku, Kyoto, Japan. From registry, we explored for composite cardiac death or HF hospitalization (defined as having prior New York Heart Association class ≥2 association disease left ventricular ≥50%). Besides, investigated whether scoring using identified by could stratify registered another independent Kyoto Congestive Failure Registry. Results Of 755 [mean age: 77.5 ± 9.9 years; female: 391 (52%); paroxysmal AF: 258 (34%); mean CHA 2 DS ‐VASc score: 4.5 1.5], occurred 246 (33%) during median follow‐up period 4.4 years Using multivariate Cox regression analysis, age ≥75 [hazard ratio (HR): 1.72, 95% confidence interval (CI): 1.26–2.36] non‐cardiovascular comorbidities such anaemia (HR: 1.83, CI: 1.37–2.46), chronic kidney 1.69, 1.27–2.26), diabetes mellitus 1.55, 1.15–2.09) obstructive pulmonary 1.87, 1.08–3.22) were outcomes. Meanwhile, cardiovascular including coronary artery disease, valvular cardiomyopathy not significantly associated These results also case when analysed who registry ( N = 878). score assigning 1 point each five (age, anaemia, disease; ranging 0–5 points) stratified incidence well those (both log‐rank; P < 0.001). Conclusions Non‐cardiovascular addition advanced Our suggests importance focusing on these individualized risk stratification optimal management

Language: Английский

Citations

1