Agrochemicals,
Journal Year:
2023,
Volume and Issue:
2(3), P. 367 - 408
Published: July 10, 2023
Use
of
glyphosate
and
glyphosate-based
herbicides
is
ubiquitous
in
US
agriculture
widespread
around
the
world.
Despite
marketing
efforts
to
contrary,
numerous
studies
demonstrate
toxicity
non-target
organisms
including
animals,
primarily
focusing
on
mortality,
carcinogenicity,
renal
toxicity,
reproductive,
neurological
biochemical
mechanisms
underlying
these
physiological
outcomes.
Glyphosate
also
impacts
animal
behavior,
both
model
systems
agricultural
environmentally
relevant
contexts.
In
this
review,
we
examine
effects
behaviors,
particularly
activity,
foraging
feeding,
anti-predator
reproductive
learning
memory,
social
behaviors.
can
be
detected
food
environment,
avoided
through
activity
feeding
strategies.
However,
exposure
reduces
depresses
increases
susceptibility
predation,
interferes
with
courtship,
mating,
fertility
maternal
decreases
memory
capabilities,
disrupts
Changes
behavior
as
a
result
are
important
because
their
sometimes
severe
individual
fitness,
well
ecosystem
health.
Implications
for
human
considered.
Desalination and Water Treatment,
Journal Year:
2024,
Volume and Issue:
317, P. 100271 - 100271
Published: Jan. 1, 2024
In
this
paper,
phosphorus
removal
experiments
were
conducted
on
the
by-product
salt
of
glyphosate
using
a
chemical
precipitation
process.
The
precipitates
after
characterized
microscopical
techniques,
including
scanning
electron
microscopy
(SEM),
X-ray
diffraction
(XRD),
Fourier-transform
infrared
spectroscopy
(FT-IR),
and
energy-dispersive
(EDS).
Investigated
efficiency
polyaluminum
chloride
(PAC)
coagulant
evaluated
influence
various
factors
such
as
dosage,
pH,
settling
time.
experimental
results
indicate
that
when
ratio
dosage
to
total
content
is
10:1,
with
an
initial
solution
pH
7
time
45
minutes,
in
can
be
reduced
from
242
mg/L
6.49
mg/L,
achieving
rate
97.32%.
composite
polyacrylamide
(PAM)
parameters
type
polyacrylamide,
selecting
cationic
molecular
weight
300,000,
1:6,
7.5,
25
minutes
reduce
1.94
99.20%.
Frontiers in Toxicology,
Journal Year:
2024,
Volume and Issue:
6
Published: Sept. 18, 2024
Glyphosate
is
a
chemical
compound
derived
from
glycine,
marketed
as
broad-spectrum
herbicide,
and
represents
one
of
the
most
widely
used
pesticides
in
world.
For
long
time,
it
was
assumed
that
glyphosate
harmless,
either
due
to
its
selective
enzymatic
acting
method
on
plants,
because
commercial
formulations
were
believed
contain
only
inert
chemicals.
spread
environment,
general
population
daily
exposed
via
different
routes,
including
consumption
both
plant,
non-plant
based
foods.
has
been
detected
high
amounts
workers’
urine,
but
likewise
bodily
fluids,
such
blood
maternal
milk,
also
60%–80%
population,
children.
Considering
massive
presence,
exposure
could
be
considered
health
risk
for
humans.
Indeed,
2015,
IARC
(International
Agency
Research
Cancer)
classified
derivatives
Group
2A,
probable
human
carcinogens.
In
2022,
nevertheless,
EFSA
(European
Food
Safety
Authority)
stated
available
data
did
not
provide
sufficient
evidence
prove
mutagenic/carcinogenic
effects
glyphosate.
Therefore,
European
Commission
(EC)
decided
renew
approval
another
10
years.
The
purpose
this
review
examine
scientific
literature,
focusing
potential
risks
arising
glyphosate,
metabolites
products
(e.g.,
Roundup
®
),
with
particular
regard
mutagenic
carcinogenic
endocrine
disrupter
(ED)
especially
reproductive
system.
Journal of Xenobiotics,
Journal Year:
2025,
Volume and Issue:
15(1), P. 23 - 23
Published: Feb. 2, 2025
Background:
Glyphosate
has
been
extensively
used
as
herbicide
since
the
early
1970s.
The
daily
exposure
limit
is
set
at
0.3
mg/kg
bw/d
in
Europe
and
1.75
USA.
Among
its
derivatives,
aminomethylphosphonic
acid
most
stable
abundant.
Understanding
their
biological
effects
then
requires
reliable
methods
for
quantification
samples.
Methods:
We
developed
validated
a
fast,
low-cost,
chromatographic
method
determining
glyphosate
concentrations.
validation
included
following
parameters:
specificity,
selectivity,
matrix
effect,
accuracy,
precision,
calibration
performance,
of
quantification,
recovery,
stability.
Sample
extraction
employed
an
anion
exchange
resin
with
elution
using
hydrochloric
50.0
mmol/L.
For
HPLC
analysis,
analytes
were
derivatized,
separated
on
C18
column
mobile
phase
phosphate
buffer
(0.20
mol/L,
pH
3.0)
acetonitrile
(85:15),
detected
240
nm.
Results:
demonstrated
high
reliability
reproducibility
across
various
matrices.
Its
performance
met
all
criteria,
confirming
suitability
quantifying
different
experimental
setups.
Conclusions:
This
can
offer
practical
resource
applications
research,
medical
diagnostics,
quality
control,
food
safety.
Journal of Occupational Medicine and Toxicology,
Journal Year:
2025,
Volume and Issue:
20(1)
Published: Feb. 25, 2025
Herbicides
are
a
group
of
substances
used
to
control
undesired
vegetation
in
both
agricultural
and
non-agricultural
settings.
They
recorded
as
the
most
consumed
class
among
other
pesticides,
reaching
nearly
two
million
tons
worldwide.
Despite
their
effectiveness
weed
control,
extensive
utilization
herbicides
has
raised
concerns
regarding
adverse
effects
on
human
health.
However,
comprehensive
reviews
addressing
herbicide-related
health
risks
remain
limited.
This
work
aims
compile
scientific
evidence
possible
underlying
mechanisms
emphasize
hazards
that
need
be
acknowledged,
well
explore
novel
strategies
for
minimizing
impact
Scientific
data
risks,
including
human-related
non-human
experimental
research,
were
retrieved
from
databases
such
PubMed,
Scopus,
Google
Scholar.
Pre-determined
eligibility
criteria
applied
select
final
studies.
A
narrative
summary
evidence-based
incidence
laboratory
experiments
is
presented
organize
highlight
key
findings.
indicates
life-threatening
nature
herbicide
exposure
humans,
ranging
acute
toxicity
development
chronic
diseases
at
any
stage
life.
Herbicidal
chemicals
can
harm
individuals
through
various
pathways,
especially
by
inducing
oxidative
stress
or
directly
disrupting
molecular
cellular
processes.
some
conflicting
findings,
effective
mitigation
urgently
needed
promote
safer
society
protect
well-being.
Environment International,
Journal Year:
2025,
Volume and Issue:
199, P. 109480 - 109480
Published: April 17, 2025
Glyphosate
is
the
most
widely
used
pesticide
worldwide.
Few
epidemiologic
studies
have
examined
potential
for
neurotoxicity
by
glyphosate
or
its
degradate,
Aminomethylphosphonic
Acid
(AMPA).
We
associations
of
maternal
urinary
and
AMPA
concentrations
with
child
cognitive,
social,
behavioural
functioning
in
participants
enrolled
Maternal-Infant
Research
on
Environmental
Chemicals
(MIREC)
study.
Maternal
were
measured
first
trimester
spot
urine
samples.
assessed
children's
cognition
(IQ)
at
3-4
years
age
(n
=
572)
using
Wechsler
Preschool
Primary
Scale
Intelligence-III.
Social
566)
840)
parent-report
versions
Responsiveness
Scale-2
Behavioral
Assessment
System
Children-2.
quantified
between
neurodevelopmental
outcomes
multivariable
linear
regression
models
effect
modification
sex,
folic
acid,
plasma
folate.
Median
(IQR)
0.31
(0.33)
μg/L
0.25
(0.25)
μg/L.
not
significantly
associated
social
functioning,
there
was
no
evidence
modification.
found
a
non-significant
inverse
trend
Performance
IQ
(B
-0.85;
95
%CI:
-1.71,0.01).
In
this
primarily
urban
cohort
Canadian
mother-child
pairs,
prenatal
exposure
neurodevelopment.
Further
evaluation
as
developmental
neurotoxicant
study
multiple
samples
per
participant
higher
levels
warranted.
