Clinical Characteristics, Metabolic Parameters, and Risk Factors for Suicide Attempts Vary with Untreated Major Depressive Disorder Duration DOI Open Access
Ping Tong,

Yang Hang Shi,

Liang Yu

et al.

Depression and Anxiety, Journal Year: 2023, Volume and Issue: 2023, P. 1 - 9

Published: Dec. 21, 2023

Suicidal attempts (SAs) are common in major depressive disorder (MDD). However, only few studies have so far assessed how risk factors for SAs patients with MDD might be related to the duration of untreated illness (DUI). We interviewed 1,718 drug-naive outpatients first-episode and divided them into groups that had not attempted suicide. DUI was used as an additional grouping criterion. The (20.14%; 346/1718) who a history were older longer DUI; lower educational level (middle school-educated only); more psychotic symptoms; higher scores on depression anxiety scales; BP, plasma BG, TC, LDL-C levels, but HDL-C concentrations. Anxiety symptoms, high education level, being unmarried SA DUIs <3 months; low BMI, group between 3 8 age, systolic blood pressure those > months. This study single-center cross-sectional survey, its limitations include lack outside validation. Patients without different clinical characteristics metabolic parameters, suicide vary across stages. general factor, suggesting clinicians should strengthen their assessment during diagnosis treatment.

Language: Английский

Metabolic and Endocrine Correlates of Subclinical Hypothyroidism in Young Adults with First-Episode and Drug-Naive Major Depressive Disorder DOI

ZhaoXuan Shang,

ChunQing Fang,

Xiaoe Lang

et al.

Journal of the Academy of Consultation-Liaison Psychiatry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

Citations

0
Clinical Patterns of Metabolic Syndrome in First-Hospitalized Major Depressive Disorder Patients: Comparison of Antidepressant-Exposed and Drug-Naïve Groups DOI Creative Commons
Si Wang, Lin Zhang, Yigao Wu

et al.

Neuropsychiatric Disease and Treatment, Journal Year: 2024, Volume and Issue: Volume 20, P. 2159 - 2168

Published: Nov. 1, 2024

Major depressive disorder (MDD) and metabolic syndrome (MetS) are both major health threats nowadays, the relationship between them is complex close. The purpose of this paper to compare differences in prevalence risk factors MetS first hospitalized patients with MDD without antidepressant exposure.

Language: Английский

Citations

0
Anxious Depression in Major Depressive Disorder: Key Influences and Prevalence in Chinese Hospitalized Patients DOI Creative Commons

Yali Zhu,

Wu Yin,

Jun Ma

et al.

Neuropsychiatric Disease and Treatment, Journal Year: 2024, Volume and Issue: Volume 20, P. 2267 - 2275

Published: Nov. 1, 2024

Anxious depression (AUD) is a common subtype of major depressive disorder (MDD) and has significant negative impact on disease progression patient prognosis. Our study aimed to determine the frequency AUD in Chinese patients with MDD during their first hospitalization identify factors that may influence emergence intensity these AUD.

Language: Английский

Citations

0
Incidence and Factors Associated with Hyperglycemia in Patients with First Hospitalization for Major Depression Disorder: A Large Cross-Sectional Sample DOI Creative Commons

Shuangyu Qi,

Xu Yang, Kuan Zeng

et al.

Neuropsychiatric Disease and Treatment, Journal Year: 2023, Volume and Issue: Volume 19, P. 1809 - 1818

Published: Aug. 1, 2023

Major depressive disorder (MDD) is a mood characterized by persistent spontaneous depression and has high rate of disability mortality. There complex relationship between MDD disorders glucose metabolism, our study aimed to investigate the prevalence risk factors for hyperglycemia in patients with who were hospitalized first times.A total 981 first-time inpatients recruited, socio-demographic information, anthropometric data, biochemical parameters collected each participant. The 17-item Hamilton Assessment Scale Depression (HAMD-17), 14-item Anxiety (HAMA-14), Positive Syndrome (PSS), Clinical General Impressions Inventory-Severity Illness (CGI-SI) scores used assess patients' clinical symptoms.The was 9.28% among time. Compared non-hyperglycemic subgroup, hyperglycemic subgroup found have more extensive significant demographic characteristics, higher levels metabolism-related parameters, severe psychological psycho-pathological symptoms. Age, thyroid stimulating hormone (TSH), triglycerides (TG) patients, while course disease protective factor.The findings suggest that not are variables predicting include age, TSH TG. above three good combined diagnostic ability hyperglycemia.

Language: Английский

Citations

1
Prevalence, correlates, and network analysis of depression and its associated quality of life among ophthalmology nurses during the COVID-19 pandemic DOI Creative Commons
Zihan Liu, Yue Li, Zirong Tian

et al.

Frontiers in Psychology, Journal Year: 2023, Volume and Issue: 14

Published: Aug. 24, 2023

Nurses in Ophthalmology Department (OD) had a high risk of infection during the novel coronavirus disease 2019 (COVID-19) pandemic. This study examined prevalence, correlates, and network structure depression, explored its association with quality life (QOL) Chinese OD nurses.Based on cross-sectional survey, demographic clinical data were collected. Depression was measured 9-item Self-reported Patient Health Questionnaire (PHQ-9), QOL using World Organization Quality Life Questionnaire-brief version (WHOQOL-BREF). Univariate analyses, multivariate logistic regression analyses performed.Altogether, 2,155 nurses included. The overall prevalence depression among 32.71% (95%CI: 30.73-34.70%). Multiple analysis revealed that having family or friends colleagues who infected (OR = 1.760, p 0.003) significantly associated higher depression. After controlling for covariates, reported lower (F(1, 2,155) 596.784, < 0.001) than those without Network 'Sad Mood', 'Energy Loss' 'Worthlessness' key central symptoms.Depression common COVID-19 Considering negative impact daily life, regular screening timely counselling service, psychiatric treatment should be provided nurses, especially family/friends colleagues. Central symptoms identified targeted

Language: Английский

Citations

1
Prevalence and factors associated with metabolic syndrome in patients with first hospitalization for major depression disorder：a large sample cross-sectional study DOI Creative Commons

Zhongyu Tang,

Lin Zhang, Xuebing Liu

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: May 9, 2023

Abstract Metabolic syndrome (MetS) is a common comorbidity of major depressive disorder (MDD) that has serious adverse effects on physical health. The purpose this study to investigate the prevalence and factors influencing MetS in patients hospitalized for their first episode MDD. included 981 who were admitted Data demographic clinical characteristics gathered, along with measurements metabolism-related parameters assessments psychological psychopathological symptoms. population was 9.68%. Patients both MDD found have more extensive significant characteristics, higher levels parameters, severe Risk diagnosis onset age MDD, HAMD scores, TSH levels. risk scores older age, being married, PSS TC, while LDL-C protective. Our results suggest not highly prevalent but certain may increase its likelihood severity.

Language: Английский

Citations

0
Association of major depression, schizophrenia and bipolar disorder with thyroid cancer: a bidirectional two-sample Mendelian randomized study DOI Creative Commons
Rongliang Qiu, Huihui Lin, Hongzhan Jiang

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Dec. 8, 2023

Abstract Background: Major depression disease (MDD), schizophrenia (SCZ), and bipolar disorder (BD) are common psychiatric disorders the relationship with thyroid cancer has been of great interest. This study aimed to investigate potential causal effects MDD, SCZ, BD, cancer. Method: We used publicly available summary statistics from large-scale genome-wide association studies select genetic variant loci associated major as instrumental variables (IVs), which were quality-controlled clustered, we three Mendelian randomization (MR) methods: inverse variance weighted (IVW), MR-Egger regression Weighted Median Estimator(WME) methods estimate a bidirectional between mental illness In addition, performed heterogeneity multivariate tests verify validity IVs. Result: two-sample MR analysis find positive MDD risk. The results IVW (OR = 3.956 95% CI= 1.177-13.299; P 0.026) WME method 5.563 0.998-31.008; 0.050) confirmed that may increase risk same conclusion. Additionally, our found correlation susceptibility SCZ 1.532 1.123-2.088; 0.007). based on median 1.599 1.014-2.521; 0.043) also supported Furthermore, did not BD reverse showed no significant causality (P>0.05), ruling out possibility causality. Conclusions: provides new evidence support be positively risk, while These have important implications for public health policy clinical practice. Future will help elucidate this association's biological mechanisms confounders.

Language: Английский

Citations

0
Clinical Characteristics, Metabolic Parameters, and Risk Factors for Suicide Attempts Vary with Untreated Major Depressive Disorder Duration DOI Open Access
Ping Tong,

Yang Hang Shi,

Liang Yu

et al.

Depression and Anxiety, Journal Year: 2023, Volume and Issue: 2023, P. 1 - 9

Published: Dec. 21, 2023

Suicidal attempts (SAs) are common in major depressive disorder (MDD). However, only few studies have so far assessed how risk factors for SAs patients with MDD might be related to the duration of untreated illness (DUI). We interviewed 1,718 drug-naive outpatients first-episode and divided them into groups that had not attempted suicide. DUI was used as an additional grouping criterion. The (20.14%; 346/1718) who a history were older longer DUI; lower educational level (middle school-educated only); more psychotic symptoms; higher scores on depression anxiety scales; BP, plasma BG, TC, LDL-C levels, but HDL-C concentrations. Anxiety symptoms, high education level, being unmarried SA DUIs <3 months; low BMI, group between 3 8 age, systolic blood pressure those > months. This study single-center cross-sectional survey, its limitations include lack outside validation. Patients without different clinical characteristics metabolic parameters, suicide vary across stages. general factor, suggesting clinicians should strengthen their assessment during diagnosis treatment.

Language: Английский

Citations

0