Association between weekend catch-up sleep and depression in US adults

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 4, 2025

Language: Английский

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Muscle quality index is correlated with insulin resistance and type 2 diabetes mellitus: a cross-sectional population-based study

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 6, 2025

Muscle quality index (MQI), an emerging health index, is calculated by dividing handgrip strength skeletal muscle mass. Current evidence on the correlation between MQI and type 2 diabetes mellitus (T2DM), insulin resistance (IR) limited. This work aims to study that correlation. involves a cross-sectional analysis data from National Health Nutrition Examination Survey (NHANES) during period 2011 2014. To explore MQI, IR T2DM, multivariate logistic regression, receiver operating characteristic (ROC) curve, subgroup analysis, restricted cubic spline regression were employed. A total of 2816 American adults enrolled in this study, among whom 1264 (44.9%) had IR, 300 (10.7%) T2DM. Logistic RCS analyses showed significant negative linearly prevalence (OR = 0.708, 95%=0.514, 0.976) T2DM 0.676, 95%CI 0.472, 0.969). Subgroup further revealed stronger individuals with obesity. ROC compared grip strength, (AUC 0.679 for 0.688 T2DM) can serve as more reliable identification factor provides decreased levels are correlated increased risk indicating potential utility marker identifying

Language: Английский

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Association between socioeconomic status and the triglyceride glucose index: a cross-sectional study based on NHANES 2007–2016

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 10, 2025

The triglyceride glucose index (TyG index) is a crucial marker for assessing the risk of chronic diseases, while socioeconomic status (SES), measured by poverty income ratio (PIR) and education level, reflects an individual's social standing. Past studies have linked SES to diabetes cardiovascular but research on its association with TyG limited. This study aimed explore between assess mediating role BMI. cross-sectional utilized data from National Health Nutrition Examination Survey 2007–2016 cycles relationship in adult USA. Multivariate logistic regression, stratified interaction analyses were conducted index. Additionally, parallel mediator analysis estimated mediated effect BMI Among 11,358 individuals studied, averaging 49 years age 48.3% males, fully adjusted models revealed negative associations PIR level index, showed positive correlation. Stratified indicated consistent findings across subgroups. Mediation that 14.4% 8.57% effects PIR/Education respectively. was negatively associated partially mediate These deepen comprehension

Language: Английский

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The joint effects of sleep duration and exercise habit on all-cause mortality among Chinese older adult: a national community-based cohort study

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: March 26, 2025

Abstract This study examines the combined effects of sleep duration and exercise habits on all-cause mortality in older Chinese adults using data from Longitudinal Healthy Longevity Survey (CLHLS). Methods Data were collected 7231 residents aged 60 above CLHLS. Participants categorized based their (short sleep: <6 hours, normal 6–8 long >8 hours) (physically active, physically inactive, inactive-to-active, active-to-inactive). The analysis was conducted over three follow-up periods (2011, 2014, 2018). Cox proportional hazards regression models used to assess associations between duration, habits, mortality. Results results showed that compared short sleepers, individuals with (6–8 had a slightly reduced risk death, although this reduction not statistically significant (HR = 0.97, 95% CI 0.87–1.08). In contrast, sleepers (>8 significantly higher 1.28, 1.16–1.43). Regarding regular or transitioning inactivity those who did 0.74, 0.66–0.83 HR 0.88, 0.80–0.97, respectively). Notably, impact among regardless gender. However, both men women experienced benefits exercise. Additionally, transitioned sedentary lifestyle physical activity during demonstrated lower rates. Conclusion Both are associated adults, notable gender differences effects. Targeted health policies encourage improved while considering gender-specific needs, essential reduce enhance quality life population.

Language: Английский

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Knowledge map of programmed cell death in esophageal cancer: a bibliometric analysis

Discover Oncology, Journal Year: 2025, Volume and Issue: 16(1)

Published: April 24, 2025

This study aimed to delineate the evolving knowledge structure of programmed cell death in esophageal cancer and identify key thematic trends, influential collaborations, emerging areas for future research. A bibliometric approach was applied 2677 publications retrieved from Web Science Core Collection (2000-2024). Three complementary tools-CiteSpace, VOSviewer, bibliometrix-were employed visualize co-citation networks, detect citation bursts, map collaborative patterns among authors, institutions, countries. Inclusion criteria focused on articles reviews that addressed conjunction with apoptosis, necroptosis, pyroptosis, ferroptosis, autophagy, or related pathways. Publication outputs grew markedly, reflecting a shift early investigations basic apoptotic mechanisms broader explorations ferroptosis. China led publication volume citations, driven by substantial governmental funding large clinical cohorts. The United States Japan also contributed significantly, forming international research networks spanned Asia Europe. Leading particularly Zhengzhou University, demonstrated extensive collaborations. Journals such as Oncology Letters Reports were prominent outlets new findings, while highly cited references highlighted hypoxia, immune checkpoint blockade, gene-editing strategies. Keyword analyses revealed ascendance immuno-oncology, network pharmacology, translational applications targeting multiple regulated Bibliometric evidence underscores rapid expansion multidisciplinary integrates diverse pathways cancer. Continued leveraging advanced genomics immunologic strategies, are poised accelerate breakthroughs enable more personalized, effective therapies.

Language: Английский

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The gender difference in the effects of air pollution on the risk of spinal osteoarthritis in Chinese middle-aged and older adults: a prospective cohort study in China

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: April 30, 2025

This study aimed to investigate whether exposure multiple ambient air pollutants (PM1, PM2.5, PM10, O₃, and NO₂) elevates the risk of spinal osteoarthritis among middle-aged older adults in China, further determine if there are gender-specific differences vulnerability. A total 7,663 participants aged 45 years older, drawn from China Health Retirement Longitudinal Study (CHARLS), were followed 2011 2020. Individuals free at baseline included. Annual mean concentrations PM1, NO₂ extracted High Air Pollutants (CHAP) dataset a 1 km resolution (10 for some years). Spinal was identified via self-reported, physician-diagnosed cases involving spine. Time-varying Cox proportional hazards regression models used evaluate hazard ratios (HR) 95% confidence intervals (CI) per 10 μg/m3 increase pollutant concentrations. All analyses accounted demographic, socioeconomic, lifestyle, spatial/seasonal factors, explored potential effect modification by gender. During median 7-year (IQR: 4-9 years) follow-up, 1,556 newly reported osteoarthritis. After adjusting confounders, each increment associated with significant rise incidence (13.8, 6.8, 5.1, 17.4%, respectively), while O₃ showed weaker non-significant (1.1%). Notably, stratified revealed that female exhibited pronounced vulnerability exposures, whereas associations males not statistically significant. prospective indicates higher particulate matter traffic-related may contribute an elevated osteoarthritis, particularly women. These findings underscore importance incorporating musculoskeletal health into quality management highlight value targeted interventions-such as reducing pollution monitoring high-risk groups-to mitigate burden rapidly urbanizing areas.

Language: Английский

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Mediation factors of the association between coronary heart disease and physical activity among rural residents: a cross-sectional study

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: May 19, 2025

There is evidence that physical and chemical factors risky lifestyle behaviours are significantly correlated with elevated susceptibility to coronary heart disease (CHD). Nevertheless, the mediation of this relationship little investigated. This article attempts assess mediating between CHD activity (PA) in rural residents. We conducted a cross-sectional study 9,004 permanent residents regions Xinxiang County, Henan Province. The correlation PA was evaluated using logistic regression model, as well association its associated risk factors. robustness outcomes through sensitivity analysis. were explored results showed (0.72, 95%CI:0.56-0.95), levels fasting insulin (FINS), total cholesterol (TC), blood glucose (GLU) (-0.92, 95%CI: (-1.48, -0.37), 0.08, (0.01, 0.15), -0.17, (-0.28, -0.06)). FINS, TC GLU had significant effects on (1.00, (-0.0028, 0.0000), 1.00, (-0.0016, (-0.0014, 0.0000)). In populations, CHD, possibly mediated by GLU, rather than relying solely direct PA.

Language: Английский

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Prognostic effect of body roundness index on all-cause mortality among US older adults

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: May 22, 2025

The Body Rounds Index (BRI) is an anthropometric indicator specifically developed to evaluate individual's obesity level, particularly emphasizing central or abdominal obesity. This study aimed explore the relationship between BRI and all-cause mortality in older U.S. adults. research sample comprised individuals aged 65 from National Health Nutrition Examination Survey (NHANES), eligible for analyses 1999 2018. We utilized Cox regression analyses, restricted cubic spline (RCS), threshold effects analysis, Kaplan-Meier curves, subgroup were conducted assess how correlates with among adults To further ensure robustness of our findings, we sensitivity analyses. Among 5371 (age ≥ 65), average age 72.45 (standard deviation [SD]:5.65) years, 2884 (60%) women. During follow-up period, there 2781 deaths all causes participants. After adjusting covariates, a U-shaped association was identified cause mortality. Compared less than 4.457, 4.457 5.538 associated 19% reduction likelihood any (HR = 0.81, 95% CI 0.69-0.95). A 6.888 linked 8% risk 0.92, 0.79-1.07), while exceeding showed 1% increase this 1.01, 0.87-1.17). RCS analysis indicated turning point located at 4.546, correlations observed both before after point. NHANES-based highlights adults, suggesting that has predictive value outcomes. findings offer compelling support utilizing as non-invasive screening tool.

Language: Английский

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