Associations between oxidative balance score and chronic kidney disease events in type 2 diabetes mellitus patients: a cross‑sectional study
Yunhe Ding,
No information about this author
Liwen Liu,
No information about this author
Zhen Feng
No information about this author
et al.
Research Square (Research Square),
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 14, 2025
Abstract
The
Oxidative
Balance
Score
(OBS)
serves
as
a
comprehensive
metric
that
amalgamates
17
dietary
and
lifestyle
elements
to
evaluate
antioxidant
status.
Thi
research
aims
investigate
the
association
between
OBS
prevalence
of
chronic
kidney
disease
(CKD)
in
individuals
diagnosed
with
type
2
diabetes
mellitus
(T2DM).
This
cross-sectional
study
included
data
from
National
Health
Nutrition
Examination
Survey
(NHANES)
conducted
2007
2018.
CKD
was
determined
using
albumin-to-creatinine
ratio(ACR)and
estimated
glomerular
filtration
rate
(eGFR).
Patients
were
grouped
into
low,
moderate,
high-risk
categories
based
on
their
risk
levels.
variable
transformed
continuous
format
quartiles
for
subsequent
analysis.
Weighted
multivariable
logistic
regression
restricted
cubic
spline
models
employed
examine
relationship.
Subgroup
analyses
interaction
tests
assessed
findings'
robustness.
results
indicated
negative
correlation
risk.
Individuals
higher
exhibited
decreased
(OR
0.69,
95%
CI:
0.57–0.85,
P
=
0.0003).
A
notable
identified
among
low-risk
moderate-risk
groups.
subgroup
analysis
stable,
no
significant
interactions
detected
subgroups.
Increased
levels
correlated
CKD.
Improving
capacity
through
modifications
enhance
may
serve
an
effective
strategy
prevention.
Language: Английский
Association between the oxidative balance score and estimated glomerular filtration rate: 2007-2018 NHANES
Mingda Wu,
No information about this author
Cuiting Dong,
No information about this author
Zhen Yang
No information about this author
et al.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(20), P. e39230 - e39230
Published: Oct. 1, 2024
:Oxidative
stress
is
closely
associated
with
the
estimated
glomerular
filtration
rate
(eGFR)
levels.
A
comprehensive
indicator
for
evaluating
dietary
and
lifestyle
exposures
to
oxidative
Oxidative
Balance
Score
(OBS),
higher
OBS
suggesting
more
substantial
antioxidant
exposures.
The
aim
of
this
study
explore
relationship
between
eGFR
total
20,285
subjects
were
selected
from
National
Health
Nutrition
Examination
Survey
(NHANES)
2007-2018.
One-way
multifactorial
linear
regression
analyses
used
assess
association
eGFR.
levels
was
also
assessed
using
restricted
cubic
splines
(RCS)
analysis.
significantly
positively
correlated
levels,
values
susceptible
in
males
than
females.
Our
findings
suggest
that
scores
may
be
highlighting
importance
adhering
an
diet
lifestyle,
which
can
help
prevent
kidney
disease.
Language: Английский