Association between METS-IR and female infertility: a cross-sectional study of NHANES 2013–2018

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: Feb. 28, 2025

Background Obesity and metabolic syndrome are significant contributors to infertility in women closely associated with insulin resistance (IR). The score for (METS-IR) is a new, non-insulin-based fasting index used measure IR. However, the potential of METS-IR as predictive indicator female risk has not been established. This study aimed explore association between infertility. Methods cross-sectional data from National Health Nutrition Examination Survey (NHANES) 2013 2018. We conducted multivariate logistic regression, restricted cubic spline (RCS), threshold effect analyses investigate relationship Results According self-reported data, 188 (12.20%) participants were classified infertile. A significantly higher proportion elevated found have Multivariable regression analysis revealed that was increased infertility, irrespective independent variable by continuous variables or tertiles fully adjusted model (Model 3, variable: OR = 1.02, 95% confidence interval (CI):1.01–1.04, p 0.005; tertile 3 vs. 1: 2.00, CI 1.21–3.28, 0.0128, trend =0.0126). RCS indicated linear correlation ( 0.121), further supported this 0.136). Moreover, above inflection point 32.94, increasing level < 0.0001). Conclusion Our results suggest high levels positively among reproductive-aged females United States.

Language: Английский

Correlation of alternative healthy eating index with risk of frailty among metabolic syndrome individuals: a cross-sectional study

Aging Clinical and Experimental Research, Journal Year: 2025, Volume and Issue: 37(1)

Published: March 17, 2025

Abstract Background Mounting evidence identifies diet quality as a frailty modifying factor. Individuals suffering from metabolic syndrome (MetS) are more likely to be affected by frailty. Therefore, our research sought explore the relationship of Alternative Healthy Eating Index (AHEI) with risk among patients MetS. Methods National Health and Nutrition Examination Survey (NHANES) data 2005 2018 were gathered. Frailty (FI) was utilized for assessment status. Weighted multivariate logistic regression model adopted investigating association AHEI Subgroup analysis, interaction test restricted cubic spline (RCS) also performed in this study. Results When covariates considered entirely adjusted for, higher scores exhibited significant reduced (OR = 0.99,95%CI 0.981–0.998, P 0.022). Relative participants belonging lowest quartile(Q1), that individuals highest quartile(Q4) decreased 32% 0.68, 95% CI 0.51–0.92, 0.01). Additionally, negative persisted all subgroup analyses, which indicates reliability relationship. Conclusion For MetS, reduce developing This investigation provides valuable knowledge could treating MetS clinically guiding healthy eating program development.

Language: Английский