Tracing the path from conservation to expansion evolutionary insights into NLR genes in oleaceae DOI Creative Commons

Sumbal Parvez,

Maryam Asif,

Alizay Ahmad

et al.

BMC Plant Biology, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 26, 2025

The Oleaceae family, encompassing key genera such as Fraxinus (ash trees), Olea (olives), Jasminum (jasmine), Syringa (lilac), and Forsythia, plays a crucial ecological economic role. Despite their importance, the evolutionary dynamics immune system adaptations of NLR (Nucleotide binding leucine-rich repeats) gene family remain largely unexplored. This study employs high-throughput comparative genomics to investigate evolution across family. genus is widely distributed both New Old Worlds, with 23 distinct species analyzed in this study. Our results reveal predominant strategy conservation these species. Geographical adaptation has played significant role, particularly World ash tree species, which exhibit dynamic patterns expansion contraction within last 50 million years. Notably, genes acquired from an ancient whole genome duplication event (~ 35 Mya) have been retained lineages. In contrast, (olives) undergone extensive driven by recent duplications birth novel families. These differences likely enhance Olea's ability recognize diverse pathogens through expansions, while maintains specialized responses conserved genes, potential trade-offs pathogen energy efficiency. terms distribution, all show enhanced pseudogenization TIR-NLRs CCG10-NLR. However, RNA-seq expression analysis olive suggests that partial despite incomplete structure, may play important roles plant responses. provides comprehensive offering insights into adaptive mechanisms response genera.

Language: Английский

NRC Immune receptor networks show diversified hierarchical genetic architecture across plant lineages DOI
Foong‐Jing Goh, Ching‐Yi Huang, Lida Derevnina

et al.

The Plant Cell, Journal Year: 2024, Volume and Issue: 36(9), P. 3399 - 3418

Published: June 26, 2024

Plants' complex immune systems include nucleotide-binding domain and leucine-rich repeat-containing (NLR) proteins, which help recognize invading pathogens. In solanaceous plants, the NRC (NLR required for cell death) family includes helper NLRs that form a genetic network with multiple sensor to provide resistance against However, evolution function of networks outside plants are currently unclear. Here, we conducted phylogenomic macroevolutionary analyses comparing identified from different asterid lineages found expanded significantly in most lamiids but not Ericales campanulids. Using transient expression assays Nicotiana benthamiana, showed simple campanulids, have high complexity lamiids. Phylogenetic grouped into three NRC0 subclades conserved, several family-specific show signatures diversifying selection. Functional revealed members partially interchangeable, whereas lack interchangeability. Our findings highlight distinctive evolutionary patterns asterids potential insights transferring disease across plant lineages.

Language: Английский

Citations

8
Bioinformatics and expression analysis of the NRL gene family in Populus trichocarpa DOI
Raphael Dzinyela, Delight Hwarari, Abdul Razak Alhassan

et al.

Genetic Resources and Crop Evolution, Journal Year: 2024, Volume and Issue: unknown

Published: May 11, 2024

Language: Английский

Citations

4
NRC immune receptor networks show diversified hierarchical genetic architecture across plant lineages DOI Creative Commons
Foong‐Jing Goh, Ching‐Yi Huang, Lida Derevnina

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Oct. 27, 2023

Abstract Plants developed sophisticated immune systems with nucleotide-binding domain and leucine-rich repeat-containing (NLR) proteins to repel invading pathogens. The NRC (NLR required for cell death) family includes helper NLRs that form a complex genetic network multiple sensor provide resistance against pathogens of solanaceous plants. However, the evolution function networks outside plants is currently unknown. We conducted phylogenomic macroevolutionary analyses comparing identified from different asterids lineages found expanded significantly in most lamiids but not Ericales campanulids. Using transient expression assays Nicotiana benthamiana , we show are simple campanulids, high complexity lamiids. Phylogenetic grouped into three NRC0 subclades conserved, several family-specific signatures diversifying selection. Functional revealed members partially interchangeable, whereas lack interchangeability. Our findings highlight distinctive evolutionary patterns potential insights transferring disease across plant lineages.

Language: Английский

Citations

10
Tracing the path from conservation to expansion evolutionary insights into NLR genes in oleaceae DOI Creative Commons

Sumbal Parvez,

Maryam Asif,

Alizay Ahmad

et al.

BMC Plant Biology, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 26, 2025

The Oleaceae family, encompassing key genera such as Fraxinus (ash trees), Olea (olives), Jasminum (jasmine), Syringa (lilac), and Forsythia, plays a crucial ecological economic role. Despite their importance, the evolutionary dynamics immune system adaptations of NLR (Nucleotide binding leucine-rich repeats) gene family remain largely unexplored. This study employs high-throughput comparative genomics to investigate evolution across family. genus is widely distributed both New Old Worlds, with 23 distinct species analyzed in this study. Our results reveal predominant strategy conservation these species. Geographical adaptation has played significant role, particularly World ash tree species, which exhibit dynamic patterns expansion contraction within last 50 million years. Notably, genes acquired from an ancient whole genome duplication event (~ 35 Mya) have been retained lineages. In contrast, (olives) undergone extensive driven by recent duplications birth novel families. These differences likely enhance Olea's ability recognize diverse pathogens through expansions, while maintains specialized responses conserved genes, potential trade-offs pathogen energy efficiency. terms distribution, all show enhanced pseudogenization TIR-NLRs CCG10-NLR. However, RNA-seq expression analysis olive suggests that partial despite incomplete structure, may play important roles plant responses. provides comprehensive offering insights into adaptive mechanisms response genera.

Language: Английский

Citations

0