Interplay Between Diabetes, Obesity and Glioblastoma Multiforme, and the Role of Nanotechnology in Its Treatment

Journal of Nanotheranostics, Journal Year: 2025, Volume and Issue: 6(1), P. 7 - 7

Published: Feb. 27, 2025

A very aggressive and deadly brain cancer, glioblastoma multiforme (GBM) poses formidable obstacles to effective therapy. Despite advancements in conventional therapies like surgery, chemotherapy, radiation therapy, the prognosis for GBM patients remains poor, with limited survival outcomes. Nanotechnology is gaining popularity as a promising platform managing GBM, offering targeted drug delivery, improved therapeutic efficacy, reduced systemic toxicity. This review offers comprehensive analysis of current approach using nanotechnology-based interventions. study explored various nanocarrier (NC) systems polymeric nanoparticles, liposomes, dendrimers, micelles, mesoporous silica nanoparticles precision well efficacy encapsulating delivering agents tumors. Methods improving delivery into cells are described this study, including novel modalities such convection-enhanced intranasal administration, magnetic hyperthermia, peptide-guided immune liposomes. It also explores influence diabetes obesity on rates, suggesting that glucose levels metformin may improve patient The discussion focuses nanotechnology-enabled highlighting challenges opportunities implementing these technologies clinical practice. highlights potential nanotechnology metabolic modulation transforming treatment strategies. To further understand how factors impact develop innovative treatments mellitus, more necessary.

Language: Английский

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Nanotechnology-Based Therapies for Preventing Post-Surgical Adhesions

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(3), P. 389 - 389

Published: March 19, 2025

Adhesions are the body’s natural response to various inflammatory causes, with surgery being most common cause. However, formation of postoperative adhesions can lead significant complications, including intestinal obstruction and chronic pain. To prevent such complications associated adhesions, developing effective strategies for adhesion prevention has been a major focus research. Currently, several therapeutic models have developed achieve this objective. These include pharmaceuticals, inert polymers, functional biomaterials, nanotherapeutics. Among developed, nanotherapeutics, though still in its early stages, shown promise as potential approach. Other adverse side effects related their application. On other hand, nanotherapeutic able overcome limitations provide own set unique advantages. Hence, nanotherapeutics represents promising area further Further efforts should be made refine existing clinical application while also addressing safety ethical concerns use medical practice. Therefore, article aims review approaches explore regulatory pathways, discuss concerns.

Language: Английский

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Personalized Nanomedicine-Mediated immune regulation for Anti-Rejection in organ transplantation

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 125450 - 125450

Published: March 1, 2025

Language: Английский

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The current use of nanotechnology in the fight against antimicrobial resistance: promising approaches to global health challenge

Journal of Nanoparticle Research, Journal Year: 2025, Volume and Issue: 27(4)

Published: April 1, 2025

Language: Английский

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Nanozymes in biomedicine: Unraveling trends, research foci, and future trajectories via bibliometric insights (from 2007 to 2024)

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142798 - 142798

Published: April 1, 2025

Language: Английский

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