Heliyon, Journal Year: 2024, Volume and Issue: 10(17), P. e36509 - e36509
Published: Aug. 28, 2024
Language: Английский
Current Pharmaceutical Analysis, Journal Year: 2024, Volume and Issue: 21(1), P. 20 - 32
Published: Dec. 1, 2024
Language: Английский
Citations
12
Human Vaccines & Immunotherapeutics, Journal Year: 2025, Volume and Issue: 21(1)
Published: Feb. 17, 2025
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease of autoimmune origin. T cells play crucial roles in the initiation and progression RA. Although bibliometric methods have been widely used to synthesize knowledge trajectories across different biomedical fields, it has hardly underscore trends relation cell This study delineate evolution research on Data were sourced from Web Science™ Core Collection scientometrically analyzed using CiteSpace VOSviewer. From 2014 2023, 7037 papers RA retrieved. The number annual publications stable between 600 800, citation frequency continues rise. United States, China, Kingdom Japan most productive countries. Karolinska Institute, Harvard Medical School institutions that published papers. Wei W, Cho ML, Park SH prolific authors. Mclnnes IB Smolen JS frequently cited journals with articles are Frontiers Immunology, Arthritis Research & Therapy, Rheumatology. Current hotspots include pathogenic factors targeted biological therapy, immune mechanisms, bone destruction mechanisms. current frontiers this field gut microbiota, identification, fibroblast-like synoviocytes, biologic mesenchymal stem cells, risk. work provides new insights into scientific clinical application develop therapeutic targets for
Language: Английский
Citations
1
Frontiers in Immunology, Journal Year: 2022, Volume and Issue: 13
Published: Oct. 27, 2022
Objective Tumor necrosis factor (TNF), a crucial cytokine, has important research value in post-stroke neuroinflammation (PSN). We analyzed the studies that have been conducted this area and used bibliometric methods to predict hotspots identify trends regarding TNF PSN. Methods Publications were accessed at Science Citation Index Expanded 1975-2021 (SCI expanded), Web of Core Collection (WoSCC), on May 1, 2022. Additionally, software such as CiteSpace VOSviewer utilized for analyses. Results In total, 1391 original articles reviews PSN published from 2003 2021 identified. An upward trend was observed number publications These primarily 57 countries 1446 institutions, led by China United States with leading (NP) US citations (NC). The League European Research Universities (LERU) Journal Neuroinflammation, respectively most prolific branches journals. Zhang, John H. papers Finsen, Bente had cited papers. One paper Kettenmann, 2011 reached highest level Global Score (GCS). keyword co-occurrence reference co-citation analyses suggest poststroke therapy potential mechanistic pathways are topics related recent years. Reference burst detection suggests new after 2015, focusing pathway modulation discovery therapeutic targets, suggesting substantial development study research. Conclusion present analysis shows continuous increasing literature PSN, plays an role involves multiple immune mechanisms may contribute target neuroprotective therapeutics stroke. Prior 2011, focused discovering specific years mainly targeted exploration signaling pathways. Future prospects lie finding key targets
Language: Английский
Citations
17
Stem Cell Reviews and Reports, Journal Year: 2025, Volume and Issue: unknown
Published: April 21, 2025
One of the major global causes death and disability is ischemic stroke (IS). Mesenchymal stem cells (MSCs) emerge as a cell-based therapy for numerous diseases. Recently, research on role MSCs in has developed rapidly worldwide. Bibliometric analysis IS not yet been published, though. Through bibliometric analysis, aim this study was to assess current state field worldwide identify important results, areas, emerging trends. Publications related from January 1, 2002, December 31, 2022, were obtained Web Science Core Collection (WoSCC). We used HistCite, VOSViewer, CiteSpace, Bibliometrix visualization. employed Total Global Citation Score (TGCS) impact publications. The included total 2,048 1,386 papers authored by 200 individuals across organizations 72 countries, published 202 journals. Cesar V Borlongan most documents among high-productivity authors. Michael Chopp author with highest average number citations per paper, an paper citation time 118.54. found that starting 2008. Neurosciences productive journals, Chinese researchers have produced subject. cited article "Systemic administration exosomes released mesenchymal stromal promotes functional recovery neurovascular plasticity after rats". This uses both numbers descriptions thoroughly review IS. information provides valuable experience carry out MSCs' work
Language: Английский
Citations
0
Human Vaccines & Immunotherapeutics, Journal Year: 2025, Volume and Issue: 21(1)
Published: May 17, 2025
Nectin-4 has emerged as a pivotal therapeutic target for antibody-drug conjugates (ADCs), particularly in advanced urothelial carcinoma (aUC) research. Although extensive literature been reported on Nectin-4, it is worth noting that no studies have yet systematically investigated the hotspots, cutting-edge directions, and tissue expression of this using combination bibliometric analysis bioinformatics methods. Findings reveal growing interest Nectin-4's role cancer immunotherapy ADC development. Urothelial remains primary focus, with breast bladder cancers gaining traction. Key research priorities include optimizing safety profiles, managing cutaneous adverse events. Notably, dual targeting strategies combining TROP-2 show promise next-generation therapies. The study highlights evolving clinical needs, from validation to treatment optimization, positioning versatile biomarker bridging multiple domains. These insights emphasize protein's translational potential while underscoring importance balancing efficacy toxicity management
Language: Английский
Citations
0
Heliyon, Journal Year: 2024, Volume and Issue: 10(7), P. e29199 - e29199
Published: April 1, 2024
Tumor vascular normalization profoundly affects the advancement of cancer therapy. Currently, with rapid increase in research on tumor normalization, few analytical and descriptive studies have investigated trends its development, key power, present hotspots, future outlooks. In this study, articles reviews published between January 1, 2003, October 29, 2022 were retrieved from Web Science database. Subsequently, trends, countries/regions, institutions, authors, journals, references, keywords analyzed based traditional bibliometric laws (such as Price's exponential growth, Bradford's, Lotka's, Zipf's). Our results showed that last two decades seen an research. USA emerged preeminent contributor to field, boasting highest H-index accruing greatest quantity publications citations. Among Massachusetts General Hospital Harvard University made significant contributions, Professor RK Jain was identified a leader field. Out 583 academic
Language: Английский
Citations
3
Heliyon, Journal Year: 2024, Volume and Issue: 10(12), P. e33219 - e33219
Published: June 1, 2024
BackgroundBreast cancer is the most widespread malignant tumor worldwide. Single-cell sequencing technology offers novel insights and methods to understand onset, progression, treatment of tumors. Nevertheless, there currently an absence a thorough unbiased report on comprehensive research status single-cell in breast cancer. This study seeks summarize quantify dynamics trends by bibliometric analysis.MethodsResearch articles reviews related were selected from WoSCC database. Visualization data regarding countries, institutions, authors, references, keywords was performed CiteSpace VOSviewer software.Results583 analyzed this study. The quantity publications has been increasing annually. These studies originate 302 institutions 46 with YMAX S WICHA producing WANG Y being cited author. Nature Communications researched journal, while holds highest number citations. journals predominantly cover topics molecular/biological/immunological fields. Moreover, analysis reference keyword bursts revealed that current area are primarily centered "clonal evolution," "tumor microenvironment," "immunotherapy."ConclusionBreast rapidly growing scientific interest. Future requires more frequent in-depth collaborations among authors. Furthermore, "immunotherapy" likely become major focal points upcoming sequencing.
Language: Английский
Citations
2
Heliyon, Journal Year: 2023, Volume and Issue: 9(8), P. e18843 - e18843
Published: Aug. 1, 2023
Increasing evidence indicated that mitophagy might play a crucial role in the occurrence and progression of liver diseases. In order to enhance our understanding intricate relationship between diseases, comprehensive bibliometric analysis existing literature this field was conducted. This aimed identify key trends, potential areas future research, forecast development specific field. We systematically searched Web Science Core Collection (WoSCC) for publications related diseases from 2000 2022. conducted data visualization through VOSviewer CiteSpace. The publication growth revealed substantial increase articles published over past years, indicating mitophagy's growing interest significance China USA emerged as leading contributors number papers, with 294 194 independent respectively. Exploring mechanism initiation procession main content studies field, Parkin-independent mediated has attracted much attention recently. "Lipid metabolism," "cell death," "liver fibrosis" "oxidative stress" were primary keywords clusters. Additionally, "nlrp3 inflammasome", "toxicity" "nonalcoholic steatohepatitis" emerging research hotspots area have continue be focal investigation future. study represents first systematic on 20 years. By providing an overview identifying current sheds light critical paves way
Language: Английский
Citations
6
Fundamental and Clinical Pharmacology, Journal Year: 2023, Volume and Issue: 38(2), P. 208 - 224
Published: Sept. 12, 2023
Astragaloside IV has emerged as a pharmaceutical monomer with great medical applications and potential. many effects such improving myocardial ischemia, cerebral ischemia-reperfusion injury, anti-inflammatory, analgesic, antiviral, promoting lymphocyte proliferation, antitumor effects. However, there are few bibliometric studies on astragaloside IV.
Language: Английский
Citations
6
Renal Failure, Journal Year: 2024, Volume and Issue: 46(2)
Published: Nov. 21, 2024
Macrophages play a variety of widely concerned roles in the process chronic kidney disease (CKD). To further understand research hotspots and development trends regarding relationship between macrophages CKD, role occurrence progression CKD was summarized by bibliometrics this study.
Language: Английский
Citations
2