Modifications of miRNAs in intervertebral disc degeneration: a key to the future development of genetic-based therapies DOI
Fariborz Ghaffarpasand, Sirous Sarhadi, Mohammad Hesam Alavi

et al.

Epigenomics, Journal Year: 2023, Volume and Issue: 15(5), P. 271 - 281

Published: March 1, 2023

Intervertebral disc degeneration (IDD) is the main cause of low back pain, which a healthcare concern associated with high social and economic burden. The current medical surgical therapies are inadequate ineffective. Several miRNAs have been identified that modulate (via up- or down-regulation) pathogenesis IDD through various signaling pathways. Understanding nature this regulation their pathways will enable researchers to manipulate miRNA develop miRNA-based therapies. development opens future window decrease process regenerate intervertebral disc. In near future, obstacles be overcome these move from bench bedside.

Language: Английский

The Elevated Serum Levels of Beta‐1,4‐Galactosyltransferase 1 Have Diagnostic Value in Patients With Rheumatoid Arthritis DOI
Yulin Zhang,

Jiaqian Zhang,

Min Dong

et al.

International Journal of Rheumatic Diseases, Journal Year: 2024, Volume and Issue: 27(12)

Published: Dec. 1, 2024

Language: Английский

Citations

0
Review of interleukin-6 polymorphisms in rheumatoid arthritis: a genetic implications DOI

Dhulfiqar Nidhal Alhilali,

Samer Imad Mohammed, Faiq I. Gorial

et al.

Journal Of Advanced Pharmacy Education And Research, Journal Year: 2024, Volume and Issue: 14(3), P. 109 - 117

Published: Jan. 1, 2024

Language: Английский

Citations

0
Modifications of miRNAs in intervertebral disc degeneration: a key to the future development of genetic-based therapies DOI
Fariborz Ghaffarpasand, Sirous Sarhadi, Mohammad Hesam Alavi

et al.

Epigenomics, Journal Year: 2023, Volume and Issue: 15(5), P. 271 - 281

Published: March 1, 2023

Intervertebral disc degeneration (IDD) is the main cause of low back pain, which a healthcare concern associated with high social and economic burden. The current medical surgical therapies are inadequate ineffective. Several miRNAs have been identified that modulate (via up- or down-regulation) pathogenesis IDD through various signaling pathways. Understanding nature this regulation their pathways will enable researchers to manipulate miRNA develop miRNA-based therapies. development opens future window decrease process regenerate intervertebral disc. In near future, obstacles be overcome these move from bench bedside.

Language: Английский

Citations

1