Phytotherapy Research,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 18, 2025
ABSTRACT
Insomnia,
a
prevalent
sleep
disorder,
significantly
impacts
global
health.
While
Western
medications
provide
temporary
relief,
their
risks
of
dependency
and
cognitive
impairment
have
spurred
the
search
for
safer
alternatives.
Traditional
Chinese
Medicine
(TCM)
offers
promising
approach
to
treating
insomnia
by
focusing
on
harmonizing
balance
Yin
Yang
functions
internal
organs.
This
review
explores
recent
research
advances
in
TCM
treatment,
integrating
classical
theories
with
modern
scientific
understanding
key
pathological
mechanisms,
including
neurotransmitter
regulation
(GABA,
monoamines),
immune‐inflammatory
responses,
HPA
axis,
interactions
gut
microbiota.
Growing
clinical
evidence
supports
effectiveness
prescriptions
treatments
like
acupuncture
improving
quality,
particularly
when
combined
enhance
efficacy
reduce
dependency.
However,
also
has
its
limitations.
Future
directions
should
focus
modernizing
applications,
addressing
comorbidities
associated
insomnia,
exploring
role
microbiota,
optimizing
medicinal
edible
homologous
products.
By
traditional
knowledge
cutting‐edge
technologies,
holds
great
potential
advancing
personalized
effective
globally.
Frontiers in Neurology,
Journal Year:
2025,
Volume and Issue:
16
Published: March 12, 2025
Objective
The
aim
of
this
study
was
to
comprehensively
evaluate
the
efficacy
acupuncture
combined
with
language
training
in
treatment
aphasia
children
cerebral
palsy
(CP).
Methods
We
searched
eight
electronic
databases
from
their
inceptions
July
1,
2024
for
randomized
controlled
trials
(RCTs)
CP.
evaluation
methodological
quality
RCTs
incorporated
adhered
guidelines
provided
by
Cochrane
risk-of-bias
tool
(ROB2).
Grading
Recommendations
Assessment,
Development
and
Evaluation
Approach
(GRADE)
used
certainty
evidence
each
outcome.
heterogeneity
included
literature
tested
using
Review
Manager
5.4
software,
while
publication
bias
estimated
funnel
plots
Egger’s
tests
STATA15.1.
A
trial
sequential
analysis
(TSA)
performed
test
robustness
conclusiveness
our
results.
Results
In
study,
we
encompassed
a
total
56
randomised
encompassing
4,683
participants.
majority
these
were
characterized
either
high
or
uncertain
risk
bias,
predominantly
due
omission
blinding
within
experimental
setups.
Meta-analysis
showed
that
significantly
better
than
alone
improving
clinical
efficiency
(RR:
1.25;
95%
CI:
1.21,
1.29;
p
<
0.00001).
subgroup
different
types
revealed
acupuncture,
electroacupuncture,
scalp
auricular
point
seed-pressing
all
significant
improvement
Acupuncture
could
improve
adaptive
behaviour
(MD:
7.46;
3.67,
11.26;
=
0.0001),
verbal
7.79;
5.66,
9.92;
0.00001),
fine
motor
4.66;
1.28,
8.03;
0.007),
personal
social
6.47;
2.38,
10.55;
0.002);
it
also
more
effective
comprehension
developmental
quotient
(SMD:
2.02;
1.54,
2.50;
expressive
development
2.40;
1.76,
3.03;
assessment
dysarthria
0.40;
0.11,
0.69;
oral
function
2.63;
1.36,
3.90;
0.0001).
Conclusion
be
an
Due
low
very
heterogeneity,
rigorous
are
needed
verify
effect
management
Systematic
review
registration
https://www.crd.york.ac.uk/PROSPERO/view/CRD42024501328
,
identifier
CRD42024501328.
Frontiers in Oncology,
Journal Year:
2025,
Volume and Issue:
15
Published: March 17, 2025
Although
acupuncture
is
recommended
for
managing
breast
cancer-related
hot
flashes,
the
level
of
evidence
limited.
With
updating
randomized
controlled
trials,
it
necessary
to
reassess
its
efficacy.
To
assess
effectiveness
in
treatment
flashes
patients
with
cancer.
Up
March
2024,
we
retrieved
data
from
nine
databases
and
used
Stata
software
(version
14.0,
version
17.0)
RevMan
5.3)
conduct
a
meta-analysis.
The
Cochrane
Collaboration's
risk
bias
assessment
tool
was
methodological
bias,
GRADEpro
GDT
online
evaluation.
In
total,
11
trials
(RCTs)
involved
963
participants
were
included
result
revealed
that
RCTs
exhibited
high
primarily
attributable
deficiencies
randomization
blinding
methods.
results
primary
meta-analysis
indicated
can
improved
flash
symptom
scale
score
(SMD,
-0.54;
95%
CI,
-0.83
-0.24;
P
<
0.05).
However,
does
not
reduce
frequency
flashes(SMD,
-0.20;
-0.75
0.36;
=
0.48).
Further
subgroup
analyses,
including
type
control
group
duration
needle
retention,
etc.
showed
different
results,
highlighting
necessity
further
research.
Sensitivity
analysis
confirmed
reliability
these
finding.
addition,
due
various
issues,
low.
cancer
shows
potential,
efficacy
still
lacking
factors
such
as
significant
differences
between
studies,
more
high-quality
are
needed
confirm
acupuncture.
https://www.crd.york.ac.uk/prospero/,
identifier
CRD42024531542.
Bone Reports,
Journal Year:
2025,
Volume and Issue:
unknown, P. 101842 - 101842
Published: April 1, 2025
Bone
fracture
is
a
common
orthopedic
condition
that
affects
millions
of
people
worldwide.
The
management
frequently
involves
surgery,
which
requires
hospitalization.
Patients
with
fractures
often
have
risk
developing
complications,
including
pain,
inflammation,
infection,
delayed
healing,
thrombosis,
and
organ
failure.
Acupuncture
widely
used
for
conditions
such
as
respiratory
issues,
urinary
system
disorders,
gastrointestinal
discomfort.
In
this
retrospective
study,
we
evaluated
the
effectiveness
acupuncture
in
reducing
postoperative
complications
patients.
Using
TriNetX
platform,
identified
individuals
hospitalized
their
first
surgery
performed
1:
1
propensity
score
matching.
who
received
three
or
more
treatments
within
one
week
(n
=
433)
were
compared
to
those
none
433),
matching
based
on
age,
sex,
race,
BMI,
comorbidities,
medications
(standardized
mean
differences).
Postoperative
180
days
analyzed
using
percentages,
ratios,
odds
Kaplan-Meier
analysis
log-rank
tests,
hazard
all
reported
95
%
confidence
intervals
P-values.
Fourteen
patients
group
experienced
failure
3.2
%,
while
29
non-acupuncture
developed
6.7
%.
ratio
was
0.48
(95
CI
0.26-0.90)
OR
0.47
0.24-0.89).
found
significantly
higher
survival
probability
(log-rank
test
P
0.01;
HR
0.44,
95%CI
0.23-0.83).
appeared
potential
reduce
bone
Further
large-scale
studies
are
needed
provide
stronger
evidence.
Phytotherapy Research,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 18, 2025
ABSTRACT
Insomnia,
a
prevalent
sleep
disorder,
significantly
impacts
global
health.
While
Western
medications
provide
temporary
relief,
their
risks
of
dependency
and
cognitive
impairment
have
spurred
the
search
for
safer
alternatives.
Traditional
Chinese
Medicine
(TCM)
offers
promising
approach
to
treating
insomnia
by
focusing
on
harmonizing
balance
Yin
Yang
functions
internal
organs.
This
review
explores
recent
research
advances
in
TCM
treatment,
integrating
classical
theories
with
modern
scientific
understanding
key
pathological
mechanisms,
including
neurotransmitter
regulation
(GABA,
monoamines),
immune‐inflammatory
responses,
HPA
axis,
interactions
gut
microbiota.
Growing
clinical
evidence
supports
effectiveness
prescriptions
treatments
like
acupuncture
improving
quality,
particularly
when
combined
enhance
efficacy
reduce
dependency.
However,
also
has
its
limitations.
Future
directions
should
focus
modernizing
applications,
addressing
comorbidities
associated
insomnia,
exploring
role
microbiota,
optimizing
medicinal
edible
homologous
products.
By
traditional
knowledge
cutting‐edge
technologies,
holds
great
potential
advancing
personalized
effective
globally.
