BMJ Nutrition Prevention & Health, Journal Year: 2023, Volume and Issue: 6(Suppl 3), P. s8 - s19
Published: Dec. 1, 2023
As the global incidence of food allergies continues to rise, effective primary prevention strategies remain a public health priority. Eczema in early infancy is major risk factor for IgE-mediated allergies. Exposure allergens via inflamed skin promotes cascade allergic immune responses and increases By contrast, exposure gut likely induce oral tolerance. Landmark studies have demonstrated significant reduction egg peanut allergy response dietary introduction allergens. result, feeding guidelines countries with high shifted from recommending prolonged allergen avoidance policy around 6 months age, as part diverse complementary diet. Uncertainties regarding optimum timing specific allergens, well minimum frequency dose. Exclusive breast months, continuation 2 years, generally recommended but does not appear consistently prevent Perinatal intermittent supplementary cow’s milk-based formula may increase milk protein allergy. Maternal during pregnancy lactation effective. However, maternal consumption appears their preventive effect infant conjunction into Data on supplementation pregnant women, breastfeeding mothers infants vitamin D, omega-3 polyunsaturated fatty acids, prebiotics or probiotics purpose are insufficient make firm clinical recommendations. In eczema, combination regular emollient treatment additive effects, trials so far had mixed outcomes. Further combining interventions aiming restore disrupted barrier eczema provide new insights at-risk populations.
Language: Английский