The Role of Aryl Hydrocarbon Receptor in Skin Homeostasis: Implications for Therapeutic Strategies in Skin Disorders

Cell Biochemistry and Function, Journal Year: 2025, Volume and Issue: 43(2)

Published: Jan. 27, 2025

ABSTRACT The aryl hydrocarbon receptor (AhR), a ligand‐activated transcription factor, is extensively expressed in diverse human organs and plays pivotal role mediating the onset, progression, severity of numerous diseases. Recent research has explored substantial impact AhR on skin homeostasis related pathologies. As multi‐layered organ, comprises multiple cell populations that express AhR. In this review, we introduce various cells its barrier function. Furthermore, explore involvement development diseases, highlighting potential as therapeutic target for disorders. By targeting AhR, may open new avenues novel efficient disease treatments.

Language: Английский

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Molecular insights of vitamin D receptor SNPs and vitamin D analogs: a novel therapeutic avenue for vitiligo

Molecular Diversity, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Language: Английский

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Beyond skin deep: exploring the complex molecular mechanisms and holistic management strategies of vitiligo

Archives of Dermatological Research, Journal Year: 2025, Volume and Issue: 317(1)

Published: April 8, 2025

Language: Английский

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First Sighting of a Humpback Whale (Megaptera novaeangliae) with Leucism in the Colombian South Pacific

Thalassas An International Journal of Marine Sciences, Journal Year: 2025, Volume and Issue: 41(2)

Published: April 25, 2025

Language: Английский

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Short Communication: A novel hypopigmentation for southeast Pacific humpback whales

IWC Journal of Cetacean Research and Management, Journal Year: 2024, Volume and Issue: 25, P. 71 - 77

Published: July 17, 2024

Southeast Pacific humpback whales (Megaptera novaeangliae) migrate annually to breeding grounds in Machalilla, Ecuador, and Uramba Bahía Málaga, Colombia. This species usually displays a black/ grey body colouration with its dorsal caudal fins exposed above water. Between 2005 2023, these regions were studied photographed on 1,627 days. Results indicated that 29 have novel markings, including white spots, irregular circles sinuous lines, which resemble the paintings of 20th Century artist Jackson Pollock. While this ‘Pollock‐style’ pigmentation does not appear cause health problems, we recommend further studies evaluate origin effects.

Language: Английский

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Palmitoyl copper peptide and acetyl tyrosine complex enhances melanin production in both A375 and B16 cell lines

Biochemical and Biophysical Research Communications, Journal Year: 2024, Volume and Issue: 742, P. 151060 - 151060

Published: Nov. 28, 2024

Language: Английский

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