Centering prayer in the treatment of bipolar disorder DOI Creative Commons

Yanín Machado,

Mauricio Chinchilla,

Robert Hesse

et al.

World Journal of Advanced Research and Reviews, Journal Year: 2024, Volume and Issue: 21(3), P. 2314 - 2323

Published: March 30, 2024

Bipolar Disorder (BD), formerly manic-depressive illness or manic depression, is a lifelong mood disorder and mental health condition that causes intense shifts in mood, energy levels, thinking patterns, behavior. These can last for hours, days, weeks, months, interrupting the ability to carry out daily tasks. The manageable with medications, talk therapy, lifestyle changes, other treatments, but therapy results are unreliable many patients. Most faith traditions have two forms of prayer: discursive contemplative. believers practice prayer. Medical research has shown statistical healing effects prayer, there considerably less on contemplative Hesse reports method teaching CP by asking volunteer help demonstrate analogy between human Divine relationships following quoted phases., Therefore, we hypothesize might produce significant depression improvement BP Two neurologists double-blind diagnosed five patients complaining BD normal subjects. All cases expressed their belief God, so not non-theistic meditation. Patients will be free medication selected during depressive episodes. Among trait markers frontal alpha asymmetry,55,56, changes qEEG cordance. A very stable QEEG pattern, consisting asymmetry, was observed all Hence, this pattern used compare before after CP. Our main result showed focal left Alpha increment disappeared Conclusion: promising tool treating organizing function interplay among brain networks subserve Cognition-emotion interactions prefrontal cortex.

Language: Английский

Relationships among gut microbiota, plasma metabolites, and juvenile idiopathic arthritis: a mediation Mendelian randomization study DOI Creative Commons
Bingjun Gao, Zhe Wang,

Kunyao Wang

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: March 28, 2024

Objective The objective of this study is to investigate the causal relationship between gut microbiota and juvenile idiopathic arthritis, identify quantify potential role plasma metabolites as mediators. Methods Using summary-level data from genome-wide association studies, a two-sample Mendelian randomization was conducted involving 131 genus, 1,400 metabolites, arthritis. Additionally, two-step approach employed proportion effect on arthritis mediated by metabolites. Effect estimation primarily utilized Inverse Variance Weighting, with further validation using Bayesian weighted randomization. Results In our MR analysis, positive correlation observed Rikenellaceae risk while Dorea showed negative risk. Mediation analysis indicated that Furaneol sulfate levels acted mediator an indirect 19.94, 95% CI [8.86–31.03%]. Conclusion Our confirms specific microbial genus computes offering novel insights for clinical interventions in

Language: Английский

Citations

7
The Burden of Psychiatric Manifestations in Inflammatory Bowel Diseases: A Systematic Review With Meta-analysis DOI
Sara Massironi, Alessandro Pigoni, Elena Vegni

et al.

Inflammatory Bowel Diseases, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 12, 2024

Abstract Background Psychiatric disorders in patients with inflammatory bowel disease (IBD) represent a significant but uncertain facet of the disease, unsolved questions regarding their overall magnitude, impact on intestinal and whole burden psychiatric manifestations. Aim This systematic review summarizes evidence prevalence disorders, including depression, anxiety, bipolar disorder (BD), schizophrenia, among IBD. Methods A search across PubMed/MEDLINE, Embase, Scopus databases from January 2010 to 2023 was performed identify relevant studies. The focus studies exploring specific IBD compared general population that reported outcome measures. subsequent meta-analysis (MA) assessed strength association between these data reliability ensured through rigorous extraction quality assessment. Results Out 3,209 articles, 193 met inclusion criteria only 26 provided complete for comprehensive analysis. These showed significantly higher comorbidities population. MA depression (pooled OR 1.42, 95% CI = 1.33-1.52, P < .0001) anxiety 1.3, 1.22-1.44, .0001). BD 1.64, 1.20-2.24, considerable heterogeneity (I2 94.01%). Only 3 examined schizophrenia IBD, providing widely heterogeneous results, an inconclusive OR, estimated at 0.93 (95% 0.62-1.39, .73). Conclusions highlights high particularly patients, which exceeds rates is proving be important under-researched area. sparse contradictory requires further investigation. findings highlight need better understanding, early detection, tailored mental health interventions management improve patients’ life.

Language: Английский

Citations

5
Complex gut–brain interactions underlying inflammatory bowel disease-related depression have translational implications in regenerative medicine: a narrative review DOI
Hua Fu, Yang Liu

Regenerative medicine reports ., Journal Year: 2024, Volume and Issue: 1(1), P. 59 - 75

Published: Sept. 1, 2024

Inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis, are chronic gastrointestinal disorders characterized by relapsing intestinal inflammation. In addition to symptoms, patients with inflammatory diseases experience a disproportionately high prevalence of depression other neuropsychiatric comorbidities. The gut–brain axis, bidirectional communication system between the gut brain, has emerged as potential pathogenic link underlying this aberrant mind–gut interplay. This review synthesizes growing evidence implicating axis dysregulation central mechanism bridging inflammation development in diseases. Regenerative medicine offers promising new avenues for addressing these complex conditions. By focusing on regenerative therapies that target we explore approaches could repair or restore normal function both brain. These might alleviate proper signaling via neural, immune-mediated, endocrine, microbiome-related pathways, ultimately reversing neurochemical, structural, functional brain abnormalities implicated depressive neuropathology. Unraveling interactions disease-related through profound translational implications, paving way transformative diagnostic therapeutic paradigms address multisystemic burden debilitating conditions holistically.

Language: Английский

Citations

1
Centering prayer in the treatment of bipolar disorder DOI Creative Commons

Yanín Machado,

Mauricio Chinchilla,

Robert Hesse

et al.

World Journal of Advanced Research and Reviews, Journal Year: 2024, Volume and Issue: 21(3), P. 2314 - 2323

Published: March 30, 2024

Bipolar Disorder (BD), formerly manic-depressive illness or manic depression, is a lifelong mood disorder and mental health condition that causes intense shifts in mood, energy levels, thinking patterns, behavior. These can last for hours, days, weeks, months, interrupting the ability to carry out daily tasks. The manageable with medications, talk therapy, lifestyle changes, other treatments, but therapy results are unreliable many patients. Most faith traditions have two forms of prayer: discursive contemplative. believers practice prayer. Medical research has shown statistical healing effects prayer, there considerably less on contemplative Hesse reports method teaching CP by asking volunteer help demonstrate analogy between human Divine relationships following quoted phases., Therefore, we hypothesize might produce significant depression improvement BP Two neurologists double-blind diagnosed five patients complaining BD normal subjects. All cases expressed their belief God, so not non-theistic meditation. Patients will be free medication selected during depressive episodes. Among trait markers frontal alpha asymmetry,55,56, changes qEEG cordance. A very stable QEEG pattern, consisting asymmetry, was observed all Hence, this pattern used compare before after CP. Our main result showed focal left Alpha increment disappeared Conclusion: promising tool treating organizing function interplay among brain networks subserve Cognition-emotion interactions prefrontal cortex.

Language: Английский

Citations

0