Immuno-Haematologic Aspects of Dengue Infection: Biologic Insights and Clinical Implications DOI Open Access
Cherie S. Tan,

Clarice Shi Hui Choong,

Muhammad Bilal Abid

et al.

Published: May 14, 2024

Dengue infection is caused by the virus (DENV) and transmitted to humans infected female Aedes aegypti albopictus mosquitoes. There are nearly 100 million new dengue cases yearly in more than 120 countries with a five-fold increase incidence over past four decades. While many patients experience mild illness, subset suffer from severe disease which can be fatal. Dysregulated immune responses central pathogenesis of dengue, haematologic manifestations prominent feature disease. thrombocytopaenia coagulopathy major causes bleeding leucocyte abnormities emerging as important markers prognosis. In this review, we provide our perspective on clinical aspects pathophysiology dengue. We also discuss key gaps current practice areas addressed future research.

Language: Английский

Cross-species immune activation and immunobiotics: a new frontier in vector-borne pathogen control DOI
Alejandro Cabezas‐Cruz, Elianne Piloto‐Sardiñas, Pierre Tonnerre

et al.

Trends in Parasitology, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0
HUMAN MICROBIOTA IN DENGUE INFECTION: A NARRATIVE REVIEW DOI

Francesco Eugenio Romani,

Viravarn Luvira, Wiwat Chancharoenthana

et al.

Microbial Pathogenesis, Journal Year: 2025, Volume and Issue: 205, P. 107643 - 107643

Published: April 28, 2025

Language: Английский

Citations

0
Immuno-Haematologic Aspects of Dengue Infection: Biologic Insights and Clinical Implications DOI Creative Commons

Tan Jiao Jie Cherie,

Clarice Shi Hui Choong,

Muhammad Bilal Abid

et al.

Viruses, Journal Year: 2024, Volume and Issue: 16(7), P. 1090 - 1090

Published: July 6, 2024

Dengue infection is caused by the dengue virus (DENV) and transmitted to humans infected female

Language: Английский

Citations

3
Global Infectious Diseases between January and March 2024: Periodic Analysis DOI Creative Commons
Tingting Jiang, Xiaona Zhao,

Zhiyuan Tao

et al.

Zoonoses, Journal Year: 2024, Volume and Issue: 4(1)

Published: Jan. 1, 2024

In recent years, humanity has faced formidable challenges posed by infectious diseases. For example, previously controlled diseases have undergone resurgences, while ongoing pathogen mutations given rise to drug-resistant strains. These developments, coupled with changes in natural and societal factors, contributed the emergence of new Spring is a season prone diseases, common examples including influenza, measles, smallpox, dengue fever. are primarily transmitted through respiratory droplets, airborne transmission, close contact. To gain insight into global distribution we analyzed data from Global Epidemic Information Monitoring System, which was developed Shusi Technology, January March 2024.

Language: Английский

Citations

2
Role of Gut Microbiota in Dengue DOI
Adriana Pedreáñez,

Yenddy Carrero,

Renata Vargas

et al.

Reviews in Medical Virology, Journal Year: 2024, Volume and Issue: 34(5)

Published: Aug. 30, 2024

ABSTRACT Dengue is a disease caused by flavivirus (DENV) and transmitted the bite of mosquito, primarily Aedes aegypti albopictus species. Previous studies have demonstrated relationship between host gut microbiota evolution dengue. It seems to be bidirectional relationship, in which DENV can affect inducing alterations related intestinal permeability, leading release molecules from dysbiosis that influence The role angiotensin II (Ang II) microbiota/dengue not well understood, but it known renin‐angiotensin system (RAS) present tract interacts with microbiota. possible effect Ang on microbiota/Ang II/dengue summarised as follows: presence induced hypertension, increase angiotensinogen, chymase, microRNAs during disease, induction vascular dysfunction, production trimethylamine N‐oxide brain/microbiota all are elements dengue could part interactions. These findings suggest potential use synthesis blockers AT1 receptor antagonists therapeutic drugs

Language: Английский

Citations

2
Immuno-Haematologic Aspects of Dengue Infection: Biologic Insights and Clinical Implications DOI Open Access
Cherie S. Tan,

Clarice Shi Hui Choong,

Muhammad Bilal Abid

et al.

Published: May 14, 2024

Dengue infection is caused by the virus (DENV) and transmitted to humans infected female Aedes aegypti albopictus mosquitoes. There are nearly 100 million new dengue cases yearly in more than 120 countries with a five-fold increase incidence over past four decades. While many patients experience mild illness, subset suffer from severe disease which can be fatal. Dysregulated immune responses central pathogenesis of dengue, haematologic manifestations prominent feature disease. thrombocytopaenia coagulopathy major causes bleeding leucocyte abnormities emerging as important markers prognosis. In this review, we provide our perspective on clinical aspects pathophysiology dengue. We also discuss key gaps current practice areas addressed future research.

Language: Английский

Citations

0