Research progress of nano drug delivery systems in the anti-tumor treatment of traditional Chinese medicine monomers DOI Creative Commons
Bocui Song, Shuang Li, Shuang Zhang

et al.

PeerJ, Journal Year: 2025, Volume and Issue: 13, P. e19332 - e19332

Published: April 24, 2025

Tumors pose a serious threat to global public health and are usually treated from two aspects: tumor cells microenvironment. Compared with traditional chemotherapy drugs, Chinese medicine (TCM) monomers have advantages in treatment, such as multiple targets, levels synergistic intervention. However, most TCM active ingredients disadvantages poor water solubility stability, which restrict their clinical application. Nano drug delivery systems the functions of improving bioavailability anti-tumor ingredients, enhancing tissue targeting, achieving controlled release, inhibiting multidrug resistance. free monomers, they higher therapeutic effects fewer side effects. This article summarizes five commonly used monomer nanocarriers, including lipid nanomaterials, exosomes, polymer micelles, carbon nanotubes, dendrimers, explains mechanisms after combining TCM, cell proliferation metastasis, regulating microenvironment, etc . At same time, potential nano combined radiotherapy immunotherapy is discussed, well current problems toxicity, long-term complex amplification process, future development directions, aiming provide reference for promoting application ingredients.

Language: Английский

The Special Issue “The 20th Anniversary of Pharmaceuticals—Multi-Targeted Natural Products as Therapeutics” Editorial—Multi-Targeted Therapeutics from Natural Sources: What Do We Know? DOI Creative Commons
Elena Y. Enioutina, Kathleen M. Job, Catherine M.T. Sherwin

et al.

Pharmaceuticals, Journal Year: 2025, Volume and Issue: 18(4), P. 442 - 442

Published: March 21, 2025

Herbal and marine products in the form of extracts, infusions, decoctions have been used for centuries folk traditional medicine [...]

Language: Английский

Citations

0
Research progress of nano drug delivery systems in the anti-tumor treatment of traditional Chinese medicine monomers DOI Creative Commons
Bocui Song, Shuang Li, Shuang Zhang

et al.

PeerJ, Journal Year: 2025, Volume and Issue: 13, P. e19332 - e19332

Published: April 24, 2025

Tumors pose a serious threat to global public health and are usually treated from two aspects: tumor cells microenvironment. Compared with traditional chemotherapy drugs, Chinese medicine (TCM) monomers have advantages in treatment, such as multiple targets, levels synergistic intervention. However, most TCM active ingredients disadvantages poor water solubility stability, which restrict their clinical application. Nano drug delivery systems the functions of improving bioavailability anti-tumor ingredients, enhancing tissue targeting, achieving controlled release, inhibiting multidrug resistance. free monomers, they higher therapeutic effects fewer side effects. This article summarizes five commonly used monomer nanocarriers, including lipid nanomaterials, exosomes, polymer micelles, carbon nanotubes, dendrimers, explains mechanisms after combining TCM, cell proliferation metastasis, regulating microenvironment, etc . At same time, potential nano combined radiotherapy immunotherapy is discussed, well current problems toxicity, long-term complex amplification process, future development directions, aiming provide reference for promoting application ingredients.

Language: Английский

Citations

0