Ocular immune‐related diseases: molecular mechanisms and therapy

MedComm, Journal Year: 2024, Volume and Issue: 5(12)

Published: Nov. 28, 2024

Abstract Ocular immune‐related diseases, represent a spectrum of conditions driven by immune system dysregulation, include but not limit to uveitis, diabetic retinopathy, age‐related macular degeneration, Graves’ ophthalmopathy, etc. The molecular and cellular mechanisms underlying these diseases are typically dysfunctioned responses targeting ocular tissues, resulting in inflammation tissue damage. Recent advances have further elucidated the pivotal role different development, progression, as well management various diseases. However, there is currently relative lack connection between treatments several In this review, we discuss recent findings related immunopathogenesis above‐mentioned particular, summarize types cells, inflammatory mediators, associated signaling pathways that involved pathophysiology ophthalmopathies. Furthermore, also future directions utilizing anti‐inflammatory regime This will facilitate better understanding pathogenesis provide new insights for treatment approaches.

Language: Английский

Multifunctional peptide-drug conjugate CORM-401@R9: A novel approach to combat oxidative stress in cataracts

Free Radical Biology and Medicine, Journal Year: 2024, Volume and Issue: 227, P. 570 - 581

Published: Dec. 10, 2024

Language: Английский